IL40080A - 4-aza-benzimidazoles,their production and pharmaceutical compositions containing them - Google Patents
4-aza-benzimidazoles,their production and pharmaceutical compositions containing themInfo
- Publication number
- IL40080A IL40080A IL40080A IL4008072A IL40080A IL 40080 A IL40080 A IL 40080A IL 40080 A IL40080 A IL 40080A IL 4008072 A IL4008072 A IL 4008072A IL 40080 A IL40080 A IL 40080A
- Authority
- IL
- Israel
- Prior art keywords
- benzimidazoles
- aza
- production
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT748871A AT315831B (de) | 1971-08-26 | 1971-08-26 | Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen |
Publications (2)
Publication Number | Publication Date |
---|---|
IL40080A0 IL40080A0 (en) | 1972-10-29 |
IL40080A true IL40080A (en) | 1975-12-31 |
Family
ID=3596529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL40080A IL40080A (en) | 1971-08-26 | 1972-08-09 | 4-aza-benzimidazoles,their production and pharmaceutical compositions containing them |
Country Status (19)
Country | Link |
---|---|
JP (1) | JPS4832898A (fr) |
AR (1) | AR199879A1 (fr) |
AT (1) | AT315831B (fr) |
AU (1) | AU461671B2 (fr) |
BE (1) | BE788065A (fr) |
BR (1) | BR7205845A (fr) |
CA (1) | CA979907A (fr) |
CH (1) | CH592660A5 (fr) |
DD (1) | DD99580A5 (fr) |
DE (1) | DE2241575A1 (fr) |
ES (1) | ES405982A1 (fr) |
FR (1) | FR2150820B1 (fr) |
GB (1) | GB1397645A (fr) |
HU (1) | HU166382B (fr) |
IL (1) | IL40080A (fr) |
NL (1) | NL7211407A (fr) |
SU (1) | SU557758A3 (fr) |
YU (1) | YU34897B (fr) |
ZA (1) | ZA725868B (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7956056B2 (en) | 2006-08-02 | 2011-06-07 | Cytokinetics, Inc. | Certain 1H-imidazo[4,5-B]pyrazin-2(3H)-ones and 1H-imidazo[4,5-B]pyrazin-2-ols, compositions thereof, and methods for their use |
US8227603B2 (en) | 2006-08-01 | 2012-07-24 | Cytokinetics, Inc. | Modulating skeletal muscle |
US8299248B2 (en) | 2006-08-02 | 2012-10-30 | Cytokinetics, Incorporated | Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use |
US10272082B2 (en) | 2011-07-13 | 2019-04-30 | Cytokinetics, Inc. | Combination ALS therapy |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1140119A (fr) * | 1978-04-03 | 1983-01-25 | Joseph Torremans | Nouvelles n-heterocycle-4-piperidinamines |
US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
US4772600A (en) * | 1986-06-09 | 1988-09-20 | A. H. Robins Company, Inc. | Fused imidazoheterocyclic compounds and pharmaceutical compositions |
JP2679745B2 (ja) * | 1989-06-29 | 1997-11-19 | 明治製菓株式会社 | アゾール誘導体及びそれらを有効成分とする抗潰瘍剤 |
US5200407A (en) * | 1989-06-29 | 1993-04-06 | Meiji Seika Kaburhiki Kaisha | Azole derivatives and anti-ulcerative composition containing same |
US6093728A (en) | 1997-09-26 | 2000-07-25 | Asta Medica Aktiengesellschaft | Methods of modulating serine/threonine protein kinase function with azabenzimidazole-based compounds |
US7851484B2 (en) * | 2007-03-30 | 2010-12-14 | Cytokinetics, Inc. | Certain chemical entities, compositions, and methods |
BR112013028895A2 (pt) | 2011-05-10 | 2016-08-09 | Bayer Ip Gmbh | (tio)carbonilamidinas bicíclicas |
EP2733141B1 (fr) * | 2011-07-15 | 2019-01-09 | Shionogi & Co., Ltd. | Dérivé d'azabenzimidazole possédant une activité activant l'ampk |
-
0
- BE BE788065D patent/BE788065A/fr unknown
-
1971
- 1971-08-26 AT AT748871A patent/AT315831B/de not_active IP Right Cessation
-
1972
- 1972-07-26 DD DD164684A patent/DD99580A5/xx unknown
- 1972-08-09 IL IL40080A patent/IL40080A/xx unknown
- 1972-08-09 YU YU2041/72A patent/YU34897B/xx unknown
- 1972-08-14 CH CH1201872A patent/CH592660A5/xx not_active IP Right Cessation
- 1972-08-18 SU SU1821216A patent/SU557758A3/ru active
- 1972-08-19 ES ES405982A patent/ES405982A1/es not_active Expired
- 1972-08-21 NL NL7211407A patent/NL7211407A/xx not_active Application Discontinuation
- 1972-08-22 FR FR7229915A patent/FR2150820B1/fr not_active Expired
- 1972-08-24 GB GB3940272A patent/GB1397645A/en not_active Expired
- 1972-08-24 DE DE2241575A patent/DE2241575A1/de active Pending
- 1972-08-25 BR BR5845/72A patent/BR7205845A/pt unknown
- 1972-08-25 HU HUDE789A patent/HU166382B/hu unknown
- 1972-08-25 JP JP47085203A patent/JPS4832898A/ja active Pending
- 1972-08-25 AU AU45981/72A patent/AU461671B2/en not_active Expired
- 1972-08-25 ZA ZA725868A patent/ZA725868B/xx unknown
- 1972-08-25 CA CA150,204A patent/CA979907A/en not_active Expired
- 1972-08-28 AR AR243765A patent/AR199879A1/es active
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8227603B2 (en) | 2006-08-01 | 2012-07-24 | Cytokinetics, Inc. | Modulating skeletal muscle |
US7956056B2 (en) | 2006-08-02 | 2011-06-07 | Cytokinetics, Inc. | Certain 1H-imidazo[4,5-B]pyrazin-2(3H)-ones and 1H-imidazo[4,5-B]pyrazin-2-ols, compositions thereof, and methods for their use |
US8293761B2 (en) | 2006-08-02 | 2012-10-23 | Cytokinetics, Inc. | Certain chemical entities, compositions and methods |
US8299248B2 (en) | 2006-08-02 | 2012-10-30 | Cytokinetics, Incorporated | Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use |
US8716291B2 (en) | 2006-08-02 | 2014-05-06 | Cytokinetics, Inc. | Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use |
US10766899B2 (en) | 2006-08-02 | 2020-09-08 | Cytokinetics, Incorporated | Methods for preparing substituted imidazo[4,5-b]pyrazines |
US10272082B2 (en) | 2011-07-13 | 2019-04-30 | Cytokinetics, Inc. | Combination ALS therapy |
Also Published As
Publication number | Publication date |
---|---|
FR2150820B1 (fr) | 1975-10-17 |
HU166382B (fr) | 1975-03-28 |
NL7211407A (fr) | 1973-02-28 |
ES405982A1 (es) | 1975-09-16 |
DD99580A5 (fr) | 1973-08-12 |
SU557758A3 (ru) | 1977-05-05 |
BR7205845A (pt) | 1976-05-04 |
AU461671B2 (en) | 1975-06-05 |
ZA725868B (en) | 1973-05-30 |
FR2150820A1 (fr) | 1973-04-13 |
GB1397645A (en) | 1975-06-11 |
CH592660A5 (fr) | 1977-10-31 |
BE788065A (fr) | 1973-02-26 |
AU4598172A (en) | 1974-02-28 |
YU204172A (en) | 1979-10-31 |
YU34897B (en) | 1980-04-30 |
BR7205845D0 (pt) | 1973-07-03 |
IL40080A0 (en) | 1972-10-29 |
DE2241575A1 (de) | 1973-03-08 |
AR199879A1 (es) | 1974-10-08 |
CA979907A (en) | 1975-12-16 |
AT315831B (de) | 1974-06-10 |
JPS4832898A (fr) | 1973-05-02 |
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