IL34050A - New cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin - Google Patents

New cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin

Info

Publication number
IL34050A
IL34050A IL34050A IL3405070A IL34050A IL 34050 A IL34050 A IL 34050A IL 34050 A IL34050 A IL 34050A IL 3405070 A IL3405070 A IL 3405070A IL 34050 A IL34050 A IL 34050A
Authority
IL
Israel
Prior art keywords
ester
group
cephalexin
hydrogen
process according
Prior art date
Application number
IL34050A
Other languages
English (en)
Other versions
IL34050A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL34050A0 publication Critical patent/IL34050A0/xx
Publication of IL34050A publication Critical patent/IL34050A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
IL34050A 1969-03-18 1970-03-10 New cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin IL34050A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80831369A 1969-03-18 1969-03-18

Publications (2)

Publication Number Publication Date
IL34050A0 IL34050A0 (en) 1970-05-21
IL34050A true IL34050A (en) 1973-02-28

Family

ID=25198435

Family Applications (1)

Application Number Title Priority Date Filing Date
IL34050A IL34050A (en) 1969-03-18 1970-03-10 New cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin

Country Status (16)

Country Link
US (1) US3632850A (xx)
JP (1) JPS5017991B1 (xx)
AT (1) AT305492B (xx)
BE (1) BE747382A (xx)
BR (1) BR6915024D0 (xx)
CA (1) CA985674A (xx)
CH (1) CH554896A (xx)
CY (1) CY708A (xx)
DK (1) DK143342C (xx)
ES (1) ES377688A1 (xx)
FR (1) FR2039032A5 (xx)
GB (1) GB1270633A (xx)
IE (1) IE34181B1 (xx)
IL (1) IL34050A (xx)
MY (1) MY7300494A (xx)
NL (1) NL7003887A (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU35448B (en) * 1970-02-18 1981-02-28 Koninkl Gist Spiritus Process for obtaining 7-substituted amino-deacetoxy cephalosporanic acids
US3862181A (en) * 1970-10-28 1975-01-21 Squibb & Sons Inc Process for preparing cephalosporins
US4003894A (en) * 1971-08-17 1977-01-18 Gist-Brocades N.V. Preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
JPS536158B2 (xx) * 1972-03-23 1978-03-04
JPS551272B2 (xx) * 1972-04-14 1980-01-12
JPS4970989A (xx) * 1972-11-15 1974-07-09
JPS50150989U (xx) * 1974-05-31 1975-12-16
US4091214A (en) * 1977-02-25 1978-05-23 Eli Lilly And Company De-esterification process for cephalosporins
US4379739A (en) * 1980-03-31 1983-04-12 Eli Lilly And Company Electrolytic reduction of cephalosporin p-nitrobenzyl esters
CA1164402A (en) * 1980-03-31 1984-03-27 David A. Hall Electrolytic reduction of cephalosporin p-nitrobenzyl esters

Also Published As

Publication number Publication date
DK143342B (da) 1981-08-10
CY708A (en) 1973-10-01
BR6915024D0 (pt) 1973-05-24
BE747382A (fr) 1970-09-14
DE2012955A1 (de) 1970-09-24
IL34050A0 (en) 1970-05-21
ES377688A1 (es) 1972-08-01
IE34181B1 (en) 1975-03-05
MY7300494A (en) 1973-12-31
IE34181L (en) 1970-09-18
US3632850A (en) 1972-01-04
CA985674A (en) 1976-03-16
CH554896A (de) 1974-10-15
NL7003887A (xx) 1970-09-22
GB1270633A (en) 1972-04-12
DE2012955B2 (de) 1976-05-13
DK143342C (da) 1981-12-07
FR2039032A5 (xx) 1971-01-08
JPS5017991B1 (xx) 1975-06-25
AT305492B (de) 1973-02-26

Similar Documents

Publication Publication Date Title
IL34050A (en) New cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin
ES427859A1 (es) Un procedimiento para la preparacion de compuestos de cefa-losporina.
JPWO2011093294A1 (ja) セファロスポリン誘導体の製造方法
IE42144L (en) Cephalosporin compounds.
US4297352A (en) Novel oximes
ES412859A1 (es) Un procedimiento para la preparacion de un derivado de 7- (alfa hidroxi-alfa-fenil) acetamido - 3 - (1 - metil - 1h - tetrazol - 5 - iltiometil) cefalosporina.
IE36353B1 (en) Rearrangement of 6-acylamidopenicillanic acid sulfoxides and production fo cephalexin or hetacephalexin
IE33580L (en) 2-acyloxy cephalosporins
GB1227014A (xx)
IE38869B1 (en) Alpha-aminoacyl cephalosporin ethers
GB1460914A (en) 3-thiolated-7-acylamido-cephalosporanic acid derivatives processes for preparing them and pharmaceutical compositions 0mprising them
ES431673A1 (es) Un procedimiento para la preparacion de compuestos de 7- acilamido-7-metoxi-cefalosporina.
GB1314628A (en) Method for preparing penicillin sulphoxides
JPS61263984A (ja) β−ラクタム誘導体の製造方法
ES467637A1 (es) Un nuevo procedimiento para preparar un compuesto de cefa- losporina
KR830000686B1 (ko) 세팔로스포린 화합물의 제조방법
AU2003236834A1 (en) Hydroxamic acid derivatives
ATE32724T1 (de) Cephalosporinverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
IE39344B1 (en) Method of preparing substituted cephalosporins and penicillins
GB1570095A (en) 7-aminocephalosporin intermediates
US3839328A (en) Use of mixed anhydride protecting group in cleaving acyl groups from cephalosporins and penicillins
US5637694A (en) Preparation and use of 7-[(2-carboalkoxy-1-methylethenyl)amino]-3-hydroxymethyl-3-cephem-4-carboxylic acids
FI58132C (fi) Foerfarande foer framstaellning av 3-metyl- 3-cefem-4-karboxylsyrafoereningar
IE46175L (en) Preparation of 3-heterocyclylthiomethyl cephalosporins from¹3-methylene cephalosporins.
PT1196420E (pt) Processo de sintese de derivados de beta-lactamo