IL33326A - Process for purifying and improving the yield of cephaloglycin antibiotic - Google Patents

Process for purifying and improving the yield of cephaloglycin antibiotic

Info

Publication number
IL33326A
IL33326A IL33326A IL3332669A IL33326A IL 33326 A IL33326 A IL 33326A IL 33326 A IL33326 A IL 33326A IL 3332669 A IL3332669 A IL 3332669A IL 33326 A IL33326 A IL 33326A
Authority
IL
Israel
Prior art keywords
cephaloglycin
antibiotic
purifying
yield
improving
Prior art date
Application number
IL33326A
Other languages
English (en)
Other versions
IL33326A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL33326A0 publication Critical patent/IL33326A0/xx
Publication of IL33326A publication Critical patent/IL33326A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
IL33326A 1969-02-17 1969-11-07 Process for purifying and improving the yield of cephaloglycin antibiotic IL33326A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79999169A 1969-02-17 1969-02-17

Publications (2)

Publication Number Publication Date
IL33326A0 IL33326A0 (en) 1970-01-29
IL33326A true IL33326A (en) 1973-02-28

Family

ID=25177238

Family Applications (1)

Application Number Title Priority Date Filing Date
IL33326A IL33326A (en) 1969-02-17 1969-11-07 Process for purifying and improving the yield of cephaloglycin antibiotic

Country Status (17)

Country Link
US (1) US3496171A (es)
AT (1) AT293618B (es)
BE (1) BE742086A (es)
BR (1) BR6914264D0 (es)
CH (1) CH531006A (es)
CS (1) CS157076B2 (es)
CY (1) CY784A (es)
DE (1) DE1958329C3 (es)
ES (1) ES373868A1 (es)
FR (1) FR2031460B1 (es)
GB (1) GB1254148A (es)
IE (1) IE33619B1 (es)
IL (1) IL33326A (es)
MY (1) MY7500052A (es)
NL (1) NL6917696A (es)
PL (1) PL83176B1 (es)
SE (1) SE372536B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692781A (en) * 1971-02-26 1972-09-19 Glaxo Lab Ltd Recovery of pure cephalexin from acidic reaction mixtures
US4054738A (en) * 1975-12-22 1977-10-18 Eli Lilly And Company Sodium cefamandole crystalline forms
WO2011139254A2 (en) * 2010-05-04 2011-11-10 Mahmut Bilgic Pharmaceutical formulations compising cefuroxime axetil

Also Published As

Publication number Publication date
CH531006A (fr) 1972-11-30
FR2031460B1 (es) 1973-04-06
IE33619B1 (en) 1974-09-04
FR2031460A1 (es) 1970-11-20
DE1958329C3 (de) 1974-05-02
GB1254148A (en) 1971-11-17
US3496171A (en) 1970-02-17
AT293618B (de) 1971-10-25
CS157076B2 (es) 1974-08-23
PL83176B1 (es) 1975-12-31
IE33619L (en) 1970-08-17
NL6917696A (es) 1970-08-19
CY784A (en) 1976-06-01
BR6914264D0 (pt) 1973-02-22
DE1958329A1 (de) 1970-10-22
MY7500052A (en) 1975-12-31
IL33326A0 (en) 1970-01-29
SE372536B (es) 1974-12-23
BE742086A (es) 1970-05-25
ES373868A1 (es) 1972-02-16
DE1958329B2 (de) 1973-09-27

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