IL326531A - אנלוגים של Cap ושיטות שימוש בהם - Google Patents
אנלוגים של Cap ושיטות שימוש בהםInfo
- Publication number
- IL326531A IL326531A IL326531A IL32653126A IL326531A IL 326531 A IL326531 A IL 326531A IL 326531 A IL326531 A IL 326531A IL 32653126 A IL32653126 A IL 32653126A IL 326531 A IL326531 A IL 326531A
- Authority
- IL
- Israel
- Prior art keywords
- methods
- cap analogs
- analogs
- cap
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363536844P | 2023-09-06 | 2023-09-06 | |
| PCT/US2024/045502 WO2025054401A2 (en) | 2023-09-06 | 2024-09-06 | Cap analogs and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL326531A true IL326531A (he) | 2026-04-01 |
Family
ID=92895771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL326531A IL326531A (he) | 2023-09-06 | 2024-09-06 | אנלוגים של Cap ושיטות שימוש בהם |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN121794279A (he) |
| AU (1) | AU2024337685A1 (he) |
| IL (1) | IL326531A (he) |
| TW (1) | TW202526022A (he) |
| WO (1) | WO2025054401A2 (he) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026010855A1 (en) | 2024-07-02 | 2026-01-08 | Trilink Biotechnologies, Llc | Modified rna for increasing protein expression |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2998800A (en) | 1999-03-24 | 2000-10-09 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | N-acylphosphoramidites and their use in oligonucleotide synthesis |
| AU2007268075C1 (en) | 2006-06-01 | 2013-03-07 | Trilink Biotechnologies | Chemically modified oligonucleotide primers for nucleic acid amplification |
| ES2964690T3 (es) * | 2015-09-21 | 2024-04-09 | Trilink Biotechnologies Llc | Método para sintetizar ARN con caperuza 5' |
| PL248416B1 (pl) * | 2020-02-12 | 2025-12-08 | Explorna Therapeutics Spolka Z Ograniczona Odpowiedzialnoscia | Nowe analogi kapu końca 5’ mRNA, cząsteczka RNA je zawierająca, ich zastosowania i sposób syntezy cząsteczki RNA i peptydu |
| EP3901261A1 (en) * | 2020-04-22 | 2021-10-27 | BioNTech RNA Pharmaceuticals GmbH | Coronavirus vaccine |
| CN116368226A (zh) * | 2020-09-04 | 2023-06-30 | 维乎医疗有限公司 | 用于加帽rna的组合物和方法 |
| KR20220140140A (ko) * | 2021-04-09 | 2022-10-18 | 한미정밀화학주식회사 | 캡핑된 올리고뉴클레오티드 프라이머 및 이의 용도 |
| CN117858885A (zh) * | 2021-07-05 | 2024-04-09 | 国立研究开发法人科学技术振兴机构 | 核苷酸类的纯化方法和核苷酸类的纯化装置以及疏水性试剂和疏水性底物 |
| US20250122546A1 (en) * | 2021-10-28 | 2025-04-17 | BioNTech SE | Rna constructs and uses thereof |
| JP2025507894A (ja) * | 2022-03-01 | 2025-03-21 | ヴァーヴ・セラピューティクス，インコーポレーテッド | Ｒｎａをキャッピングするための組成物及び方法 |
-
2024
- 2024-09-06 IL IL326531A patent/IL326531A/he unknown
- 2024-09-06 CN CN202480056968.8A patent/CN121794279A/zh active Pending
- 2024-09-06 AU AU2024337685A patent/AU2024337685A1/en active Pending
- 2024-09-06 WO PCT/US2024/045502 patent/WO2025054401A2/en active Pending
- 2024-09-06 TW TW113133883A patent/TW202526022A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025054401A3 (en) | 2025-05-08 |
| AU2024337685A1 (en) | 2026-02-26 |
| CN121794279A (zh) | 2026-04-03 |
| WO2025054401A2 (en) | 2025-03-13 |
| TW202526022A (zh) | 2025-07-01 |
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