IL325352A - אנאלוגי אינקרטין ושימושם - Google Patents
אנאלוגי אינקרטין ושימושםInfo
- Publication number
- IL325352A IL325352A IL325352A IL32535225A IL325352A IL 325352 A IL325352 A IL 325352A IL 325352 A IL325352 A IL 325352A IL 32535225 A IL32535225 A IL 32535225A IL 325352 A IL325352 A IL 325352A
- Authority
- IL
- Israel
- Prior art keywords
- incretin analogs
- incretin
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Details Of Garments (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762608644P | 2017-12-21 | 2017-12-21 | |
| PCT/US2018/065605 WO2019125929A1 (en) | 2017-12-21 | 2018-12-14 | Incretin analogs and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL325352A true IL325352A (he) | 2026-02-01 |
Family
ID=65003515
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL275469A IL275469B1 (he) | 2017-12-21 | 2020-06-17 | אנאלוגי אינקרטין ושימושם |
| IL325352A IL325352A (he) | 2017-12-21 | 2025-12-15 | אנאלוגי אינקרטין ושימושם |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL275469A IL275469B1 (he) | 2017-12-21 | 2020-06-17 | אנאלוגי אינקרטין ושימושם |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US11834486B2 (he) |
| EP (1) | EP3727425A1 (he) |
| JP (2) | JP6987993B2 (he) |
| KR (1) | KR102440323B1 (he) |
| CN (1) | CN111511387A (he) |
| AR (1) | AR113487A1 (he) |
| AU (1) | AU2018388895B2 (he) |
| BR (1) | BR112020010410A2 (he) |
| CA (1) | CA3084004C (he) |
| CL (1) | CL2020001636A1 (he) |
| CO (1) | CO2020006253A2 (he) |
| CR (1) | CR20200256A (he) |
| DO (1) | DOP2020000124A (he) |
| EA (1) | EA202091284A1 (he) |
| EC (1) | ECSP20032306A (he) |
| IL (2) | IL275469B1 (he) |
| JO (1) | JOP20200136A1 (he) |
| MA (1) | MA51287A (he) |
| MX (2) | MX2020006547A (he) |
| MY (1) | MY199545A (he) |
| PE (1) | PE20200926A1 (he) |
| PH (1) | PH12020551024A1 (he) |
| SG (1) | SG11202004359YA (he) |
| TW (2) | TWI767095B (he) |
| UA (1) | UA127589C2 (he) |
| WO (1) | WO2019125929A1 (he) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR113486A1 (es) * | 2017-12-21 | 2020-05-06 | Lilly Co Eli | Análogos de incretina y sus usos |
| TWI767095B (zh) * | 2017-12-21 | 2022-06-11 | 美商美國禮來大藥廠 | 腸促胰島素(incretin)類似物及其用途 |
| KR20210031533A (ko) | 2018-07-23 | 2021-03-19 | 일라이 릴리 앤드 캄파니 | Gip/glp1 공효능제 화합물 |
| AR119471A1 (es) * | 2019-08-01 | 2021-12-22 | Lilly Co Eli | Compuestos agonistas de gipr |
| MY201700A (en) | 2019-08-19 | 2024-03-13 | Lilly Co Eli | Methods of making incretin analogs |
| TWI795698B (zh) * | 2019-12-18 | 2023-03-11 | 美商美國禮來大藥廠 | 腸促胰島素(incretin)類似物及其用途 |
| US20230265151A1 (en) * | 2020-01-23 | 2023-08-24 | Eli Lilly And Company | Gip/glp1 co-agonist compounds |
| EP4183419A4 (en) * | 2020-07-17 | 2025-04-02 | Hanmi Pharm. Co., Ltd. | THERAPEUTIC USE OF A COMBINATION WITH A LONG-ACTING TRIPLE AGONIST CONJUGATE OR TRIPLE AGONIST |
| CA3187742A1 (en) * | 2020-08-14 | 2022-02-17 | Seungjae Baek | Pharmaceutical composition comprising long-acting conjugate of triple glucagon/glp-1/gip receptor agonist |
| JP2023550594A (ja) | 2020-10-30 | 2023-12-04 | ノヴォ ノルディスク アー／エス | Ｇｌｐ－１、ｇｉｐ、およびグルカゴン受容体三重作動薬 |
| TW202423476A (zh) | 2021-03-23 | 2024-06-16 | 美商美國禮來大藥廠 | 含腸促胰島素(incretin)類似物之組合物及其用途 |
| CN117062618B (zh) * | 2021-05-26 | 2026-01-02 | 联邦生物科技(珠海横琴)有限公司 | 多激动剂及其应用 |
| CN115572326B (zh) * | 2021-06-21 | 2025-01-10 | 广东东阳光药业股份有限公司 | Glp-1、gcg和gip受体的三重激动剂 |
| JP2024524180A (ja) | 2021-06-23 | 2024-07-05 | イーライ リリー アンド カンパニー | インクレチン類似体の使用方法及びインクレチン類似体を含む組成物 |
| WO2023088140A1 (zh) * | 2021-11-19 | 2023-05-25 | 南京明德新药研发有限公司 | 订合肽及其应用 |
| CN116162147B (zh) * | 2021-11-24 | 2023-10-03 | 成都奥达生物科技有限公司 | 一种长效胰岛素类似物 |
| KR20250075689A (ko) * | 2022-09-28 | 2025-05-28 | 선샤인 레이크 파르마 컴퍼니 리미티드 | Glp-1/gcg/gip 삼중-수용체 작용제 및 이의 용도 |
| KR20250141711A (ko) | 2022-12-30 | 2025-09-29 | 알지파마 에이에스 | 경구 투여되는 폴리펩타이드 치료제의 전신 생체이용률을 증가시키는 조성물 및 방법 |
| US20240270821A1 (en) | 2023-01-31 | 2024-08-15 | Eli Lilly And Company | Gip/glp1/gcg tri-receptor agonists and uses thereof |
| CN121002051A (zh) * | 2023-04-11 | 2025-11-21 | 上海多米瑞生物技术有限公司 | 肠促胰素类似物及其制备方法和应用 |
| CN120349393A (zh) * | 2023-11-06 | 2025-07-22 | 成都奥达生物科技有限公司 | 一种三激动剂化合物 |
| CN120329412A (zh) * | 2023-11-06 | 2025-07-18 | 成都奥达生物科技有限公司 | 一种三激动剂化合物 |
| CN119241684B (zh) * | 2024-11-22 | 2025-02-25 | 徐州医科大学 | 一种肠促胰岛素类似物及其用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA021146B1 (ru) | 2009-03-27 | 2015-04-30 | Глаксо Груп Лимитед | Продукты слияния и конъюгаты лекарственных средств |
| AR092873A1 (es) | 2012-09-26 | 2015-05-06 | Cadila Healthcare Ltd | Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon |
| US10093713B2 (en) * | 2013-11-06 | 2018-10-09 | Zealand Pharma A/S | GIP-GLP-1 dual agonist compounds and methods |
| MX369770B (es) * | 2013-11-06 | 2019-11-21 | Zealand Pharma As | Compuestos agonistas triples de glucagón-glp-1-gip. |
| JOP20200119A1 (ar) | 2015-01-09 | 2017-06-16 | Lilly Co Eli | مركبات مساعد مشترك من gip وglp-1 |
| WO2016198624A1 (en) | 2015-06-12 | 2016-12-15 | Sanofi | Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists |
| AR104932A1 (es) * | 2015-06-22 | 2017-08-23 | Lilly Co Eli | Compuestos co-agonistas del glucagón y péptido-1 similar al glugacón (glp-1) |
| HUE059737T2 (hu) | 2015-12-31 | 2022-12-28 | Hanmi Pharm Ind Co Ltd | Glükagon, GLP-1 és GIP receptor aktiváló tripla aktivátor |
| EP3217027A1 (de) | 2016-03-08 | 2017-09-13 | HILTI Aktiengesellschaft | Breites einlageelement zum einfassen einer ankerstange |
| TWI767095B (zh) * | 2017-12-21 | 2022-06-11 | 美商美國禮來大藥廠 | 腸促胰島素(incretin)類似物及其用途 |
-
2018
- 2018-12-05 TW TW107143623A patent/TWI767095B/zh active
- 2018-12-05 TW TW111118551A patent/TWI810937B/zh active
- 2018-12-06 AR ARP180103573A patent/AR113487A1/es unknown
- 2018-12-14 EP EP18830614.6A patent/EP3727425A1/en active Pending
- 2018-12-14 JP JP2020532952A patent/JP6987993B2/ja active Active
- 2018-12-14 CR CR20200256A patent/CR20200256A/es unknown
- 2018-12-14 EA EA202091284A patent/EA202091284A1/ru unknown
- 2018-12-14 KR KR1020207017385A patent/KR102440323B1/ko active Active
- 2018-12-14 PE PE2020000800A patent/PE20200926A1/es unknown
- 2018-12-14 WO PCT/US2018/065605 patent/WO2019125929A1/en not_active Ceased
- 2018-12-14 BR BR112020010410-8A patent/BR112020010410A2/pt unknown
- 2018-12-14 US US16/769,015 patent/US11834486B2/en active Active
- 2018-12-14 JO JOP/2020/0136A patent/JOP20200136A1/ar unknown
- 2018-12-14 CA CA3084004A patent/CA3084004C/en active Active
- 2018-12-14 MA MA051287A patent/MA51287A/fr unknown
- 2018-12-14 CN CN201880082714.8A patent/CN111511387A/zh active Pending
- 2018-12-14 MY MYPI2020003206A patent/MY199545A/en unknown
- 2018-12-14 UA UAA202002893A patent/UA127589C2/uk unknown
- 2018-12-14 MX MX2020006547A patent/MX2020006547A/es unknown
- 2018-12-14 AU AU2018388895A patent/AU2018388895B2/en active Active
- 2018-12-14 SG SG11202004359YA patent/SG11202004359YA/en unknown
-
2020
- 2020-05-22 CO CONC2020/0006253A patent/CO2020006253A2/es unknown
- 2020-06-17 CL CL2020001636A patent/CL2020001636A1/es unknown
- 2020-06-17 PH PH12020551024A patent/PH12020551024A1/en unknown
- 2020-06-17 IL IL275469A patent/IL275469B1/he unknown
- 2020-06-17 DO DO2020000124A patent/DOP2020000124A/es unknown
- 2020-06-19 EC ECSENADI202032306A patent/ECSP20032306A/es unknown
- 2020-07-13 MX MX2025003745A patent/MX2025003745A/es unknown
-
2021
- 2021-12-01 JP JP2021195036A patent/JP2022043082A/ja not_active Withdrawn
-
2023
- 2023-10-30 US US18/497,390 patent/US20240190936A1/en active Pending
-
2025
- 2025-12-15 IL IL325352A patent/IL325352A/he unknown
Also Published As
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