IL325309A - Synthesis of 2-(carbamoyoxy)-n,n,n-trimethylethan-1-aminium salts - Google Patents

Synthesis of 2-(carbamoyoxy)-n,n,n-trimethylethan-1-aminium salts

Info

Publication number
IL325309A
IL325309A IL325309A IL32530925A IL325309A IL 325309 A IL325309 A IL 325309A IL 325309 A IL325309 A IL 325309A IL 32530925 A IL32530925 A IL 32530925A IL 325309 A IL325309 A IL 325309A
Authority
IL
Israel
Prior art keywords
formula
compound
aspects
cps
mosm
Prior art date
Application number
IL325309A
Other languages
English (en)
Hebrew (he)
Inventor
Tim Grinstead
J Gregory Reid
Hoi Lun Allan Tse
Original Assignee
Visus Therapeutics Inc
Tim Grinstead
J Gregory Reid
Hoi Lun Allan Tse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visus Therapeutics Inc, Tim Grinstead, J Gregory Reid, Hoi Lun Allan Tse filed Critical Visus Therapeutics Inc
Publication of IL325309A publication Critical patent/IL325309A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL325309A 2023-06-16 2024-06-14 Synthesis of 2-(carbamoyoxy)-n,n,n-trimethylethan-1-aminium salts IL325309A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363508601P 2023-06-16 2023-06-16
PCT/US2024/034043 WO2024259258A2 (en) 2023-06-16 2024-06-14 Synthesis of 2-(carbamoyloxy)-n,n,n-trimethylethan-1-aminium salts

Publications (1)

Publication Number Publication Date
IL325309A true IL325309A (en) 2026-02-01

Family

ID=93852772

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325309A IL325309A (en) 2023-06-16 2024-06-14 Synthesis of 2-(carbamoyoxy)-n,n,n-trimethylethan-1-aminium salts

Country Status (7)

Country Link
EP (1) EP4727533A2 (de)
KR (1) KR20260023579A (de)
CN (1) CN121548413A (de)
AU (1) AU2024303954A1 (de)
CO (1) CO2026000384A2 (de)
IL (1) IL325309A (de)
WO (1) WO2024259258A2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE129348T1 (de) * 1989-10-13 1995-11-15 Biocompatibles Ltd Verfahren zur verminderung der absetzung von proteinen auf ophthalmologische geräte.
EP3522873B1 (de) * 2016-10-04 2022-03-16 Cellix Bio Private Limited Zusammensetzungen und verfahren zur behandlung von xerostomie

Also Published As

Publication number Publication date
KR20260023579A (ko) 2026-02-20
CO2026000384A2 (es) 2026-02-02
WO2024259258A3 (en) 2025-06-12
AU2024303954A1 (en) 2026-01-29
WO2024259258A2 (en) 2024-12-19
EP4727533A2 (de) 2026-04-22
CN121548413A (zh) 2026-02-17

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