IL324205A - הטרוארילאמידים ביציקליים בעלי פעילות אפנון gpr68 - Google Patents
הטרוארילאמידים ביציקליים בעלי פעילות אפנון gpr68Info
- Publication number
- IL324205A IL324205A IL324205A IL32420525A IL324205A IL 324205 A IL324205 A IL 324205A IL 324205 A IL324205 A IL 324205A IL 32420525 A IL32420525 A IL 32420525A IL 324205 A IL324205 A IL 324205A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- membered
- cycloalkyl
- heterocycloalkyl
- bicyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20230100442 | 2023-06-01 | ||
| GR20240100072 | 2024-02-05 | ||
| PCT/GB2024/051431 WO2024246559A1 (en) | 2023-06-01 | 2024-05-31 | Bicyclic heteroarylamides having gpr68 modulating activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL324205A true IL324205A (he) | 2025-12-01 |
Family
ID=91960610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL324205A IL324205A (he) | 2023-06-01 | 2024-05-31 | הטרוארילאמידים ביציקליים בעלי פעילות אפנון gpr68 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP4720067A1 (he) |
| JP (1) | JP2026518315A (he) |
| KR (1) | KR20260019509A (he) |
| CN (1) | CN121399126A (he) |
| AU (1) | AU2024282839A1 (he) |
| CL (1) | CL2025003739A1 (he) |
| CO (1) | CO2025018379A2 (he) |
| IL (1) | IL324205A (he) |
| MX (1) | MX2025014319A (he) |
| WO (1) | WO2024246559A1 (he) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2670044A1 (en) * | 2006-11-20 | 2008-05-29 | Alantos Pharmaceuticals Holding, Inc. | Heterobicyclic matrix metalloprotease inhibitors |
| CA2672960A1 (en) * | 2006-12-20 | 2008-07-10 | Schering Corporation | Novel jnk inhibitors |
| WO2009002534A1 (en) * | 2007-06-26 | 2008-12-31 | Gilead Colorado, Inc. | Imidazopyridinyl thiazolyl histone deacetylase inhibitors |
-
2024
- 2024-05-31 IL IL324205A patent/IL324205A/he unknown
- 2024-05-31 EP EP24745790.6A patent/EP4720067A1/en active Pending
- 2024-05-31 KR KR1020257042260A patent/KR20260019509A/ko active Pending
- 2024-05-31 WO PCT/GB2024/051431 patent/WO2024246559A1/en not_active Ceased
- 2024-05-31 AU AU2024282839A patent/AU2024282839A1/en active Pending
- 2024-05-31 JP JP2025569751A patent/JP2026518315A/ja active Pending
- 2024-05-31 CN CN202480035787.7A patent/CN121399126A/zh active Pending
-
2025
- 2025-11-27 CL CL2025003739A patent/CL2025003739A1/es unknown
- 2025-11-28 MX MX2025014319A patent/MX2025014319A/es unknown
- 2025-12-22 CO CONC2025/0018379A patent/CO2025018379A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2024282839A1 (en) | 2025-11-13 |
| CN121399126A (zh) | 2026-01-23 |
| JP2026518315A (ja) | 2026-06-04 |
| EP4720067A1 (en) | 2026-04-08 |
| WO2024246559A1 (en) | 2024-12-05 |
| CL2025003739A1 (es) | 2026-02-13 |
| CO2025018379A2 (es) | 2026-01-13 |
| MX2025014319A (es) | 2026-01-07 |
| KR20260019509A (ko) | 2026-02-10 |
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