IL321020A - Methods of administering certain vmat2 inhibitors - Google Patents

Methods of administering certain vmat2 inhibitors

Info

Publication number
IL321020A
IL321020A IL321020A IL32102025A IL321020A IL 321020 A IL321020 A IL 321020A IL 321020 A IL321020 A IL 321020A IL 32102025 A IL32102025 A IL 32102025A IL 321020 A IL321020 A IL 321020A
Authority
IL
Israel
Prior art keywords
vmat2
inhibitor
monoamine transporter
vesicular monoamine
amount
Prior art date
Application number
IL321020A
Other languages
English (en)
Hebrew (he)
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of IL321020A publication Critical patent/IL321020A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL321020A 2019-05-09 2020-05-08 Methods of administering certain vmat2 inhibitors IL321020A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962845599P 2019-05-09 2019-05-09
PCT/US2020/032188 WO2020227672A1 (en) 2019-05-09 2020-05-08 Methods for the administration of certain vmat2 inhibitors

Publications (1)

Publication Number Publication Date
IL321020A true IL321020A (en) 2025-07-01

Family

ID=70919120

Family Applications (2)

Application Number Title Priority Date Filing Date
IL321020A IL321020A (en) 2019-05-09 2020-05-08 Methods of administering certain vmat2 inhibitors
IL287902A IL287902A (en) 2019-05-09 2021-11-08 Methods of administering certain vmat2 inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL287902A IL287902A (en) 2019-05-09 2021-11-08 Methods of administering certain vmat2 inhibitors

Country Status (17)

Country Link
US (2) US20200397779A1 (https=)
EP (1) EP3965764A1 (https=)
JP (2) JP2022531696A (https=)
KR (1) KR20220007105A (https=)
CN (1) CN114340624A (https=)
AU (2) AU2020270145A1 (https=)
BR (1) BR112021020709A2 (https=)
CA (1) CA3136466A1 (https=)
EA (1) EA202193012A1 (https=)
IL (2) IL321020A (https=)
JO (1) JOP20210274A1 (https=)
MA (1) MA55893A (https=)
MX (1) MX2021013132A (https=)
PH (1) PH12021552745A1 (https=)
SG (1) SG11202111465RA (https=)
TW (1) TWI850377B (https=)
WO (1) WO2020227672A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3051830A1 (en) 2017-01-27 2018-08-02 Neurocrine Bioscienes, Inc. Methods for the administration of certain vmat2 inhibitors
CA3076000A1 (en) 2017-09-21 2019-03-28 Neurocrine Biosciences, Inc. High dosage valbenazine formulation and compositions, methods, and kits related thereto
KR20250070134A (ko) 2017-10-10 2025-05-20 뉴로크린 바이오사이언시즈 인코퍼레이티드 특정 vmat2 억제제의 투여 방법
JP2021502959A (ja) 2017-10-10 2021-02-04 ニューロクライン バイオサイエンシーズ,インコーポレイテッド 特定のvmat2インヒビターを投与するための方法
MA53239A (fr) 2018-08-15 2022-05-04 Neurocrine Biosciences Inc Procédés d'administration de certains inhibiteurs de vmat2
CA3220946A1 (en) * 2021-06-30 2023-01-05 Angel S. Angelov Valbenazine for use in the add-on treatment of schizophrenia
TW202322816A (zh) 2021-08-20 2023-06-16 美商紐羅克里生物科學有限公司 篩選 vmat2 抑制劑之方法
EP4489754A1 (en) * 2022-03-07 2025-01-15 Neurocrine Biosciences, Inc. Valbenazine, a vmat2 inhibitor, as a free base a tosylate or ditosylate salt, for use in the treatment of chorea associated with huntington's disease
WO2025038959A1 (en) * 2023-08-17 2025-02-20 Neurocrine Biosciences, Inc. Methods for the administration of certain vmat2 inhibitors
TW202521119A (zh) * 2023-08-17 2025-06-01 美商紐羅克里生物科學有限公司 用於投與特定vmat2抑制劑之方法
WO2025188830A1 (en) * 2024-03-06 2025-09-12 Neurocrine Biosciences, Inc. Methods for the administration of certain vmat2 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US952A (en) 1838-09-27 I antoni bengini
US10065A (en) 1853-10-04 Improvement in machines for topping cotton jn the field
NZ725826A (en) * 2014-05-06 2023-05-26 Neurocrine Biosciences Inc Vmat2 inhibitors for the treatment of hyperkinetic movement disorders
KR20240125709A (ko) * 2015-06-23 2024-08-19 뉴로크린 바이오사이언시즈 인코퍼레이티드 신경계 질환 또는 장애를 치료하기 위한 vmat2 억제제
CA3051830A1 (en) * 2017-01-27 2018-08-02 Neurocrine Bioscienes, Inc. Methods for the administration of certain vmat2 inhibitors
WO2018164996A1 (en) * 2017-03-06 2018-09-13 Neurocrine Biosciences, Inc. Dosing regimen for valbenazine
MA53239A (fr) * 2018-08-15 2022-05-04 Neurocrine Biosciences Inc Procédés d'administration de certains inhibiteurs de vmat2

Also Published As

Publication number Publication date
WO2020227672A1 (en) 2020-11-12
TW202108138A (zh) 2021-03-01
JOP20210274A1 (ar) 2023-01-30
US20200397779A1 (en) 2020-12-24
MA55893A (fr) 2022-03-16
PH12021552745A1 (en) 2022-07-11
AU2025256123A1 (en) 2025-11-13
EA202193012A1 (ru) 2022-03-02
MX2021013132A (es) 2021-11-25
US20220040169A1 (en) 2022-02-10
CN114340624A (zh) 2022-04-12
JP2025013963A (ja) 2025-01-28
BR112021020709A2 (pt) 2021-12-14
CA3136466A1 (en) 2020-11-12
KR20220007105A (ko) 2022-01-18
AU2020270145A1 (en) 2021-12-23
EP3965764A1 (en) 2022-03-16
IL287902A (en) 2022-01-01
SG11202111465RA (en) 2021-11-29
JP2022531696A (ja) 2022-07-08
TWI850377B (zh) 2024-08-01

Similar Documents

Publication Publication Date Title
IL321020A (en) Methods of administering certain vmat2 inhibitors
FI3936130T3 (fi) Valbenatsiinin annostusohjelma hyperkineettisten liikehäiriöiden hoitoon
JP2021098727A5 (https=)
US10857118B2 (en) Compositions and methods for treating intestinal hyperpermeability
Ghoneim et al. Comparison of four opioid analgesics as supplements to nitrous oxide anesthesia
PH12020550237A1 (en) Methods for the administration of certain vmat2 inhibitors
CA2515293A1 (en) Eicosapentaenoic acid for use in improving prognosis in the treatment of subarachnoid hemorrhage
JPH11199477A (ja) 肝臓疾患のための医薬処方
JP2022531696A5 (https=)
CN113893239A (zh) 用于治疗肠渗透性过高的酪氨酸羟化酶抑制剂
HRP20241729T1 (hr) Postupci za liječenje zatajenja srca s aktivatorima srčanih sarkomera
US20220265559A1 (en) Delayed release deferiprone tablets and methods of using the same
RU2017114933A (ru) Соединения и композиции для лечения или профилактики патологических состояний, связанных с избыточным отложением фибрина и/или образованием тромбов
Motwani et al. Clinical pharmacokinetics of drugs administered buccally and sublingually
HRP20230696T1 (hr) Liječenje hereditarnog angioedema
JP2018529742A5 (https=)
RU2012121185A (ru) Фармацевтические композиции комбинаций ингибиторов дипептидилпептидазы-4 с пиоглитазоном
CA3083596A1 (en) Compositions and methods relating to salts of specialized pro-resolving mediators
US20140296274A1 (en) Treatment of pain using a composition of opioid/Toll-like receptor 4 antagonists and dextro enantiomers thereof
JP2018039810A5 (https=)
MX2023002649A (es) Nueva formulacion de acido gamma-aminobutirico.
IL294601A (en) Methods of administration of nalbuphine
US9226924B2 (en) Methods of treating or preventing neuropathic pain
RU2018104691A (ru) Композиции с модифицированным высвобождением ницерголина
US20100062987A1 (en) Anticonvulsive pharmaceutical compositions