IL320391A - Modulators and uses thereof - Google Patents

Modulators and uses thereof

Info

Publication number
IL320391A
IL320391A IL320391A IL32039125A IL320391A IL 320391 A IL320391 A IL 320391A IL 320391 A IL320391 A IL 320391A IL 32039125 A IL32039125 A IL 32039125A IL 320391 A IL320391 A IL 320391A
Authority
IL
Israel
Prior art keywords
smc
modulator
retinal
disease
ccr1
Prior art date
Application number
IL320391A
Other languages
English (en)
Hebrew (he)
Original Assignee
Hadasit Med Res Service
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Med Res Service filed Critical Hadasit Med Res Service
Publication of IL320391A publication Critical patent/IL320391A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL320391A 2022-10-24 2023-10-24 Modulators and uses thereof IL320391A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263380675P 2022-10-24 2022-10-24
PCT/IL2023/051103 WO2024089691A1 (fr) 2022-10-24 2023-10-24 Modulateurs et leurs utilisations

Publications (1)

Publication Number Publication Date
IL320391A true IL320391A (en) 2025-06-01

Family

ID=90830247

Family Applications (1)

Application Number Title Priority Date Filing Date
IL320391A IL320391A (en) 2022-10-24 2023-10-24 Modulators and uses thereof

Country Status (3)

Country Link
EP (1) EP4608403A4 (fr)
IL (1) IL320391A (fr)
WO (1) WO2024089691A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1248968A (zh) * 1997-02-26 2000-03-29 辉瑞大药厂 杂芳基－己酸酰胺衍生物、其制备方法及其作为MIP－1α与其CCRI受体结合的选择性抑制剂的用途
US9314450B2 (en) * 2011-01-11 2016-04-19 Dimerix Bioscience Pty Ltd. Combination therapy
CN103357017B (zh) * 2013-03-07 2015-06-10 首都医科大学附属北京同仁医院 met-RANTES在制备治疗遗传性视网膜变性药物中的应用
CN112386696A (zh) * 2019-08-13 2021-02-23 贵州百灵企业集团制药股份有限公司 一种治疗胰岛素抵抗的靶点及其应用
WO2022079322A1 (fr) * 2020-10-16 2022-04-21 Fundació Centre De Regulació Genòmica Thérapie pour lutter contre une maladie dégénérative et un dommage tissulaire

Also Published As

Publication number Publication date
EP4608403A1 (fr) 2025-09-03
WO2024089691A1 (fr) 2024-05-02
EP4608403A4 (fr) 2026-04-01

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