IL316209A - MODIFIED NK-92 haNK003 CELLS FOR THE CLINIC - Google Patents
MODIFIED NK-92 haNK003 CELLS FOR THE CLINICInfo
- Publication number
- IL316209A IL316209A IL316209A IL31620924A IL316209A IL 316209 A IL316209 A IL 316209A IL 316209 A IL316209 A IL 316209A IL 31620924 A IL31620924 A IL 31620924A IL 316209 A IL316209 A IL 316209A
- Authority
- IL
- Israel
- Prior art keywords
- cells
- modified
- hank003
- cell
- irradiated
- Prior art date
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| PCT/US2018/021332 WO2018165291A1 (en) | 2017-03-08 | 2018-03-07 | MODIFIED NK-92 haNK003 CELLS FOR THE CLINIC |
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| AU2018231193B2 (en) | 2017-03-08 | 2021-07-22 | Immunitybio, Inc. | Modified NK-92 haNK003 cells for the clinic |
| CN119752802A (zh) | 2018-08-01 | 2025-04-04 | 南克维斯特公司 | 用于免疫疗法的基因修饰的包含归巢受体或细胞因子和嵌合抗原受体的四顺反子系统 |
| KR102665280B1 (ko) * | 2018-10-31 | 2024-05-10 | 난트퀘스트, 인크. | Cd19-car 발현 nk 세포에 의한 cd19-양성 림프성 악성종양의 제거 |
| EP3886873A1 (en) * | 2018-11-26 | 2021-10-06 | ImmunityBio, Inc. | Il-2 dependent nk-92 cells with stable fc receptor expression |
| WO2020205100A1 (en) * | 2019-03-15 | 2020-10-08 | Nantcell, Inc. | Recombinant eril-15 nk cells |
| KR20220041850A (ko) * | 2019-07-26 | 2022-04-01 | 난트퀘스트, 인크. | 종양 용해를 위한 효과적인 치료 산물로서의 항체 사전 로드된 cd16+nk-92 세포 |
| AU2020387167B2 (en) * | 2019-11-20 | 2024-10-24 | Immunitybio, Inc. | Cell-mediated transient delivery of immune-enhancing molecules into the tumor microenvironment |
| WO2021116913A1 (en) * | 2019-12-09 | 2021-06-17 | Nantkwest, Inc. | Screening of cell clones expressing polygenic transgenes through non-antibiotic dependent positive selection |
| US11230699B2 (en) | 2020-01-28 | 2022-01-25 | Immunitybio, Inc. | Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors |
| AU2021305084A1 (en) | 2020-07-07 | 2023-02-02 | Cancure, Llc | MIC antibodies and binding agents and methods of using the same |
| CA3199435A1 (en) * | 2020-10-26 | 2022-05-05 | Shoreline Biosciences, Inc. | Methods of inducing antibody-dependent cellular cytotoxicity (adcc) using modified natural killer (nk) cells |
| CN114807237A (zh) * | 2022-05-12 | 2022-07-29 | 广东普罗凯融生物医药科技有限公司 | 一种过表达CD16a的NK细胞的制备方法及其应用 |
| WO2024003723A1 (en) * | 2022-06-28 | 2024-01-04 | Cellply S.R.L. | Method for the characterization of products for cell therapy |
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| TW555562B (en) * | 1996-12-27 | 2003-10-01 | Kirin Brewery | Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof |
| CA2289915A1 (en) * | 1997-04-30 | 1998-11-05 | Hans Klingemann | Natural killer cell lines and methods of use |
| US8034332B2 (en) * | 1997-04-30 | 2011-10-11 | Conkwest, Inc. | Interleukin-secreting natural killer cell lines and methods of use |
| EP1007630B1 (en) | 1997-04-30 | 2006-04-19 | Hans Klingemann | Natural killer cell lines and methods of use |
| EP2112162B1 (en) * | 2004-07-10 | 2015-01-14 | Fox Chase Cancer Center | Genetically modified human natural killer cell lines |
| EP2161339A1 (en) * | 2008-08-29 | 2010-03-10 | F. Hoffmann-La Roche Ag | ADCC with modified NK92 cells |
| KR20250009013A (ko) * | 2015-03-27 | 2025-01-16 | 이뮤너티바이오, 인크. | 암의 치료를 위한 유전적으로 변형된 nk-92 세포 및 모노클로날 항체 |
| KR102526538B1 (ko) * | 2015-06-10 | 2023-04-28 | 이뮤너티바이오, 인크. | 암을 치료하기 위한 변형된 nk-92 세포 |
| AU2018231193B2 (en) | 2017-03-08 | 2021-07-22 | Immunitybio, Inc. | Modified NK-92 haNK003 cells for the clinic |
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2019
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2020
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2021
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2022
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2023
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