IL310877A - Discovery platform - Google Patents

Discovery platform

Info

Publication number
IL310877A
IL310877A IL310877A IL31087724A IL310877A IL 310877 A IL310877 A IL 310877A IL 310877 A IL310877 A IL 310877A IL 31087724 A IL31087724 A IL 31087724A IL 310877 A IL310877 A IL 310877A
Authority
IL
Israel
Prior art keywords
model
treatment
embeddings
interest
placebo
Prior art date
Application number
IL310877A
Other languages
English (en)
Hebrew (he)
Inventor
Francesco Paolo Casale
Michael Bereket
Matthew Albert
Original Assignee
Insitro Inc
Francesco Paolo Casale
Michael Bereket
Matthew Albert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insitro Inc, Francesco Paolo Casale, Michael Bereket, Matthew Albert filed Critical Insitro Inc
Publication of IL310877A publication Critical patent/IL310877A/en

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4848Monitoring or testing the effects of treatment, e.g. of medication
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00Machine learning
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H15/00ICT specially adapted for medical reports, e.g. generation or transmission thereof
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00ICT specially adapted for the handling or processing of medical images
    • G16H30/20ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Pathology (AREA)
  • Databases & Information Systems (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Quality & Reliability (AREA)
  • Software Systems (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Artificial Intelligence (AREA)
  • Mathematical Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Evolutionary Computation (AREA)
  • Image Analysis (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
IL310877A 2021-08-16 2022-08-16 Discovery platform IL310877A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163233707P 2021-08-16 2021-08-16
PCT/US2022/075006 WO2023023507A1 (en) 2021-08-16 2022-08-16 Discovery platform

Publications (1)

Publication Number Publication Date
IL310877A true IL310877A (en) 2024-04-01

Family

ID=83271147

Family Applications (1)

Application Number Title Priority Date Filing Date
IL310877A IL310877A (en) 2021-08-16 2022-08-16 Discovery platform

Country Status (8)

Country Link
US (4) US12002559B2 (https=)
EP (1) EP4388549A1 (https=)
JP (1) JP2024534035A (https=)
KR (1) KR20240068638A (https=)
AU (1) AU2022328586A1 (https=)
CA (1) CA3228785A1 (https=)
IL (1) IL310877A (https=)
WO (1) WO2023023507A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240068638A (ko) 2021-08-16 2024-05-17 인시트로, 인코포레이티드 발견 플랫폼
WO2023092108A2 (en) 2021-11-19 2023-05-25 Insitro, Inc. Autonomous cell imaging and modeling system
US12354013B2 (en) * 2022-05-03 2025-07-08 Salesforce, Inc. Systems and methods for masked self-training of unsupervised image classification
CN115762796A (zh) * 2022-09-27 2023-03-07 京东方科技集团股份有限公司 目标模型的获取方法、预后评估值确定方法、装置、设备及介质
WO2024173610A1 (en) 2023-02-15 2024-08-22 Insitro, Inc. Machine-learning-enabled predictive biomarker discovery and patient stratification using standard-of-care data
CN121175758A (zh) * 2023-03-03 2025-12-19 豪夫迈·罗氏有限公司 用于生物标志物检测的系统和方法
WO2025190827A1 (en) * 2024-03-15 2025-09-18 Bayer Aktiengesellschaft Generation of a synthetic medical image
EP4618009A1 (en) * 2024-03-15 2025-09-17 Bayer Aktiengesellschaft Generation of a synthetic medical image

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US255924A (en) 1882-04-04 Corset
JP4932703B2 (ja) 2005-03-22 2012-05-16 株式会社メディネット 細胞培養評価システム、細胞培養評価方法および細胞培養評価プログラム
CN102272795B (zh) * 2009-01-13 2014-09-10 皇家飞利浦电子股份有限公司 基于图像的临床试验评估
US20170204359A1 (en) 2014-12-19 2017-07-20 Panasonic Corporation Cell culture apparatus
US10467754B1 (en) 2017-02-15 2019-11-05 Google Llc Phenotype analysis of cellular image data using a deep metric network
CN110546277B (zh) 2017-03-01 2024-06-11 豪夫迈·罗氏有限公司 用于癌症的诊断和治疗方法
US11107583B2 (en) * 2018-03-20 2021-08-31 Case Western Reserve University Sequential integration of adversarial networks with handcrafted features (SANwicH): identifying sites of prognostic significance for predicting cancer recurrence
JP7455757B2 (ja) 2018-04-13 2024-03-26 フリーノーム・ホールディングス・インコーポレイテッド 生体試料の多検体アッセイのための機械学習実装
US10957041B2 (en) 2018-05-14 2021-03-23 Tempus Labs, Inc. Determining biomarkers from histopathology slide images
US11955241B2 (en) * 2018-06-03 2024-04-09 The Regents Of The University Of California Pathogenic biomarkers and serum extracellular vesicular biomarkers associated with vascular malformation of endothelial cells, and uses thereof
WO2020010163A1 (en) 2018-07-02 2020-01-09 Tempus Labs, Inc. 3d radiomic platform for imaging biomarker development
EP3857564A1 (en) * 2018-09-29 2021-08-04 F. Hoffmann-La Roche AG Multimodal machine learning based clinical predictor
US20200388287A1 (en) 2018-11-13 2020-12-10 CurieAI, Inc. Intelligent health monitoring
JP7462632B2 (ja) 2018-11-30 2024-04-05 カリス エムピーアイ インコーポレイテッド 次世代分子プロファイリング
US20220059240A1 (en) 2018-12-31 2022-02-24 Tempus Labs, Inc. Method and process for predicting and analyzing patient cohort response, progression, and survival
US12118715B2 (en) 2019-02-01 2024-10-15 Owkin, Inc. Systems and methods for image classification
CA3145370A1 (en) 2019-06-25 2020-12-30 Owkin Inc. Systems and methods for mesothelioma feature detection and enhanced prognosis or response to treatment
WO2020261183A1 (en) 2019-06-25 2020-12-30 Owkin Inc. Systems and methods for image preprocessing
US12230399B2 (en) 2019-09-27 2025-02-18 The Brigham And Women's Hospital, Inc. Multimodal fusion for diagnosis, prognosis, and therapeutic response prediction
EP4070232A4 (en) 2019-12-05 2024-01-31 Tempus Labs, Inc. SYSTEMS AND METHODS FOR HIGH-THROUGHPUT ACTIVE SCREENING
EP4097636A1 (en) 2020-01-28 2022-12-07 PAIGE.AI, Inc. Systems and methods for processing electronic images for computational detection methods
EP3872711A1 (en) 2020-02-28 2021-09-01 Sensyne Health Group Limited Semi-supervised machine learning method and system suitable for identification of patient subgroups in electronic healthcare records
WO2021205033A1 (en) 2020-04-10 2021-10-14 Koninklijke Philips N.V. Clinically meaningful and personalized disease progression monitoring incorporating established disease staging definitions
US12468952B2 (en) 2020-06-02 2025-11-11 Salesforce, Inc. Systems and methods for noise-robust contrastive learning
EP4211657B1 (en) 2020-09-08 2024-12-11 Insitro, Inc. Biological image transformation using machine-learning models
US12271832B2 (en) 2021-02-12 2025-04-08 Tempus Ai, Inc. Artificial intelligence engine for directed hypothesis generation and ranking
US12361542B2 (en) 2021-03-03 2025-07-15 Tempus Ai, Inc. Systems and methods for deep orthogonal fusion for multimodal prognostic biomarker discovery
JP2023015674A (ja) 2021-07-20 2023-02-01 株式会社エビデント 細胞塊の内部予測方法、プログラム、及び、画像処理装置
WO2023009870A1 (en) 2021-07-29 2023-02-02 Tempus Labs, Inc. Platform for co-culture imaging to characterize in vitro efficacy of heterotypic effector cellular therapies in cancer
KR20240068638A (ko) 2021-08-16 2024-05-17 인시트로, 인코포레이티드 발견 플랫폼
WO2023092108A2 (en) 2021-11-19 2023-05-25 Insitro, Inc. Autonomous cell imaging and modeling system
WO2024173610A1 (en) 2023-02-15 2024-08-22 Insitro, Inc. Machine-learning-enabled predictive biomarker discovery and patient stratification using standard-of-care data

Also Published As

Publication number Publication date
AU2022328586A1 (en) 2024-02-29
US20240274255A1 (en) 2024-08-15
WO2023023507A1 (en) 2023-02-23
US20250259723A1 (en) 2025-08-14
US12260946B2 (en) 2025-03-25
KR20240068638A (ko) 2024-05-17
US20230360758A1 (en) 2023-11-09
US20240274254A1 (en) 2024-08-15
CA3228785A1 (en) 2023-02-23
JP2024534035A (ja) 2024-09-18
US12260945B2 (en) 2025-03-25
US12002559B2 (en) 2024-06-04
EP4388549A1 (en) 2024-06-26

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