IL300252A - Modified anti-MUC1 antibodies and their uses - Google Patents
Modified anti-MUC1 antibodies and their usesInfo
- Publication number
- IL300252A IL300252A IL300252A IL30025223A IL300252A IL 300252 A IL300252 A IL 300252A IL 300252 A IL300252 A IL 300252A IL 30025223 A IL30025223 A IL 30025223A IL 300252 A IL300252 A IL 300252A
- Authority
- IL
- Israel
- Prior art keywords
- antibody
- cells
- consensus sequence
- seq
- peptide
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063058044P | 2020-07-29 | 2020-07-29 | |
| US202063122234P | 2020-12-07 | 2020-12-07 | |
| US202163151380P | 2021-02-19 | 2021-02-19 | |
| US202163173083P | 2021-04-09 | 2021-04-09 | |
| US202163184724P | 2021-05-05 | 2021-05-05 | |
| PCT/US2021/071017 WO2022027039A1 (en) | 2020-07-29 | 2021-07-27 | Anti-variable muc1* antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL300252A true IL300252A (en) | 2023-03-01 |
Family
ID=80036184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL300252A IL300252A (en) | 2020-07-29 | 2021-07-27 | Modified anti-MUC1 antibodies and their uses |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4188959A1 (ko) |
| JP (1) | JP2023537326A (ko) |
| KR (1) | KR20230059789A (ko) |
| CN (1) | CN116234828A (ko) |
| AU (1) | AU2021316042A1 (ko) |
| CA (1) | CA3187555A1 (ko) |
| IL (1) | IL300252A (ko) |
| WO (1) | WO2022027039A1 (ko) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7137696B2 (ja) | 2019-05-14 | 2022-09-14 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を予防するための方法および組成物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107660213B (zh) * | 2015-02-10 | 2023-01-13 | 米纳瓦生物技术公司 | 人源化抗MUCl＊抗体 |
| WO2020146902A2 (en) * | 2019-01-11 | 2020-07-16 | Minerva Biotechnologies Corporation | Anti-variable muc1* antibodies and uses thereof |
-
2021
- 2021-07-27 JP JP2023506494A patent/JP2023537326A/ja active Pending
- 2021-07-27 EP EP21850106.2A patent/EP4188959A1/en active Pending
- 2021-07-27 WO PCT/US2021/071017 patent/WO2022027039A1/en unknown
- 2021-07-27 CA CA3187555A patent/CA3187555A1/en active Pending
- 2021-07-27 KR KR1020237006591A patent/KR20230059789A/ko unknown
- 2021-07-27 CN CN202180067049.7A patent/CN116234828A/zh active Pending
- 2021-07-27 IL IL300252A patent/IL300252A/en unknown
- 2021-07-27 AU AU2021316042A patent/AU2021316042A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021316042A1 (en) | 2023-03-30 |
| KR20230059789A (ko) | 2023-05-03 |
| EP4188959A1 (en) | 2023-06-07 |
| CA3187555A1 (en) | 2022-02-03 |
| JP2023537326A (ja) | 2023-08-31 |
| WO2022027039A1 (en) | 2022-02-03 |
| CN116234828A (zh) | 2023-06-06 |
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