IL298796A - Methods and preparations for the prevention and treatment of myopia (myopia) with levocevastine, a selective antagonist of the H1-histamine receptor, and its derivatives - Google Patents

Methods and preparations for the prevention and treatment of myopia (myopia) with levocevastine, a selective antagonist of the H1-histamine receptor, and its derivatives

Info

Publication number
IL298796A
IL298796A IL298796A IL29879622A IL298796A IL 298796 A IL298796 A IL 298796A IL 298796 A IL298796 A IL 298796A IL 29879622 A IL29879622 A IL 29879622A IL 298796 A IL298796 A IL 298796A
Authority
IL
Israel
Prior art keywords
myopia
subject
composition
age
years
Prior art date
Application number
IL298796A
Other languages
English (en)
Hebrew (he)
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of IL298796A publication Critical patent/IL298796A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/451Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL298796A 2020-06-02 2021-06-02 Methods and preparations for the prevention and treatment of myopia (myopia) with levocevastine, a selective antagonist of the H1-histamine receptor, and its derivatives IL298796A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063033291P 2020-06-02 2020-06-02
PCT/US2021/035344 WO2021247635A1 (fr) 2020-06-02 2021-06-02 Méthodes et compositions pour la prévention et le traitement de la myopie avec de la lévocabastine, un antagoniste sélectif du récepteur h1 de l'histamine et des dérivés de celui-ci

Publications (1)

Publication Number Publication Date
IL298796A true IL298796A (en) 2023-02-01

Family

ID=78829881

Family Applications (1)

Application Number Title Priority Date Filing Date
IL298796A IL298796A (en) 2020-06-02 2021-06-02 Methods and preparations for the prevention and treatment of myopia (myopia) with levocevastine, a selective antagonist of the H1-histamine receptor, and its derivatives

Country Status (7)

Country Link
EP (1) EP4157453A4 (fr)
JP (1) JP2023529374A (fr)
KR (1) KR20230051130A (fr)
CN (1) CN115835905A (fr)
CA (1) CA3181292A1 (fr)
IL (1) IL298796A (fr)
WO (1) WO2021247635A1 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2399555B1 (fr) * 2009-02-20 2016-12-07 Seed Co., Ltd. Lentille de contact en hydrogel à libération prolongée de médicament et procédé de libération de médicament mettant en oeuvre une lentille de contact en hydrogel à libération prolongée de médicament
US9827250B2 (en) * 2012-07-31 2017-11-28 Johnson & Johnson Vision Care, Inc. Lens incorporating myopia control optics and muscarinic agents
ITUB20160876A1 (it) * 2016-02-19 2017-08-19 Dambrosio Enzo Maria Combinazione di un agente antiallergico con un antagonista muscarinico e/o un agonista dopaminergico per l'uso in prevenzione/ arresto di miopia assiale nell’uomo
US10945980B2 (en) * 2016-06-21 2021-03-16 The University Of Newcastle Treatment for myopia
KR20200007769A (ko) * 2017-02-21 2020-01-22 싱가포르 헬스 서비시즈 피티이 엘티디 아트로핀을 포함하는 근시의 발병을 방지 또는 지연하기 위한 조성물 및 방법
WO2019104191A1 (fr) * 2017-11-21 2019-05-31 Sydnexis, Inc. Composition ophtalmique et dispositif d'administration associé

Also Published As

Publication number Publication date
EP4157453A4 (fr) 2024-06-19
KR20230051130A (ko) 2023-04-17
CN115835905A (zh) 2023-03-21
EP4157453A1 (fr) 2023-04-05
JP2023529374A (ja) 2023-07-10
CA3181292A1 (fr) 2021-12-09
WO2021247635A1 (fr) 2021-12-09

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