IL298678A - Modified semaphorin 3a, compositions comprising the same and uses thereof - Google Patents

Modified semaphorin 3a, compositions comprising the same and uses thereof

Info

Publication number
IL298678A
IL298678A IL298678A IL29867822A IL298678A IL 298678 A IL298678 A IL 298678A IL 298678 A IL298678 A IL 298678A IL 29867822 A IL29867822 A IL 29867822A IL 298678 A IL298678 A IL 298678A
Authority
IL
Israel
Prior art keywords
modified
sema3a
semaphorin
polypeptide
cells
Prior art date
Application number
IL298678A
Other languages
English (en)
Hebrew (he)
Original Assignee
Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel
Technion Res & Dev Foundation
The Chancellor Masters And Scholars Of The Univ Of Oxford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel, Technion Res & Dev Foundation, The Chancellor Masters And Scholars Of The Univ Of Oxford filed Critical Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel
Publication of IL298678A publication Critical patent/IL298678A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL298678A 2020-06-04 2021-06-03 Modified semaphorin 3a, compositions comprising the same and uses thereof IL298678A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063034476P 2020-06-04 2020-06-04
PCT/IL2021/050660 WO2021245670A1 (en) 2020-06-04 2021-06-03 Modified semaphorin 3a, compositions comprising the same and uses thereof

Publications (1)

Publication Number Publication Date
IL298678A true IL298678A (en) 2023-01-01

Family

ID=78830160

Family Applications (1)

Application Number Title Priority Date Filing Date
IL298678A IL298678A (en) 2020-06-04 2021-06-03 Modified semaphorin 3a, compositions comprising the same and uses thereof

Country Status (8)

Country Link
US (1) US20230272020A1 (https=)
EP (1) EP4161659A4 (https=)
JP (1) JP2023532415A (https=)
CN (1) CN115916351A (https=)
AU (1) AU2021284697A1 (https=)
CA (1) CA3185618A1 (https=)
IL (1) IL298678A (https=)
WO (1) WO2021245670A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115947817B (zh) * 2023-02-22 2024-07-02 甘肃中肽生物科技有限公司 一种肿瘤相关多肽及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
GB9912350D0 (en) * 1999-05-26 1999-07-28 European Molecular Biology Lab Embl Modified cytokine
FI117667B (fi) * 2001-07-05 2007-01-15 Univ Zuerich Farmaseuttinen koostumus, joka soveltuu käytettäväksi ortopediassa ja hammaslääketieteessä
AU2012212047A1 (en) * 2011-02-03 2013-08-22 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
WO2014199364A1 (en) * 2013-06-13 2014-12-18 Bnai Zion Medical Center Semaphorin 3a for treatment and prognosis of systemic lupus erythematosus
RU2722832C2 (ru) * 2015-02-23 2020-06-04 Сигалл Терапьютикс Сас Неприродные семафорины класса 3 и их медицинское применение

Also Published As

Publication number Publication date
WO2021245670A1 (en) 2021-12-09
AU2021284697A1 (en) 2023-01-19
CA3185618A1 (en) 2021-12-09
US20230272020A1 (en) 2023-08-31
CN115916351A (zh) 2023-04-04
EP4161659A4 (en) 2024-03-06
EP4161659A1 (en) 2023-04-12
JP2023532415A (ja) 2023-07-28

Similar Documents

Publication Publication Date Title
KR102302392B1 (ko) 항염증 활성을 갖는 펩티드 및 이를 포함하는 조성물
CN106659757B (zh) 白介素2的超级激动剂、部分激动剂和拮抗剂
JP2021508252A (ja) インターロイキン−2の部分アゴニスト
CN110357953B (zh) 识别人巨细胞病毒pp65抗原的TCR
WO2001019999A1 (en) A GENE ENCODING A NOVEL THREONYL-tRNA SYNTHETASE, ITS USES AND THE PREPARING METHODS
US20250270272A1 (en) Methods of treating multiple sclerosis using autologous t cells
EP1019502A2 (en) Human orphan receptor ntr-1
EP4310188A1 (en) Gene coding for chimeric receptor for anti-acetylcholine receptor autoantibody
EP4010006B1 (en) Hla-dr/cii peptide complexes for treating arthritis
US20230272020A1 (en) Modified semaphorin 3a, compositions comprising the same and uses thereof
Daub et al. Expression of members of the S100 Ca2+-binding protein family in guinea-pig smooth muscle
KR20240128579A (ko) Cd38 또는 이의 단편을 포함하는 자가면역질환 치료용 조성물
US9943567B2 (en) Method for treating arthritis using IK factor or nucleic acid encoding IK factor
CN120019146A (zh) 通用t细胞和组合物及它们的使用方法
AU6176696A (en) Interleukin-1 receptor-associated protein kinase and assays
EP2032601B1 (en) Peptides regulating the surface expression of the t cell receptor
US20140051647A1 (en) Synthetic peptide that induces expression of tnf receptor 2 and use thereof
CN115141268B (zh) 抗炎cd209多肽片段及其抗脂肪性肝病炎症的应用
CN112538108B (zh) 高亲和pvr突变体
JP2001509015A (ja) ヒト塩素イオンチャネルタンパク質(hccp)
EP4667486A1 (en) Composition comprising cd38 or fragment thereof for treating autoimmune diseases
EP2140000A1 (en) Method of enhancing migration of neural precursor cells
US6908765B1 (en) Polypeptide—human SR splicing factor 52 and a polynucleotide encoding the same
HK40103877A (en) Gene coding for chimeric receptor for anti-acetylcholine receptor autoantibody
HK40126591A (zh) 通用t细胞和组合物及它们的使用方法