IL298540A - Device and method for fluid optimization and contaminant containment using a replaceable plug - Google Patents
Device and method for fluid optimization and contaminant containment using a replaceable plugInfo
- Publication number
- IL298540A IL298540A IL298540A IL29854022A IL298540A IL 298540 A IL298540 A IL 298540A IL 298540 A IL298540 A IL 298540A IL 29854022 A IL29854022 A IL 29854022A IL 298540 A IL298540 A IL 298540A
- Authority
- IL
- Israel
- Prior art keywords
- blood
- fluid
- sample
- outlet
- inlet
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title claims description 214
- 239000000356 contaminant Substances 0.000 title claims description 96
- 238000005457 optimization Methods 0.000 title claims description 90
- 238000000034 method Methods 0.000 title description 18
- 239000000463 material Substances 0.000 claims description 67
- 210000004369 blood Anatomy 0.000 description 554
- 239000008280 blood Substances 0.000 description 554
- 230000009919 sequestration Effects 0.000 description 379
- 239000000523 sample Substances 0.000 description 203
- 239000003570 air Substances 0.000 description 200
- 238000005070 sampling Methods 0.000 description 153
- 230000004888 barrier function Effects 0.000 description 108
- 230000037361 pathway Effects 0.000 description 42
- 238000010241 blood sampling Methods 0.000 description 37
- 230000007246 mechanism Effects 0.000 description 27
- 238000009640 blood culture Methods 0.000 description 24
- 230000036772 blood pressure Effects 0.000 description 22
- 230000001681 protective effect Effects 0.000 description 18
- 238000007789 sealing Methods 0.000 description 18
- 239000012528 membrane Substances 0.000 description 16
- 238000011109 contamination Methods 0.000 description 15
- 238000013022 venting Methods 0.000 description 15
- 230000002209 hydrophobic effect Effects 0.000 description 13
- 238000012360 testing method Methods 0.000 description 12
- 230000017531 blood circulation Effects 0.000 description 11
- 238000006073 displacement reaction Methods 0.000 description 11
- 244000052769 pathogen Species 0.000 description 10
- 210000003491 skin Anatomy 0.000 description 10
- 230000002792 vascular Effects 0.000 description 10
- 230000000007 visual effect Effects 0.000 description 9
- 229920001971 elastomer Polymers 0.000 description 8
- 239000004033 plastic Substances 0.000 description 8
- 229920003023 plastic Polymers 0.000 description 8
- 210000001124 body fluid Anatomy 0.000 description 7
- 238000000576 coating method Methods 0.000 description 7
- 238000004804 winding Methods 0.000 description 7
- 208000031729 Bacteremia Diseases 0.000 description 6
- 206010040047 Sepsis Diseases 0.000 description 6
- 238000004026 adhesive bonding Methods 0.000 description 6
- 239000011248 coating agent Substances 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 230000036961 partial effect Effects 0.000 description 6
- 239000005060 rubber Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 210000003462 vein Anatomy 0.000 description 6
- 238000003466 welding Methods 0.000 description 6
- 239000012080 ambient air Substances 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 239000003292 glue Substances 0.000 description 5
- 230000013011 mating Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 208000032484 Accidental exposure to product Diseases 0.000 description 4
- 231100000818 accidental exposure Toxicity 0.000 description 4
- 238000013459 approach Methods 0.000 description 4
- 230000007613 environmental effect Effects 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 230000003260 anti-sepsis Effects 0.000 description 3
- 238000013037 co-molding Methods 0.000 description 3
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- 230000006835 compression Effects 0.000 description 3
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- 239000013536 elastomeric material Substances 0.000 description 3
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- 238000005530 etching Methods 0.000 description 3
- 238000001746 injection moulding Methods 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 239000003566 sealing material Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 2
- 229920002943 EPDM rubber Polymers 0.000 description 2
- 208000012266 Needlestick injury Diseases 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
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- 210000002381 plasma Anatomy 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- 210000002105 tongue Anatomy 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241000272525 Anas platyrhynchos Species 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 241001671865 Erimyzon oblongus Species 0.000 description 1
- 206010017523 Fungaemia Diseases 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 208000001871 Tachycardia Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 description 1
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 238000011203 antimicrobial therapy Methods 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 230000036543 hypotension Effects 0.000 description 1
- 238000009863 impact test Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000001846 repelling effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000007727 signaling mechanism Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 208000008203 tachypnea Diseases 0.000 description 1
- 206010043089 tachypnoea Diseases 0.000 description 1
- 238000012549 training Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150213—Venting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150221—Valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150251—Collection chamber divided into at least two compartments, e.g. for division of samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
- A61B5/150572—Pierceable protectors, e.g. shields, caps, sleeves or films, e.g. for hygienic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150992—Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; Blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings or valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
- A61B5/154—Devices using pre-evacuated means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Manufacturing & Machinery (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Sampling And Sample Adjustment (AREA)
- Cleaning In General (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063033196P | 2020-06-01 | 2020-06-01 | |
| PCT/US2021/035294 WO2021247609A1 (en) | 2020-06-01 | 2021-06-01 | Fluid optimization and contaminant containment device and method using displaceable plug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL298540A true IL298540A (en) | 2023-01-01 |
Family
ID=78829865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL298540A IL298540A (en) | 2020-06-01 | 2021-06-01 | Device and method for fluid optimization and contaminant containment using a replaceable plug |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4158303A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2023528372A (cg-RX-API-DMAC7.html) |
| CN (1) | CN115735108A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2021283887A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3185426A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL298540A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2022015161A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2021247609A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118010410B (zh) * | 2024-04-10 | 2024-07-23 | 四川蜀工公路工程试验检测有限公司 | 混凝土钻孔取芯机 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006020934A (ja) * | 2004-07-09 | 2006-01-26 | Nipro Corp | 採血針 |
| JP2006239645A (ja) * | 2005-03-07 | 2006-09-14 | Seiko Epson Corp | 液滴吐出装置 |
| US8197420B2 (en) * | 2006-12-18 | 2012-06-12 | Magnolia Medical Technologies, Inc. | Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination |
| JP5793715B2 (ja) * | 2011-04-28 | 2015-10-14 | パナソニックＩｐマネジメント株式会社 | 空気調和装置 |
| JP6376914B2 (ja) * | 2014-09-11 | 2018-08-22 | 藤倉ゴム工業株式会社 | 逆止弁構造 |
| US9820682B2 (en) | 2015-07-24 | 2017-11-21 | Kurin, Inc. | Blood sample optimization system and blood contaminant sequestration device and method |
| JP7273807B2 (ja) * | 2017-06-09 | 2023-05-15 | マグノリア メディカル テクノロジーズ，インコーポレイテッド | 流体制御デバイス及びそれを使用する方法 |
| EP3681384B1 (en) * | 2017-09-12 | 2022-12-28 | Magnolia Medical Technologies, Inc. | A system |
| US11419531B2 (en) * | 2017-12-07 | 2022-08-23 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
| WO2019232196A1 (en) * | 2018-05-31 | 2019-12-05 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
-
2021
- 2021-06-01 MX MX2022015161A patent/MX2022015161A/es unknown
- 2021-06-01 CN CN202180046012.6A patent/CN115735108A/zh active Pending
- 2021-06-01 WO PCT/US2021/035294 patent/WO2021247609A1/en not_active Ceased
- 2021-06-01 JP JP2022572789A patent/JP2023528372A/ja active Pending
- 2021-06-01 CA CA3185426A patent/CA3185426A1/en active Pending
- 2021-06-01 AU AU2021283887A patent/AU2021283887A1/en not_active Abandoned
- 2021-06-01 EP EP21818838.1A patent/EP4158303A4/en active Pending
- 2021-06-01 IL IL298540A patent/IL298540A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3185426A1 (en) | 2021-12-09 |
| EP4158303A4 (en) | 2024-05-22 |
| WO2021247609A1 (en) | 2021-12-09 |
| EP4158303A1 (en) | 2023-04-05 |
| JP2023528372A (ja) | 2023-07-04 |
| AU2021283887A1 (en) | 2023-01-19 |
| MX2022015161A (es) | 2023-03-02 |
| CN115735108A (zh) | 2023-03-03 |
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