IL296531A - שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8 - Google Patents

שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8

Info

Publication number
IL296531A
IL296531A IL296531A IL29653122A IL296531A IL 296531 A IL296531 A IL 296531A IL 296531 A IL296531 A IL 296531A IL 29653122 A IL29653122 A IL 29653122A IL 296531 A IL296531 A IL 296531A
Authority
IL
Israel
Prior art keywords
glioma
methyl
acid
tumo
cancer
Prior art date
Application number
IL296531A
Other languages
English (en)
Original Assignee
Es Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Es Therapeutics Llc filed Critical Es Therapeutics Llc
Publication of IL296531A publication Critical patent/IL296531A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL296531A 2020-03-16 2021-03-15 שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8 IL296531A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062990327P 2020-03-16 2020-03-16
US202063031347P 2020-05-28 2020-05-28
PCT/US2021/022356 WO2021188431A1 (en) 2020-03-16 2021-03-15 Method of treating glioma cancer using tarp gamma 8-dependent ampa receptor antagonists

Publications (1)

Publication Number Publication Date
IL296531A true IL296531A (he) 2022-11-01

Family

ID=77772160

Family Applications (1)

Application Number Title Priority Date Filing Date
IL296531A IL296531A (he) 2020-03-16 2021-03-15 שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8

Country Status (2)

Country Link
IL (1) IL296531A (he)
WO (1) WO2021188431A1 (he)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201609719A (zh) * 2014-05-28 2016-03-16 美國禮來大藥廠 作為TARP-γ8依賴性AMPA受體拮抗劑之6-經取代-3H-1,3-苯并噻唑-2-酮化合物
WO2020023800A1 (en) * 2018-07-27 2020-01-30 With Great Power, Llc Clinical methods and pharmaceutical compositions employing ampa receptor antagonists to treat glioblastoma and other cancers

Also Published As

Publication number Publication date
WO2021188431A1 (en) 2021-09-23

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