IL296531A - שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8 - Google Patents
שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8Info
- Publication number
- IL296531A IL296531A IL296531A IL29653122A IL296531A IL 296531 A IL296531 A IL 296531A IL 296531 A IL296531 A IL 296531A IL 29653122 A IL29653122 A IL 29653122A IL 296531 A IL296531 A IL 296531A
- Authority
- IL
- Israel
- Prior art keywords
- glioma
- methyl
- acid
- tumo
- cancer
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US202062990327P | 2020-03-16 | 2020-03-16 | |
US202063031347P | 2020-05-28 | 2020-05-28 | |
PCT/US2021/022356 WO2021188431A1 (en) | 2020-03-16 | 2021-03-15 | Method of treating glioma cancer using tarp gamma 8-dependent ampa receptor antagonists |
Publications (1)
Publication Number | Publication Date |
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IL296531A true IL296531A (he) | 2022-11-01 |
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ID=77772160
Family Applications (1)
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IL296531A IL296531A (he) | 2020-03-16 | 2021-03-15 | שיטה לטיפול בסרטן גליומה על ידי שימוש באנטגוניסטים לקולטן ampa תלוי tarp גמא 8 |
Country Status (2)
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IL (1) | IL296531A (he) |
WO (1) | WO2021188431A1 (he) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
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TW201609719A (zh) * | 2014-05-28 | 2016-03-16 | 美國禮來大藥廠 | 作為TARP-γ8依賴性AMPA受體拮抗劑之6-經取代-3H-1,3-苯并噻唑-2-酮化合物 |
WO2020023800A1 (en) * | 2018-07-27 | 2020-01-30 | With Great Power, Llc | Clinical methods and pharmaceutical compositions employing ampa receptor antagonists to treat glioblastoma and other cancers |
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2021
- 2021-03-15 WO PCT/US2021/022356 patent/WO2021188431A1/en active Application Filing
- 2021-03-15 IL IL296531A patent/IL296531A/he unknown
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WO2021188431A1 (en) | 2021-09-23 |
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