IL29485A - Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines - Google Patents

Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines

Info

Publication number
IL29485A
IL29485A IL29485A IL2948568A IL29485A IL 29485 A IL29485 A IL 29485A IL 29485 A IL29485 A IL 29485A IL 2948568 A IL2948568 A IL 2948568A IL 29485 A IL29485 A IL 29485A
Authority
IL
Israel
Prior art keywords
benzazepines
tetrahydro
preparation
Prior art date
Application number
IL29485A
Other languages
English (en)
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Publication of IL29485A publication Critical patent/IL29485A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Drawers Of Furniture (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL29485A 1967-02-17 1968-02-16 Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines IL29485A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH1167167A CH488705A (de) 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
IL29485A true IL29485A (en) 1971-07-28

Family

ID=25690322

Family Applications (1)

Application Number Title Priority Date Filing Date
IL29485A IL29485A (en) 1967-02-17 1968-02-16 Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines

Country Status (13)

Country Link
US (1) US3652543A (US07223432-20070529-C00017.png)
AT (1) AT275533B (US07223432-20070529-C00017.png)
BE (1) BE710872A (US07223432-20070529-C00017.png)
CH (2) CH481110A (US07223432-20070529-C00017.png)
DE (2) DE1668915A1 (US07223432-20070529-C00017.png)
DK (1) DK115473B (US07223432-20070529-C00017.png)
ES (1) ES350574A1 (US07223432-20070529-C00017.png)
FR (2) FR1561479A (US07223432-20070529-C00017.png)
GB (2) GB1222397A (US07223432-20070529-C00017.png)
IL (1) IL29485A (US07223432-20070529-C00017.png)
NL (1) NL6802257A (US07223432-20070529-C00017.png)
NO (1) NO124369B (US07223432-20070529-C00017.png)
SE (1) SE342043B (US07223432-20070529-C00017.png)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT289812B (de) * 1968-08-09 1971-05-10 Geigy Ag J R Verfahren zur Herstellung des neuen 2-Methyl-7-chlor-2,3,4,5-tetrahydro-1H-3-benzazepins sowie seiner Säureadditionssalze
DE2016136A1 (de) * 1970-04-04 1971-10-14 C H Boehnnger Sohn, 6507 Ingel heim Neue 7 Acyl 1,2,4,5 tetrahydro (3H) 3 benzazepine
DE2143204C3 (de) * 1971-08-28 1979-09-27 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis
FR2171879A1 (en) * 1972-02-14 1973-09-28 Pennwalt Corp 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
EP0161350A1 (en) * 1981-11-27 1985-11-21 Smithkline Beckman Corporation Process for preparing benzazepines
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
US4973586A (en) * 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
KR900007781B1 (ko) * 1986-01-16 1990-10-20 쉐링 코포레이션 융합된 벤즈아제핀
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
EP0363353B1 (en) * 1987-07-15 1992-07-22 Schering Corporation Fused benzazepines
EP0513174B1 (en) * 1990-02-02 1995-08-16 Schering Corporation 4,5-cycloalkano-3-benzazepin-7-ol-derivatives and their use
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
US20030220661A1 (en) * 2002-05-21 2003-11-27 Heartstent Corporation Transmyocardial implant delivery system
BRPI0411470A (pt) * 2003-06-17 2006-07-11 Arena Pharm Inc derivados de benzazepina úteis para o tratamento de doenças associadas com o receptor de 5ht2c
ES2571220T3 (es) * 2003-06-17 2016-05-24 Arena Pharm Inc Clorhidrato de 8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzazepina
WO2005042490A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
US20080009478A1 (en) * 2003-10-22 2008-01-10 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
ATE442359T1 (de) 2004-12-21 2009-09-15 Arena Pharm Inc Kristalline formen von (r)-8-chlor-1-methyl-2,3,4,5-tetrahydro-1h-3-be zazepinhydrochlorid
NZ555482A (en) 2004-12-23 2011-01-28 Arena Pharm Inc Compositions comprising a 5HT2C receptor modulator and 2-methylamphetamine and methods of use
CN101466684B (zh) * 2006-04-03 2012-06-20 艾尼纳制药公司 8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的制备工艺和其相关中间体
SG177128A1 (en) * 2006-12-05 2012-01-30 Arena Pharm Inc Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
WO2009111004A1 (en) * 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
US8952197B2 (en) 2009-06-18 2015-02-10 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
MX2013002421A (es) 2010-09-01 2013-05-17 Arena Pharm Inc Sales no hidroscopicas de agonistas de 5-ht2c.
AU2011296014A1 (en) 2010-09-01 2013-04-04 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
SG188362A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Modified-release dosage forms of 5-ht2c agonists useful for weight management
EP2611449A1 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Administration of lorcaserin to individuals with renal impairment
CA2886875A1 (en) 2012-10-09 2014-04-17 Arena Pharmaceuticals, Inc. Method of weight management

Also Published As

Publication number Publication date
AT275533B (de) 1969-10-27
GB1221324A (en) 1971-02-03
SE342043B (US07223432-20070529-C00017.png) 1972-01-24
US3652543A (en) 1972-03-28
CH481110A (de) 1969-11-15
NO124369B (US07223432-20070529-C00017.png) 1972-04-10
ES350574A1 (es) 1969-11-16
GB1222397A (en) 1971-02-10
CH488705A (de) 1970-04-15
FR1561479A (US07223432-20070529-C00017.png) 1969-03-28
FR1560654A (US07223432-20070529-C00017.png) 1969-03-21
BE710872A (US07223432-20070529-C00017.png) 1968-08-16
DE1668915A1 (de) 1972-03-09
NL6802257A (US07223432-20070529-C00017.png) 1968-08-19
DE1695124A1 (de) 1970-08-20
DK115473B (da) 1969-10-13

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