IL293504A - שימוש בפותח תעלת אשלגן kv7 לטיפול בכאב - Google Patents
שימוש בפותח תעלת אשלגן kv7 לטיפול בכאבInfo
- Publication number
- IL293504A IL293504A IL293504A IL29350422A IL293504A IL 293504 A IL293504 A IL 293504A IL 293504 A IL293504 A IL 293504A IL 29350422 A IL29350422 A IL 29350422A IL 293504 A IL293504 A IL 293504A
- Authority
- IL
- Israel
- Prior art keywords
- pain
- compound
- human
- dose
- administered
- Prior art date
Links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A61K31/33—Heterocyclic compounds
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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| US201962945093P | 2019-12-06 | 2019-12-06 | |
| US201962948010P | 2019-12-13 | 2019-12-13 | |
| PCT/US2020/063471 WO2021113757A1 (en) | 2019-12-06 | 2020-12-04 | Use of a kv7 potassium channel opener for treating pain |
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| IL293504A true IL293504A (he) | 2022-08-01 |
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| JP (1) | JP2023504166A (he) |
| KR (1) | KR20220113411A (he) |
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| CN113698345B (zh) * | 2021-10-27 | 2022-02-01 | 上海挚盟医药科技有限公司 | 作为钾通道调节剂的化合物及其制备和应用 |
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| US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
| PL2061465T3 (pl) | 2006-08-23 | 2014-03-31 | Valeant Pharmaceuticals Int | Pochodne 4-(N-azacykloalkilo) anilidów jako modulatory kanałów potasowych |
| WO2013067591A1 (en) * | 2011-11-10 | 2013-05-16 | Relevare Australia Pty Ltd | Topical formulations for pain management |
| US9248122B2 (en) * | 2012-11-28 | 2016-02-02 | Grünenthal GmbH | Heteroquinoline-3-carboxamides as KCNQ2/3 modulators |
| DK3790548T3 (da) * | 2018-05-11 | 2023-11-13 | Xenon Pharmaceuticals Inc | Fremgangsmåder til forbedring af biotilgængeligheden og eksponeringen af en åbner af spændingsstyret kaliumkanal |
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Also Published As
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| CA3159436A1 (en) | 2021-06-10 |
| CL2022001477A1 (es) | 2023-04-28 |
| PE20221169A1 (es) | 2022-07-25 |
| MX2022006877A (es) | 2022-07-11 |
| CN114786658A (zh) | 2022-07-22 |
| KR20220113411A (ko) | 2022-08-12 |
| CR20220318A (es) | 2022-10-07 |
| WO2021113757A1 (en) | 2021-06-10 |
| TW202133847A (zh) | 2021-09-16 |
| JP2023504166A (ja) | 2023-02-01 |
| AU2020397173A1 (en) | 2022-06-23 |
| EP4069211A1 (en) | 2022-10-12 |
| BR112022010733A2 (pt) | 2022-08-23 |
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