IL291315A - Stable, concentrated radiopharmaceutical composition - Google Patents

Stable, concentrated radiopharmaceutical composition

Info

Publication number
IL291315A
IL291315A IL291315A IL29131522A IL291315A IL 291315 A IL291315 A IL 291315A IL 291315 A IL291315 A IL 291315A IL 29131522 A IL29131522 A IL 29131522A IL 291315 A IL291315 A IL 291315A
Authority
IL
Israel
Prior art keywords
stable
radiopharmaceutical preparation
concentrated
concentrated radiopharmaceutical
preparation
Prior art date
Application number
IL291315A
Other languages
English (en)
Hebrew (he)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL291315A publication Critical patent/IL291315A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL291315A 2019-09-16 2022-03-13 Stable, concentrated radiopharmaceutical composition IL291315A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19197607 2019-09-16
PCT/EP2020/075767 WO2021052960A1 (en) 2019-09-16 2020-09-15 Stable, concentrated radiopharmaceutical composition

Publications (1)

Publication Number Publication Date
IL291315A true IL291315A (en) 2022-05-01

Family

ID=67981980

Family Applications (1)

Application Number Title Priority Date Filing Date
IL291315A IL291315A (en) 2019-09-16 2022-03-13 Stable, concentrated radiopharmaceutical composition

Country Status (10)

Country Link
US (2) US12685790B2 (cg-RX-API-DMAC7.html)
EP (1) EP4031193A1 (cg-RX-API-DMAC7.html)
JP (2) JP7762648B2 (cg-RX-API-DMAC7.html)
KR (1) KR20220063218A (cg-RX-API-DMAC7.html)
CN (1) CN114728088A (cg-RX-API-DMAC7.html)
AR (1) AR119974A1 (cg-RX-API-DMAC7.html)
AU (1) AU2020349002B2 (cg-RX-API-DMAC7.html)
CA (1) CA3154302A1 (cg-RX-API-DMAC7.html)
IL (1) IL291315A (cg-RX-API-DMAC7.html)
WO (1) WO2021052960A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250032652A1 (en) * 2021-11-30 2025-01-30 Nihon Medi-Physics Co., Ltd. Stabilized radiopharmaceutical composition
CN114404618A (zh) * 2022-03-28 2022-04-29 北京先通国际医药科技股份有限公司 放射性药物水溶液及其用途
CN114404619A (zh) * 2022-03-28 2022-04-29 北京先通国际医药科技股份有限公司 放射性药物水溶液及其制备方法和用途
CN116920129A (zh) * 2022-04-02 2023-10-24 北京先通国际医药科技股份有限公司 放射性药物水溶液及其制备方法和用途
EP4661919A1 (en) 2023-02-08 2025-12-17 Novartis AG Methods for treating glioblastoma
TW202434313A (zh) 2023-02-23 2024-09-01 瑞士商諾華公司 用於治療乳癌之方法
JPWO2025058000A1 (cg-RX-API-DMAC7.html) 2023-09-13 2025-03-20
TW202527951A (zh) 2023-12-15 2025-07-16 瑞士商諾華公司 用於治療乳腺癌的方法
WO2026149506A1 (zh) * 2025-01-10 2026-07-16 天津恒瑞医药有限公司 一种药物组合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3812680B2 (ja) 1994-03-16 2006-08-23 マリンクロッド・インコーポレイテッド 放射性医薬用途のペプチド類およびタンパク質類の安定化
CN100418585C (zh) * 2003-07-24 2008-09-17 伯拉考成像股份公司 稳定的放射性药物组合物及制备方法
WO2008009444A1 (en) 2006-07-19 2008-01-24 Van Dulmen, Adrianus, A. Use of ethanol for stabilizing a single-vial liquid formulation of a radiolabeled peptide
KR102190005B1 (ko) 2012-09-25 2020-12-15 어드밴스드 액셀러레이터 애플리케이션즈 유에스에이, 인코퍼레이티드. Grpr-양성 암의 검출, 진단과 치료를 위한 grpr-길항제
US20150217006A1 (en) 2014-02-06 2015-08-06 Immunomedics, Inc. Al-f-18-labeled, al-f-19-labeled and ga-68-labeled gastrin-releasing peptide receptor (grpr)-antagonists for imaging of prostate cancer
EP3664845A4 (en) 2017-08-08 2021-03-10 Pionyr Immunotherapeutics, Inc. COMPOSITIONS AND METHODS OF DEACTIVATION OF MYELOID CELLS EXPRESSING TREM1

Also Published As

Publication number Publication date
KR20220063218A (ko) 2022-05-17
CA3154302A1 (en) 2021-03-25
WO2021052960A1 (en) 2021-03-25
JP2022548875A (ja) 2022-11-22
EP4031193A1 (en) 2022-07-27
AR119974A1 (es) 2022-01-26
US12685790B2 (en) 2026-07-21
JP2026031934A (ja) 2026-02-25
TW202123976A (zh) 2021-07-01
AU2020349002B2 (en) 2024-05-02
US20250332301A1 (en) 2025-10-30
US20220401593A1 (en) 2022-12-22
AU2020349002A1 (en) 2022-04-28
JP7762648B2 (ja) 2025-10-30
CN114728088A (zh) 2022-07-08

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