IL281937A - Delivery of low surface tension formulations to the pulmonary system using an electronic breath-actuated droplet delivery device - Google Patents
Delivery of low surface tension formulations to the pulmonary system using an electronic breath-actuated droplet delivery deviceInfo
- Publication number
- IL281937A IL281937A IL281937A IL28193721A IL281937A IL 281937 A IL281937 A IL 281937A IL 281937 A IL281937 A IL 281937A IL 28193721 A IL28193721 A IL 28193721A IL 281937 A IL281937 A IL 281937A
- Authority
- IL
- Israel
- Prior art keywords
- delivery
- surface tension
- system via
- low surface
- via electronic
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 230000002685 pulmonary effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
- A61B5/002—Monitoring the patient using a local or closed circuit, e.g. in a room or building
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
- B05B17/0646—Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
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- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
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- A—HUMAN NECESSITIES
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- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0247—Pressure sensors
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- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
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- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
- A61M2021/0022—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/121—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit interface between cassette and base
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
- A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
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- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6009—General characteristics of the apparatus with identification means for matching patient with his treatment, e.g. to improve transfusion security
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/6063—Optical identification systems
- A61M2205/6072—Bar codes
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7536—General characteristics of the apparatus with filters allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
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- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/11—Laminar flow
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- A—HUMAN NECESSITIES
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- A61M2207/00—Methods of manufacture, assembly or production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Computer Networks & Wireless Communication (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862739740P | 2018-10-01 | 2018-10-01 | |
| PCT/US2019/054042 WO2020072478A1 (en) | 2018-10-01 | 2019-10-01 | Delivery of low surface tension compositions to the pulmonary system via electronic breath actuated droplet delivery device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL281937A true IL281937A (en) | 2021-05-31 |
Family
ID=70054758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL281937A IL281937A (en) | 2018-10-01 | 2021-03-31 | Delivery of low surface tension formulations to the pulmonary system using an electronic breath-actuated droplet delivery device |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20220001122A1 (https=) |
| EP (2) | EP4397343A3 (https=) |
| JP (1) | JP2022508519A (https=) |
| CN (1) | CN112996605A (https=) |
| AU (1) | AU2019352957A1 (https=) |
| CA (1) | CA3113981A1 (https=) |
| IL (1) | IL281937A (https=) |
| WO (1) | WO2020072478A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017192773A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency |
| EP3452150B1 (en) * | 2016-05-03 | 2024-01-17 | Pneuma Respiratory, Inc. | Droplet delivery device for delivery of fluids to the pulmonary system |
| EP4624054A3 (en) | 2016-05-03 | 2025-11-19 | Pneuma Respiratory, Inc. | Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device |
| WO2017192774A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device |
| WO2017192782A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
| WO2018213834A1 (en) | 2017-05-19 | 2018-11-22 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
| CN111526914A (zh) | 2017-10-04 | 2020-08-11 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
| EP4344719B1 (en) | 2017-10-17 | 2025-12-31 | Pneuma Respiratory, Inc. | NASAL MEDICATION ADMINISTRATION DEVICE |
| JP2021502178A (ja) | 2017-11-08 | 2021-01-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
| US12501929B2 (en) | 2018-08-22 | 2025-12-23 | Qnovia, Inc. | Electronic device for producing an aerosol for inhalation by a person |
| US11690963B2 (en) | 2018-08-22 | 2023-07-04 | Qnovia, Inc. | Electronic device for producing an aerosol for inhalation by a person |
| CA3110469A1 (en) | 2018-08-22 | 2020-02-27 | Respira Technologies, Inc. | Electronic device for producing an aerosol for inhalation by a person |
| US11517685B2 (en) | 2019-01-18 | 2022-12-06 | Qnovia, Inc. | Electronic device for producing an aerosol for inhalation by a person |
| US20220192535A1 (en) * | 2019-04-15 | 2022-06-23 | Endo Medical, Inc. | Breath analysis device |
| CA3144418A1 (en) * | 2019-06-27 | 2020-12-30 | Pneuma Respiratory, Inc. | Delivery of small droplets to the respiratory system via electronic breath actuated droplet delivery device |
| WO2021262799A1 (en) | 2020-06-23 | 2021-12-30 | Flagship Pioneering, Inc. | Anti-viral compounds and methods of using same |
| WO2022051496A1 (en) | 2020-09-02 | 2022-03-10 | Aculon, Inc. | Methods of altering the surface energy of components of a mesh nebulizer |
| EP4112108B1 (de) * | 2020-09-09 | 2024-11-27 | Pulmotree Medical GmbH | Verneblersystem |
| US12471625B2 (en) | 2020-11-01 | 2025-11-18 | Qnovia, Inc. | Electronic devices and liquids for aerosolizing and inhaling therewith |
| US11793945B2 (en) | 2021-06-22 | 2023-10-24 | Pneuma Respiratory, Inc. | Droplet delivery device with push ejection |
| US20230000150A1 (en) * | 2021-06-30 | 2023-01-05 | Pneuma Respiratory, Inc. | Droplet delivery device with optimized mixing of suspensions |
| US20230310762A1 (en) * | 2022-03-29 | 2023-10-05 | Funai Electric Co., Ltd. | Method of jetting a fluid that is synchronized with breathing |
| US12484618B2 (en) | 2022-04-22 | 2025-12-02 | Qnovia, Inc. | Electronic devices for aerosolizing and inhaling liquid having diaphragm and a pressure sensor |
| CN119768202A (zh) | 2022-07-18 | 2025-04-04 | 精呼吸股份有限公司 | 小步长高分辨率气溶胶生成系统及方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ241034A (en) * | 1990-12-17 | 1995-03-28 | Minnesota Mining & Mfg | Inhaler device with a dosage control that deactivates an aerosol generator after predetermined time or dosage |
| GB2272389B (en) * | 1992-11-04 | 1996-07-24 | Bespak Plc | Dispensing apparatus |
| US6397838B1 (en) * | 1998-12-23 | 2002-06-04 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary aerosol delivery device and method |
| EP1236517A1 (en) * | 2001-02-23 | 2002-09-04 | Microflow Engineering SA | Method of manufacturing a liquid droplet spray device and such spray device |
| JP2006507921A (ja) * | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体分散のための方法および装置 |
| US7849850B2 (en) * | 2003-02-28 | 2010-12-14 | Battelle Memorial Institute | Nozzle for handheld pulmonary aerosol delivery device |
| US20050150489A1 (en) * | 2004-01-12 | 2005-07-14 | Steve Dunfield | Dispensing medicaments based on rates of medicament action |
| US8546423B2 (en) * | 2005-05-18 | 2013-10-01 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
| WO2010008424A2 (en) * | 2008-04-04 | 2010-01-21 | Novartis Ag | Aerosolization device |
| US11247003B2 (en) * | 2010-08-23 | 2022-02-15 | Darren Rubin | Systems and methods of aerosol delivery with airflow regulation |
| US20130172830A1 (en) * | 2011-12-12 | 2013-07-04 | Corinthian Ophthalmic, Inc. | Ejector mechanism, ejector device, and methods of use |
| EP2838669B1 (en) * | 2012-04-20 | 2018-01-03 | Eyenovia, Inc. | Spray ejector device and methods of use |
| US10105500B2 (en) * | 2012-05-09 | 2018-10-23 | Virginia Commonwealth University | Dry powder inhaler (DPI) designs for producing aerosols with high fine particle fractions |
| GB201316314D0 (en) | 2013-09-13 | 2013-10-30 | The Technology Partnership Plc | Fluid management for vibration perforate membrane spray systems |
| KR102624565B1 (ko) | 2015-04-10 | 2024-01-11 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 스위칭가능한 디지털 향기 발생 및 방출, 그리고 증기 및 액체 전달 방법 및 시스템 |
| GB2551944B (en) * | 2015-12-18 | 2021-09-01 | Midatech Pharma Wales Ltd | Microparticle production process and apparatus |
| GB201603823D0 (en) | 2016-03-04 | 2016-04-20 | Univ College Cork Nat Univ Ie | A micro-fabricated mesh device and method of making same |
| EP4624054A3 (en) * | 2016-05-03 | 2025-11-19 | Pneuma Respiratory, Inc. | Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device |
| CN111526914A (zh) * | 2017-10-04 | 2020-08-11 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
| JP2021502178A (ja) * | 2017-11-08 | 2021-01-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
| WO2019219457A1 (en) * | 2018-05-16 | 2019-11-21 | Philip Morris Products S.A. | Atomiser assembly with oscillation chamber |
-
2019
- 2019-10-01 US US17/281,676 patent/US20220001122A1/en not_active Abandoned
- 2019-10-01 AU AU2019352957A patent/AU2019352957A1/en not_active Abandoned
- 2019-10-01 CN CN201980073544.1A patent/CN112996605A/zh active Pending
- 2019-10-01 EP EP24176874.6A patent/EP4397343A3/en active Pending
- 2019-10-01 JP JP2021542080A patent/JP2022508519A/ja active Pending
- 2019-10-01 WO PCT/US2019/054042 patent/WO2020072478A1/en not_active Ceased
- 2019-10-01 EP EP19868411.0A patent/EP3860768B1/en active Active
- 2019-10-01 CA CA3113981A patent/CA3113981A1/en active Pending
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2021
- 2021-03-31 IL IL281937A patent/IL281937A/en unknown
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2025
- 2025-04-22 US US19/185,906 patent/US20250249191A1/en active Pending
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|---|---|
| CN112996605A (zh) | 2021-06-18 |
| WO2020072478A1 (en) | 2020-04-09 |
| EP3860768A4 (en) | 2022-06-29 |
| US20250249191A1 (en) | 2025-08-07 |
| EP3860768B1 (en) | 2024-05-22 |
| AU2019352957A1 (en) | 2021-04-29 |
| CA3113981A1 (en) | 2020-04-09 |
| US20220001122A1 (en) | 2022-01-06 |
| EP3860768A1 (en) | 2021-08-11 |
| EP3860768C0 (en) | 2024-05-22 |
| JP2022508519A (ja) | 2022-01-19 |
| EP4397343A2 (en) | 2024-07-10 |
| EP4397343A3 (en) | 2024-09-04 |
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