IL276010A - שיטות לניקוי קנבינואידים על ידי שימוש בכרומטוגרפית נוזל:נוזל - Google Patents

שיטות לניקוי קנבינואידים על ידי שימוש בכרומטוגרפית נוזל:נוזל

Info

Publication number
IL276010A
IL276010A IL276010A IL27601020A IL276010A IL 276010 A IL276010 A IL 276010A IL 276010 A IL276010 A IL 276010A IL 27601020 A IL27601020 A IL 27601020A IL 276010 A IL276010 A IL 276010A
Authority
IL
Israel
Prior art keywords
liquid
methods
purifying cannabinoids
liquid chromatography
chromatography
Prior art date
Application number
IL276010A
Other languages
English (en)
Other versions
IL276010B1 (he
IL276010B2 (he
Inventor
Roura Xavier Nadal
Original Assignee
Phytoplant Res S L
Roura Xavier Nadal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=65276144&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL276010(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US15/882,516 external-priority patent/US10207198B2/en
Application filed by Phytoplant Res S L, Roura Xavier Nadal filed Critical Phytoplant Res S L
Publication of IL276010A publication Critical patent/IL276010A/he
Publication of IL276010B1 publication Critical patent/IL276010B1/he
Publication of IL276010B2 publication Critical patent/IL276010B2/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/004—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by obtaining phenols from plant material or from animal material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0203—Solvent extraction of solids with a supercritical fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0288—Applications, solvents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0492—Applications, solvents used
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds or centrifugal chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0004—Crystallisation cooling by heat exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
    • C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/48—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
IL276010A 2018-01-29 2019-01-29 שיטות לניקוי קנבינואידים על ידי שימוש בכרומטוגרפית נוזל:נוזל IL276010B2 (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/882,516 US10207198B2 (en) 2015-01-22 2018-01-29 Methods of purifying cannabinoids using liquid:liquid chromatography
PCT/EP2019/052069 WO2019145552A1 (en) 2018-01-29 2019-01-29 Methods of purifying cannabinoids using liquid:liquid chromatography

Publications (3)

Publication Number Publication Date
IL276010A true IL276010A (he) 2020-08-31
IL276010B1 IL276010B1 (he) 2025-09-01
IL276010B2 IL276010B2 (he) 2026-01-01

Family

ID=65276144

Family Applications (1)

Application Number Title Priority Date Filing Date
IL276010A IL276010B2 (he) 2018-01-29 2019-01-29 שיטות לניקוי קנבינואידים על ידי שימוש בכרומטוגרפית נוזל:נוזל

Country Status (9)

Country Link
EP (1) EP3746419A1 (he)
CN (1) CN111788171A (he)
AU (1) AU2019211188A1 (he)
CA (1) CA3089490A1 (he)
CL (1) CL2020001964A1 (he)
CO (1) CO2020009747A2 (he)
IL (1) IL276010B2 (he)
MX (1) MX2020007960A (he)
WO (1) WO2019145552A1 (he)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020252369A1 (en) * 2019-06-14 2020-12-17 Purisys Llc Crystalline cannabigerol
CN110590511B (zh) * 2019-09-11 2021-05-28 上海同田生物技术股份有限公司 一种同时分离次大麻二酚和大麻萜酚的方法
CN112279752B (zh) * 2020-10-30 2022-11-11 云南芙雅生物科技有限公司 用于工业大麻的大麻素二氧化碳超临界提取方法
CN113135885A (zh) * 2021-04-07 2021-07-20 上海同田生物技术有限公司 一种高速逆流色谱分离纯化四氢次大麻酚的方法
EP4422769A2 (en) 2021-10-26 2024-09-04 Ecofibre USA Inc. Systems and methods for producing hemp extracts and compositions
KR20240116462A (ko) 2021-10-26 2024-07-29 더 유니버시티 오브 뉴캐슬 대마 추출물로 난소암을 치료하는 방법
US12599617B2 (en) 2021-10-26 2026-04-14 Dove Innovation Pty Limited Methods of treating head and neck cancers with hemp extract
IL312245A (he) 2021-10-26 2024-06-01 Ecofibre Usa Inc שיטות לטיפול באנדומטריוזיס והפרעות גינקולוגיות אחרות שאינן סרטניות עם תמצית קנבוס
CN115385780B (zh) * 2022-08-26 2024-02-27 晨光生物科技集团股份有限公司 一种次大麻二酚结晶多晶型物及其制备方法和应用
IL320517A (he) 2022-10-26 2025-06-01 Ecofibre Usa Inc שיטות לטיפול במחלות רגישות לאסטרוגן עם תמצית קנאביס
US12011451B2 (en) 2022-10-26 2024-06-18 Ecofibre USA Inc. Stabilized compositions comprising cannabidiol
FR3146813A1 (fr) * 2023-03-24 2024-09-27 Gilson Purification Procédés de séparation et de purification d'un composé organique contenu dans une matière d'origine naturelle
FR3159605A1 (fr) * 2024-02-26 2025-08-29 Delled Utilisation de lipide biosourcé dans un système biphasique de Chromatographie de Partage Centrifuge
CN120241837A (zh) * 2025-01-10 2025-07-04 中南大学 包含大麻素的药用组合物、制剂及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
GB9518953D0 (en) 1995-09-15 1995-11-15 Pfizer Ltd Pharmaceutical formulations
WO2000035298A1 (en) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Chewing gum containing medicament active agents
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
DE60321318D1 (de) * 2002-02-01 2008-07-10 Resolution Chemicals Ltd Gewinnung von delta-9 tetrahydrocannabinol
US20080103193A1 (en) * 2006-10-26 2008-05-01 Trevor Percival Castor Methods for making compositions and compositions for treating pain and cachexia
US10155708B2 (en) * 2015-01-22 2018-12-18 Phytoplant Research S.L. Methods of purifying cannabinoids, compositions and kits thereof
US9765000B2 (en) 2015-01-22 2017-09-19 Phytoplant Research S.L. Methods of purifying cannabinoids, compositions and kits thereof
EP3061510A1 (de) * 2015-02-27 2016-08-31 Bionorica Ethics GmbH CPC Verteilungschromatographie von Cannabinoiden
BG112018A (bg) * 2015-05-22 2016-11-30 "Побелч-Гле" Оод Метод за получаване на канабиноиден извлек от коноп

Also Published As

Publication number Publication date
EP3746419A1 (en) 2020-12-09
IL276010B1 (he) 2025-09-01
MX2020007960A (es) 2020-09-24
AU2019211188A1 (en) 2020-07-30
CA3089490A1 (en) 2019-08-01
CO2020009747A2 (es) 2020-08-21
WO2019145552A1 (en) 2019-08-01
CN111788171A (zh) 2020-10-16
CL2020001964A1 (es) 2020-12-18
IL276010B2 (he) 2026-01-01

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