IL274138B1 - Flavoured vaporisable formulation - Google Patents
Flavoured vaporisable formulationInfo
- Publication number
- IL274138B1 IL274138B1 IL274138A IL27413820A IL274138B1 IL 274138 B1 IL274138 B1 IL 274138B1 IL 274138 A IL274138 A IL 274138A IL 27413820 A IL27413820 A IL 27413820A IL 274138 B1 IL274138 B1 IL 274138B1
- Authority
- IL
- Israel
- Prior art keywords
- vaporisable formulation
- flavoured vaporisable
- flavoured
- cyclodextrins
- formulation
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 70
- 238000009472 formulation Methods 0.000 title claims 62
- 229920000858 Cyclodextrin Polymers 0.000 claims 18
- 229940097362 cyclodextrins Drugs 0.000 claims 14
- 239000000796 flavoring agent Substances 0.000 claims 13
- 235000019634 flavors Nutrition 0.000 claims 13
- 239000002904 solvent Substances 0.000 claims 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 8
- 238000000034 method Methods 0.000 claims 5
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 3
- 229960002715 nicotine Drugs 0.000 claims 3
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims 2
- 229920001450 Alpha-Cyclodextrin Polymers 0.000 claims 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229940041616 menthol Drugs 0.000 claims 2
- PHXATPHONSXBIL-UHFFFAOYSA-N xi-gamma-Undecalactone Chemical compound CCCCCCCC1CCC(=O)O1 PHXATPHONSXBIL-UHFFFAOYSA-N 0.000 claims 2
- NFLGAXVYCFJBMK-RKDXNWHRSA-N (+)-isomenthone Natural products CC(C)[C@H]1CC[C@@H](C)CC1=O NFLGAXVYCFJBMK-RKDXNWHRSA-N 0.000 claims 1
- RADIRXJQODWKGQ-HWKANZROSA-N 2-Ethoxy-5-(1-propenyl)phenol Chemical compound CCOC1=CC=C(\C=C\C)C=C1O RADIRXJQODWKGQ-HWKANZROSA-N 0.000 claims 1
- NFLGAXVYCFJBMK-UHFFFAOYSA-N Menthone Chemical compound CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 claims 1
- PHXATPHONSXBIL-JTQLQIEISA-N gamma-Undecalactone Natural products CCCCCCC[C@H]1CCC(=O)O1 PHXATPHONSXBIL-JTQLQIEISA-N 0.000 claims 1
- 229940020436 gamma-undecalactone Drugs 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 229930007503 menthone Natural products 0.000 claims 1
- ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 claims 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 claims 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 claims 1
- 235000012141 vanillin Nutrition 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/243—Nicotine
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/34—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a carbocyclic ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/36—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring
- A24B15/40—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms
- A24B15/403—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms having only oxygen as hetero atoms
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/10—Devices using liquid inhalable precursors
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Preparation (AREA)
- Seasonings (AREA)
- Fats And Perfumes (AREA)
- Cosmetics (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
- Detergent Compositions (AREA)
- Manufacture Of Tobacco Products (AREA)
Claims (29)
1. A flavoured vaporisable formulation comprising(i) one or more solvents;(ii) a flavour; and(iii) one or more cyclodextrins;wherein the flavoured vaporisable formulation contains water in an amount of from 0 to wt.% based on the vaporisable formulation;wherein the flavoured vaporisable formulation further comprises nicotine.
2. A flavoured vaporisable formulation according to claim 1 wherein the total content of cyclodextrins is at least 1wt.% based on the vaporisable formulation.
3. A flavoured vaporisable formulation according to claim 1 or 2 wherein the one or more cyclodextrins are selected from the group consisting of substituted or unsubstituted (α)-cyclodextrin, substituted or unsubstituted (β)-cyclodextrin, substituted or unsubstituted (γ)-cyclodextrin, and mixtures thereof.
4. A flavoured vaporisable formulation according to any one of claims 1 to 3 wherein the one or more cyclodextrins comprises at least one or more substituted cyclodextrins.
5. A flavoured vaporisable formulation according to any one of claims 1 to 4 wherein the solvent is selected from water, glycerol, propylene glycol and mixtures thereof.
6. A flavoured vaporisable formulation according to any one of claims 1 to 5 wherein the solvent is at least glycerol, propylene glycol or a mixture thereof.
7. A flavoured vaporisable formulation according to any one of claims 1 to 6 wherein the solvent is mixture of glycerol and propylene glycol.
8. A flavoured vaporisable formulation according to any one of claims 1 to 7 wherein the flavoured vaporisable formulation contains water in an amount of from 0 to 5 wt.% based on the vaporisable formulation.
9. A flavoured vaporisable formulation according to any one of claims 1 to 8 wherein the flavoured vaporisable formulation contains water in an amount of from 0 to 1 wt.% based on the vaporisable formulation. 274138/2
10. A flavoured vaporisable formulation according to any one of claims 1 to 9 wherein the flavoured vaporisable formulation contains water in an amount of from 0 to 0.1 wt.% based on the vaporisable formulation.
11.A flavoured vaporisable formulation according to any one of claims 1 to 10 wherein the solvent is present in an amount of at least 75 wt.% based on the flavoured vaporisable formulation.
12. A flavoured vaporisable formulation according to any one of claims 1 to 11 wherein the solvent is present in an amount of at least 90 wt.% based on the flavoured vaporisable formulation.
13. A flavoured vaporisable formulation according to any one of claims 1 to 12 wherein the one or more flavours are selected from the group consisting of (4-(para- )methoxyphenyl)-2-butanone, vanillin, γ-undecalactone, menthone, 5-propenyl guaethol, menthol, para-mentha-8-thiol-3-one and mixtures thereof.
14. A flavoured vaporisable formulation according to any one of claims 1 to 13 wherein the flavour is at least menthol.
15.A flavoured vaporisable formulation according to any one of claims 1 to 14 wherein the one or more flavours are present in a total amount of no greater than 2wt.% based on the flavoured vaporisable formulation.
16. A flavoured vaporisable formulation according to any one of claims 1 to 15 wherein the one or more flavours are present in a total amount of from 0.01 to 1wt.% based on the flavoured vaporisable formulation.
17. A flavoured vaporisable formulation according to any one of claims 1 to 16 wherein the one or more cyclodextrins are selected from the group consisting of substituted (α)- cyclodextrin, substituted (β)-cyclodextrin, substituted (γ)-cyclodextrin, and mixtures thereof.
18. A flavoured vaporisable formulation according to any one of claims 1 to 17 wherein the one or more cyclodextrins is at least 2‐hydroxy‐propyl‐β‐cyclodextrin.
19. A flavoured vaporisable formulation according to any one of claims 1 to 18 wherein 274138/2 the one or more cyclodextrins are present in a total amount of at least 7wt.% based on the flavoured vaporisable formulation.
20. A flavoured vaporisable formulation according to any one of claims 1 to 19 wherein the one or more cyclodextrins are present in a total amount of no greater than 10wt.% based on the flavoured vaporisable formulation.
21. A flavoured vaporisable formulation according to any one of claims 1 to 20 wherein the one or more cyclodextrins are present in a total amount of from 2 to 9 wt.% based on the flavoured vaporisable formulation.
22. A process for forming a vapour, the process comprising(a) providing a flavoured vaporisable formulation as defined in any one of claims 1 to 21; and (b) vaporising the flavoured vaporisable formulation.
23. A contained flavoured vaporisable formulation comprising(a) a container; and(b) a flavoured vaporisable formulation as defined in any one of claims 1 to 21.
24. An electronic vapour provision system comprising:(a) a vaporiser for vaporising liquid for inhalation by a user of the electronic vapour provision system;(b) a power supply comprising a cell or battery for supplying power to the vaporiser; and(c) a flavoured vaporisable formulation comprising(i) one or more solvents;(ii) a flavour; and(iii) one or more cyclodextrins;wherein the flavoured vaporisable formulation contains water in an amount of from to 10 wt.% based on the vaporisable formulation.
25. An electronic vapour provision system according to claim 24 wherein the flavoured vaporisable formulation is a flavoured vaporisable formulation as defined in any one of claims 2 to 21.
26. A process for at least one of increasing solubility of a flavour and/or reducing loss of flavour over time of a flavoured vaporisable formulationthe process comprising the steps of 274138/2 (a) providing a vaporisable material comprising at least one or more solvents;(b) incorporating into the vaporisable material a flavour and one or more cyclodextrins to form the flavoured vaporisable formulation;wherein the flavoured vaporisable formulation comprises(i) one or more solvents;(ii) a flavour; and(iii) one or more cyclodextrins;wherein the flavoured vaporisable formulation contains water in an amount of from to 10 wt.% based on the vaporisable formulation;wherein the flavoured vaporisable formulation further comprises nicotine.
27. A process according to claim 26 wherein the flavoured vaporisable formulation is a flavoured vaporisable formulation as defined in any one of claims 2 to 21.
28. The flavoured vaporisable composition according to any one of claims 1 - 21 for use in increasing solubility of a flavour and/or reducing loss of flavour over time during storage from the flavoured vaporisable formulation, wherein the flavoured vaporisable formulation comprises(i) one or more solvents;(ii) a flavour; and(iii) one or more cyclodextrins;wherein the flavoured vaporisable formulation contains water in an amount of from 0 to wt.% based on the vaporisable formulation;wherein the flavoured vaporisable formulation further comprises nicotine.
29. The flavoured vaporisable composition for use of claim 28 wherein the flavoured vaporisable formulation is a flavoured vaporisable formulation as defined in any one of claims 2 to 21.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1718033.2A GB201718033D0 (en) | 2017-11-01 | 2017-11-01 | Flavoured vaporisable formulation |
| PCT/GB2018/053137 WO2019086857A1 (en) | 2017-11-01 | 2018-10-31 | Flavoured vaporisable formulation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL274138A IL274138A (en) | 2020-06-30 |
| IL274138B1 true IL274138B1 (en) | 2023-07-01 |
| IL274138B2 IL274138B2 (en) | 2023-11-01 |
Family
ID=60580335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL274138A IL274138B2 (en) | 2017-11-01 | 2018-10-31 | Flavoured vaporisable formulation |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20200345059A1 (en) |
| JP (1) | JP7041261B2 (en) |
| KR (1) | KR102444095B1 (en) |
| CN (1) | CN111629607B (en) |
| AU (1) | AU2018361650B2 (en) |
| BR (1) | BR112020008773A2 (en) |
| CA (1) | CA3080684C (en) |
| GB (1) | GB201718033D0 (en) |
| IL (1) | IL274138B2 (en) |
| MX (1) | MX2020004422A (en) |
| NZ (1) | NZ763603A (en) |
| RU (1) | RU2745353C1 (en) |
| UA (1) | UA125832C2 (en) |
| WO (1) | WO2019086857A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201817862D0 (en) * | 2018-11-01 | 2018-12-19 | Nicoventures Trading Ltd | Aerosolisable formulation |
| GB201917477D0 (en) * | 2019-11-29 | 2020-01-15 | Nicoventures Trading Ltd | Aerosol generation |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5144964A (en) * | 1991-03-14 | 1992-09-08 | Philip Morris Incorporated | Smoking compositions containing a flavorant-release additive |
| CN1044436C (en) * | 1994-01-26 | 1999-08-04 | 日本烟业产业株式会社 | Flavor article |
| CN1124126C (en) * | 1995-08-29 | 2003-10-15 | 威·曼父子有限公司 | Refreshing compositions |
| US6893647B1 (en) * | 2000-05-05 | 2005-05-17 | The Procter & Gamble Company | Cosmetic compositions |
| US20050172976A1 (en) * | 2002-10-31 | 2005-08-11 | Newman Deborah J. | Electrically heated cigarette including controlled-release flavoring |
| CN100381083C (en) * | 2003-04-29 | 2008-04-16 | 韩力 | Electronic nonflammable spraying cigarette |
| US20060105045A1 (en) * | 2004-11-08 | 2006-05-18 | Buchanan Charles M | Cyclodextrin solubilizers for liquid and semi-solid formulations |
| US20070267033A1 (en) * | 2006-02-09 | 2007-11-22 | Philip Morris Usa Inc. | Gamma cyclodextrin flavoring-release additives |
| GB0700889D0 (en) * | 2007-01-17 | 2007-02-21 | British American Tobacco Co | Tobacco, tobacco derivative and/or tobacco substitute products, preparation and uses thereof |
| US20080215023A1 (en) * | 2007-03-01 | 2008-09-04 | Timothy Alan Scavone | Compositions and/or articles comprising cyclodextrin complexing material |
| KR101537922B1 (en) * | 2010-08-20 | 2015-07-17 | 니뽄 다바코 산교 가부시키가이샤 | Tobacco-flavor-releasing material and non-heating type tobacco flavor aspirator comprising same |
| KR20140126350A (en) * | 2012-03-07 | 2014-10-30 | 니뽄 다바코 산교 가부시키가이샤 | Fragrance composition for reducing lingering tobacco odor, and cigarette |
| CN102813278B (en) * | 2012-08-09 | 2017-03-15 | 深圳瀚星翔科技有限公司 | A kind of mixed type electronic cigarette tobacco liquid |
| CN102960852B (en) * | 2012-11-14 | 2015-04-22 | 湖北中烟工业有限责任公司 | Light-fragrance electronic cigarette atomized smoke solution and preparation method thereof |
| GB2528673B (en) * | 2014-07-25 | 2020-07-01 | Nicoventures Holdings Ltd | Aerosol provision system |
| CN104544540B (en) * | 2014-12-24 | 2016-05-04 | 广西中烟工业有限责任公司 | A kind of preparation method of vacuum freeze drying fruit grain electronics tobacco tar |
| US20160198759A1 (en) * | 2015-01-13 | 2016-07-14 | Zip Llc | E-cigarette or vaping fluid |
| CN104770863B (en) * | 2015-02-11 | 2020-05-22 | 贵州中烟工业有限责任公司 | Electronic cigarette liquid with herbal tea flavor and application thereof |
| CN105029681B (en) * | 2015-07-14 | 2017-10-31 | 中国烟草总公司郑州烟草研究院 | Natural perfume material refined liquid, tobacco juice suitable for tobacco juice for electronic smoke and preparation method thereof |
| CN105581378B (en) * | 2016-03-17 | 2018-05-18 | 云南中烟工业有限责任公司 | A kind of self generating gas ultrasonic atomizatio electronics flue gas Transmission system |
| CN106520369A (en) * | 2016-11-18 | 2017-03-22 | 湖北中烟工业有限责任公司 | Essence for cigarette lap adhesive and use method thereof |
-
2017
- 2017-11-01 GB GBGB1718033.2A patent/GB201718033D0/en not_active Ceased
-
2018
- 2018-10-31 CA CA3080684A patent/CA3080684C/en active Active
- 2018-10-31 IL IL274138A patent/IL274138B2/en unknown
- 2018-10-31 CN CN201880070956.5A patent/CN111629607B/en active Active
- 2018-10-31 WO PCT/GB2018/053137 patent/WO2019086857A1/en active Search and Examination
- 2018-10-31 KR KR1020207012384A patent/KR102444095B1/en active IP Right Grant
- 2018-10-31 AU AU2018361650A patent/AU2018361650B2/en active Active
- 2018-10-31 JP JP2020523274A patent/JP7041261B2/en active Active
- 2018-10-31 BR BR112020008773-4A patent/BR112020008773A2/en unknown
- 2018-10-31 UA UAA202002570A patent/UA125832C2/en unknown
- 2018-10-31 NZ NZ763603A patent/NZ763603A/en unknown
- 2018-10-31 US US16/761,028 patent/US20200345059A1/en active Pending
- 2018-10-31 MX MX2020004422A patent/MX2020004422A/en unknown
- 2018-10-31 RU RU2020114475A patent/RU2745353C1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| GB201718033D0 (en) | 2017-12-13 |
| AU2018361650B2 (en) | 2021-02-11 |
| AU2018361650A1 (en) | 2020-05-07 |
| WO2019086857A1 (en) | 2019-05-09 |
| BR112020008773A2 (en) | 2020-10-20 |
| NZ763603A (en) | 2023-07-28 |
| IL274138B2 (en) | 2023-11-01 |
| JP7041261B2 (en) | 2022-03-23 |
| CA3080684A1 (en) | 2019-05-09 |
| US20200345059A1 (en) | 2020-11-05 |
| JP2021500890A (en) | 2021-01-14 |
| KR20200060478A (en) | 2020-05-29 |
| CN111629607A (en) | 2020-09-04 |
| CA3080684C (en) | 2022-07-12 |
| RU2745353C1 (en) | 2021-03-24 |
| CN111629607B (en) | 2022-10-28 |
| IL274138A (en) | 2020-06-30 |
| MX2020004422A (en) | 2020-07-29 |
| UA125832C2 (en) | 2022-06-15 |
| KR102444095B1 (en) | 2022-09-15 |
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