IL270984B1 - Methods and preparations for treating congenital diarrheal disorder - Google Patents
Methods and preparations for treating congenital diarrheal disorderInfo
- Publication number
- IL270984B1 IL270984B1 IL270984A IL27098419A IL270984B1 IL 270984 B1 IL270984 B1 IL 270984B1 IL 270984 A IL270984 A IL 270984A IL 27098419 A IL27098419 A IL 27098419A IL 270984 B1 IL270984 B1 IL 270984B1
- Authority
- IL
- Israel
- Prior art keywords
- composition
- crofelemer
- per day
- subject
- administering
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762513251P | 2017-05-31 | 2017-05-31 | |
| PCT/US2018/035468 WO2018222919A1 (en) | 2017-05-31 | 2018-05-31 | Methods and compositions for treating congenital diarrhea disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL270984A IL270984A (en) | 2020-01-30 |
| IL270984B1 true IL270984B1 (en) | 2026-01-01 |
Family
ID=64455032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL270984A IL270984B1 (en) | 2017-05-31 | 2019-11-27 | Methods and preparations for treating congenital diarrheal disorder |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11857510B2 (https=) |
| EP (1) | EP3634581B8 (https=) |
| JP (1) | JP2020525407A (https=) |
| CN (1) | CN110831667A (https=) |
| AU (1) | AU2018278312B2 (https=) |
| CA (1) | CA3065797A1 (https=) |
| DK (1) | DK3634581T3 (https=) |
| ES (1) | ES2988850T3 (https=) |
| FI (1) | FI3634581T3 (https=) |
| IL (1) | IL270984B1 (https=) |
| JO (1) | JOP20190275B1 (https=) |
| WO (1) | WO2018222919A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20190276B1 (ar) | 2017-05-31 | 2024-04-18 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج إسهال الحمض الصفراوي، والإسهال المرتبط باستئصال الأمعاء الدقيقة أو إزالة المرارة، ومتلازمة الأمعاء القصيرة |
| JOP20190275B1 (ar) | 2017-05-31 | 2024-12-22 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج اضطراب إسهال خِلقي |
| MX2022016367A (es) * | 2020-06-19 | 2023-01-30 | Napo Pharmaceuticals Inc | Metodos y composiciones para el tratamiento de la diarrea inducida por quimioterapia. |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011044167A1 (en) * | 2009-10-06 | 2011-04-14 | University Of California, San Francisco | Methods of treating diseases with proanthocyanidin oligomers such as crofelemer |
| US20140011869A1 (en) * | 1996-10-16 | 2014-01-09 | Edward James Rozhon | Compositions and methods of treatment with proanthocyanidin polymer antidiarrheal compositions |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0214317B1 (fr) | 1985-08-30 | 1988-08-17 | Societe Des Produits Nestle S.A. | Produit diététique à activité dépurative et anti-diarrhéique et son procédé de préparation |
| US5211944A (en) | 1990-10-12 | 1993-05-18 | Shaman Pharmaceuticals, Inc. | Proanthocyanidin polymers having antiviral activity and methods of obtaining same |
| SI9011933A (sl) | 1990-10-15 | 1998-06-30 | TANIN SEVNICA Kemična industrija p.o. | Kostanjev taninski ekstrakt, postopek za njegovo pridobivanje in njegova uporaba |
| US7767203B2 (en) | 1998-08-07 | 2010-08-03 | Ganeden Biotech, Inc. | Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption |
| WO2000047062A2 (en) | 1999-02-01 | 2000-08-17 | Shaman Pharmaceuticals, Inc. | Enteric formulations of proanthocyanidin polymer dietary supplements and methods for preparing same |
| US7235573B2 (en) | 2002-09-30 | 2007-06-26 | The Regents Of The University Of California | Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors |
| CA2657803C (en) | 2006-05-01 | 2019-01-08 | Napo Pharmaceuticals, Inc. | Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer |
| US20070254050A1 (en) | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
| SG195538A1 (en) | 2006-05-01 | 2013-12-30 | Napo Pharmaceuticals Inc | Method for treatment of constipation-predominant irritable bowel syndrome |
| EP2632550B1 (en) | 2010-10-31 | 2017-05-03 | Napo Pharmaceuticals, Inc. | Methods and compositions for treating hiv-associated diarrhea |
| EP3393460A4 (en) | 2015-12-23 | 2019-09-25 | Vanessa Research, Inc. | COMPOSITIONS AND METHODS FOR TREATING MVID AND RELATED DISEASES |
| US11389424B2 (en) | 2017-03-09 | 2022-07-19 | Napo Pharmaceuticals, Inc. | Methods and compositions for treating chemotherapy-induced diarrhea |
| JOP20190275B1 (ar) | 2017-05-31 | 2024-12-22 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج اضطراب إسهال خِلقي |
| JOP20190276B1 (ar) | 2017-05-31 | 2024-04-18 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج إسهال الحمض الصفراوي، والإسهال المرتبط باستئصال الأمعاء الدقيقة أو إزالة المرارة، ومتلازمة الأمعاء القصيرة |
-
2018
- 2018-05-31 JO JOJO/P/2019/0275A patent/JOP20190275B1/ar active
- 2018-05-31 DK DK18810153.9T patent/DK3634581T3/da active
- 2018-05-31 JP JP2019566125A patent/JP2020525407A/ja active Pending
- 2018-05-31 EP EP18810153.9A patent/EP3634581B8/en active Active
- 2018-05-31 FI FIEP18810153.9T patent/FI3634581T3/fi active
- 2018-05-31 CN CN201880043974.4A patent/CN110831667A/zh active Pending
- 2018-05-31 ES ES18810153T patent/ES2988850T3/es active Active
- 2018-05-31 AU AU2018278312A patent/AU2018278312B2/en active Active
- 2018-05-31 US US16/617,463 patent/US11857510B2/en active Active
- 2018-05-31 CA CA3065797A patent/CA3065797A1/en active Pending
- 2018-05-31 WO PCT/US2018/035468 patent/WO2018222919A1/en not_active Ceased
-
2019
- 2019-11-27 IL IL270984A patent/IL270984B1/en unknown
-
2023
- 2023-11-27 US US18/520,464 patent/US20240325346A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140011869A1 (en) * | 1996-10-16 | 2014-01-09 | Edward James Rozhon | Compositions and methods of treatment with proanthocyanidin polymer antidiarrheal compositions |
| WO2011044167A1 (en) * | 2009-10-06 | 2011-04-14 | University Of California, San Francisco | Methods of treating diseases with proanthocyanidin oligomers such as crofelemer |
Also Published As
| Publication number | Publication date |
|---|---|
| FI3634581T3 (fi) | 2024-08-16 |
| CA3065797A1 (en) | 2018-12-06 |
| EP3634581B8 (en) | 2024-09-11 |
| JP2020525407A (ja) | 2020-08-27 |
| WO2018222919A1 (en) | 2018-12-06 |
| US20240325346A1 (en) | 2024-10-03 |
| EP3634581A1 (en) | 2020-04-15 |
| US20200108047A1 (en) | 2020-04-09 |
| ES2988850T3 (es) | 2024-11-21 |
| DK3634581T3 (da) | 2024-08-26 |
| JOP20190275B1 (ar) | 2024-12-22 |
| AU2018278312A1 (en) | 2020-01-02 |
| IL270984A (en) | 2020-01-30 |
| US11857510B2 (en) | 2024-01-02 |
| AU2018278312B2 (en) | 2024-07-04 |
| EP3634581A4 (en) | 2021-02-24 |
| EP3634581B1 (en) | 2024-07-31 |
| CN110831667A (zh) | 2020-02-21 |
| JOP20190275A1 (ar) | 2019-11-27 |
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