IL268220B - Co-crystals of substituted glycine compounds and their uses - Google Patents
Co-crystals of substituted glycine compounds and their usesInfo
- Publication number
- IL268220B IL268220B IL268220A IL26822019A IL268220B IL 268220 B IL268220 B IL 268220B IL 268220 A IL268220 A IL 268220A IL 26822019 A IL26822019 A IL 26822019A IL 268220 B IL268220 B IL 268220B
- Authority
- IL
- Israel
- Prior art keywords
- crystals
- substituted glycine
- glycine compounds
- compounds
- substituted
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title 1
- 125000003630 glycyl group Chemical class [H]N([H])C([H])([H])C(*)=O 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/15—Fumaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/255—Tartaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/430,750 US9877942B1 (en) | 2017-02-13 | 2017-02-13 | Co-crystals of substituted glycine and uses thereof |
| PCT/CN2018/072186 WO2018145553A1 (en) | 2017-02-13 | 2018-01-11 | Co-crystals of substituted glycine compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL268220A IL268220A (en) | 2019-09-26 |
| IL268220B true IL268220B (en) | 2022-04-01 |
Family
ID=61005084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL268220A IL268220B (en) | 2017-02-13 | 2019-07-22 | Co-crystals of substituted glycine compounds and their uses |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US9877942B1 (enExample) |
| EP (1) | EP3579828B1 (enExample) |
| JP (2) | JP2020507567A (enExample) |
| KR (1) | KR20190118574A (enExample) |
| CN (1) | CN110520117A (enExample) |
| CA (1) | CA3051284A1 (enExample) |
| IL (1) | IL268220B (enExample) |
| MX (1) | MX393880B (enExample) |
| RU (1) | RU2019128576A (enExample) |
| TW (1) | TWI670058B (enExample) |
| WO (1) | WO2018145553A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2936094T3 (es) | 2016-06-13 | 2023-03-14 | Syneurx Int Taiwan Corp | Cocristales de benzoato de sodio y usos de los mismos |
| US9877942B1 (en) | 2017-02-13 | 2018-01-30 | Syneurx International (Taiwan) Corp. | Co-crystals of substituted glycine and uses thereof |
| CN113233976B (zh) * | 2021-05-08 | 2021-11-16 | 广州萃普生物科技有限公司 | 一种没食子酸和氨基乙酸共晶及含有该共晶的美白膏霜 |
| EP4419499A1 (en) | 2021-10-20 | 2024-08-28 | Purac Biochem B.V. | Co-crystal of citric acid and glycine and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1073432E (pt) * | 1998-04-14 | 2007-10-22 | Gen Hospital Corp | Utilização da d-alanina ou da d-serina para o tratamento da esquizofrenia |
| EP1727520A2 (en) * | 2003-12-09 | 2006-12-06 | Medcrystalforms, Llc | Method of preparation of mixed phase co-crystals with active agents |
| US20100204204A1 (en) * | 2007-06-06 | 2010-08-12 | University Of South Florida | Nutraceutical co-crystal compositions |
| WO2009018368A1 (en) * | 2007-07-30 | 2009-02-05 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Combination treatment of nmda (n-methyl-d-aspartate)-enhancer, glycine transporter inhibitor, d-amino acid oxidase inhibitor (daaoi) for neuropsychiatric disorders |
| GB201411802D0 (en) * | 2014-07-02 | 2014-08-13 | Univ Bradford | Effervescent compositions |
| US9877942B1 (en) | 2017-02-13 | 2018-01-30 | Syneurx International (Taiwan) Corp. | Co-crystals of substituted glycine and uses thereof |
-
2017
- 2017-02-13 US US15/430,750 patent/US9877942B1/en active Active
-
2018
- 2018-01-09 US US15/866,303 patent/US10328041B2/en active Active
- 2018-01-11 WO PCT/CN2018/072186 patent/WO2018145553A1/en not_active Ceased
- 2018-01-11 RU RU2019128576A patent/RU2019128576A/ru unknown
- 2018-01-11 CN CN201880011387.7A patent/CN110520117A/zh active Pending
- 2018-01-11 TW TW107101039A patent/TWI670058B/zh active
- 2018-01-11 CA CA3051284A patent/CA3051284A1/en active Pending
- 2018-01-11 JP JP2019542698A patent/JP2020507567A/ja active Pending
- 2018-01-11 KR KR1020197023303A patent/KR20190118574A/ko not_active Ceased
- 2018-01-11 MX MX2019009616A patent/MX393880B/es unknown
- 2018-01-11 EP EP18751659.6A patent/EP3579828B1/en active Active
- 2018-04-03 US US15/944,722 patent/US10328042B2/en active Active
-
2019
- 2019-05-15 US US16/412,804 patent/US10765651B2/en active Active
- 2019-07-22 IL IL268220A patent/IL268220B/en unknown
-
2023
- 2023-03-29 JP JP2023053835A patent/JP7723991B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| TWI670058B (zh) | 2019-09-01 |
| JP7723991B2 (ja) | 2025-08-15 |
| US20180228753A1 (en) | 2018-08-16 |
| EP3579828B1 (en) | 2025-03-26 |
| US20190262299A1 (en) | 2019-08-29 |
| WO2018145553A1 (en) | 2018-08-16 |
| MX393880B (es) | 2025-03-24 |
| US20180228754A1 (en) | 2018-08-16 |
| JP2020507567A (ja) | 2020-03-12 |
| CA3051284A1 (en) | 2018-08-16 |
| EP3579828A1 (en) | 2019-12-18 |
| EP3579828A4 (en) | 2020-11-18 |
| IL268220A (en) | 2019-09-26 |
| MX2019009616A (es) | 2019-10-14 |
| RU2019128576A (ru) | 2021-03-15 |
| TW201840308A (zh) | 2018-11-16 |
| JP2023082101A (ja) | 2023-06-13 |
| RU2019128576A3 (enExample) | 2021-05-14 |
| CN110520117A (zh) | 2019-11-29 |
| US10765651B2 (en) | 2020-09-08 |
| US10328041B2 (en) | 2019-06-25 |
| US9877942B1 (en) | 2018-01-30 |
| KR20190118574A (ko) | 2019-10-18 |
| US10328042B2 (en) | 2019-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL273236A (en) | Pyrazolopyrimidine compounds and their uses | |
| ZA201904500B (en) | Separate configuration of numerology-associated resources | |
| ZA201905677B (en) | Glycan-interacting compounds and methods of use | |
| GB201708652D0 (en) | Novel compounds and uses | |
| GB201714745D0 (en) | New compounds and uses | |
| IL254655A0 (en) | Ibrutinib co-crystal | |
| GB201501583D0 (en) | Uses of co-crystals | |
| PT3102555T (pt) | Composições de compostos e seus usos | |
| IL263941B (en) | Sustained-release pregabalin dosage forms | |
| EP3664805A4 (en) | POLYMORPHIC AND CO-CRYSTALS OF ROXADUSTAT | |
| GB201714734D0 (en) | New compounds and uses | |
| SI3577125T1 (sl) | Kristalinične oblike tenofovirijevega alafenamida | |
| ITUA20161846A1 (it) | Procedimento ed architettura di regolazione remota di un'audioprotesi | |
| GB201714740D0 (en) | New compounds and uses | |
| PL3651432T3 (pl) | Wybór wersji ip | |
| PL3313865T3 (pl) | Syntetyczne związki peptydowe i sposoby zastosowania | |
| IL274627A (en) | Solid forms of valbenazine | |
| GB201812339D0 (en) | Reconcilliation of run-time and configuration discrepancies | |
| PT3661491T (pt) | 3-metilmetcatinona para uso no tratamento de um indivíduo sob uma intervenção psicoterapêutica | |
| IL268220B (en) | Co-crystals of substituted glycine compounds and their uses | |
| PL3532457T3 (pl) | Postacie krystaliczne hydroksynorketaminy | |
| IL267937A (en) | Amide compounds and their use | |
| IL263673A (en) | Solid state forms of spiro-oxindole compounds | |
| GB201712110D0 (en) | New compounds and uses | |
| SG11202105136WA (en) | Application of chidamide |