IL262390B1 - Semaglutide in cardiovascular conditions - Google Patents

Semaglutide in cardiovascular conditions

Info

Publication number
IL262390B1
IL262390B1 IL262390A IL26239018A IL262390B1 IL 262390 B1 IL262390 B1 IL 262390B1 IL 262390 A IL262390 A IL 262390A IL 26239018 A IL26239018 A IL 26239018A IL 262390 B1 IL262390 B1 IL 262390B1
Authority
IL
Israel
Prior art keywords
semaglutide
pharmaceutical composition
subject
mace
fatal
Prior art date
Application number
IL262390A
Other languages
English (en)
Hebrew (he)
Other versions
IL262390A (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58668875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL262390(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL262390A publication Critical patent/IL262390A/en
Publication of IL262390B1 publication Critical patent/IL262390B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
IL262390A 2016-04-28 2018-10-15 Semaglutide in cardiovascular conditions IL262390B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16167458 2016-04-28
EP16188262 2016-09-12
PCT/EP2017/060160 WO2017186896A1 (en) 2016-04-28 2017-04-28 Semaglutide in cardiovascular conditions

Publications (2)

Publication Number Publication Date
IL262390A IL262390A (en) 2018-12-31
IL262390B1 true IL262390B1 (en) 2023-05-01

Family

ID=58668875

Family Applications (1)

Application Number Title Priority Date Filing Date
IL262390A IL262390B1 (en) 2016-04-28 2018-10-15 Semaglutide in cardiovascular conditions

Country Status (24)

Country Link
US (3) US12569543B2 (https=)
EP (1) EP3448416B1 (https=)
JP (1) JP7221694B2 (https=)
KR (3) KR20180135012A (https=)
CN (1) CN109069589B (https=)
AU (2) AU2017256774B2 (https=)
BR (1) BR112018072020A2 (https=)
CA (1) CA3022535A1 (https=)
CL (1) CL2018003045A1 (https=)
DK (1) DK3448416T3 (https=)
ES (1) ES2928007T3 (https=)
HR (1) HRP20221150T1 (https=)
HU (1) HUE060040T2 (https=)
IL (1) IL262390B1 (https=)
MA (1) MA44762A (https=)
MX (1) MX2018012700A (https=)
MY (1) MY202967A (https=)
PH (1) PH12018502274B1 (https=)
PL (1) PL3448416T3 (https=)
RS (1) RS63630B1 (https=)
RU (1) RU2768283C2 (https=)
SI (1) SI3448416T1 (https=)
WO (1) WO2017186896A1 (https=)
ZA (2) ZA202507394B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7221694B2 (ja) 2016-04-28 2023-02-14 ノヴォ ノルディスク アー／エス 心血管状態におけるセマグルチド
HRP20240485T1 (hr) 2017-08-24 2024-07-05 Novo Nordisk A/S Pripravci glp-1 i njihova upotreba
HRP20230929T1 (hr) * 2018-10-26 2023-11-24 Novo Nordisk A/S Stabilni pripravci semaglutida i njihova upotreba
CN113194929B (zh) * 2018-12-21 2022-12-09 诺和诺德股份有限公司 Glp-1肽的喷雾干燥工艺
PE20230819A1 (es) * 2020-02-18 2023-05-19 Novo Nordisk As Composiciones y usos de glp-1
CN114699510B (zh) * 2021-12-29 2024-07-16 浙江湃肽生物有限公司 一种司美格鲁肽微针阵列及其制备方法
AU2023285400A1 (en) * 2022-06-08 2024-12-05 Zydus Lifesciences Limited Reusable multi-dose, variable dose, single pen injector for type 2 diabetes and weight management
CN117462654A (zh) * 2023-09-28 2024-01-30 武汉大学人民医院（湖北省人民医院） 司美格鲁肽在制备预防或治疗心肌重构的药物中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084563A1 (en) * 2002-04-04 2003-10-16 Novo Nordisk A/S Glp-1 agonist and cardiovascular complications
WO2012107476A1 (en) * 2011-02-09 2012-08-16 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
WO2013037690A1 (en) * 2011-09-06 2013-03-21 Novo Nordisk A/S Glp-1 derivatives
WO2015071355A1 (en) * 2013-11-15 2015-05-21 Novo Nordisk A/S Selective pyy compounds and uses thereof

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AU2002316811A1 (en) * 2001-06-28 2003-03-03 Novo Nordisk A/S Stable formulation of modified glp-1
TR201906789T4 (tr) 2003-11-20 2019-05-21 Novo Nordisk As Üretim ve enjeksiyon cihazlarında kullanım için en uygun olan propilen glikol ihtiva eden peptit formülasyonları.
TWI372629B (en) * 2005-03-18 2012-09-21 Novo Nordisk As Acylated glp-1 compounds
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
JP5662453B2 (ja) 2009-10-02 2015-01-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物の治療上の使用
KR20240090632A (ko) 2009-11-27 2024-06-21 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴과 같은 ｄｐｐ－ｉｖ 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
CA3070513C (en) * 2010-05-05 2023-01-03 Boehringer Ingelheim International Gmbh A dpp-4 inhibitor for use in treatment of skin-alterations or necrosis
KR20130093012A (ko) 2010-06-24 2013-08-21 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
MX377589B (es) * 2010-12-16 2025-03-10 Novo Nordisk As Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico.
US20130172244A1 (en) 2011-12-29 2013-07-04 Thomas Klein Subcutaneous therapeutic use of dpp-4 inhibitor
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
WO2013171166A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis
JP6374862B2 (ja) 2012-05-24 2018-08-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 自己免疫性糖尿病、特に、ｌａｄａの治療に使用するためのｄｐｐ−４阻害剤としてのキサンチン誘導体
US20150290294A1 (en) 2012-11-02 2015-10-15 Mansoor Husain Methods for inhibiting platelet aggregation using glp-1 receptor agonists
WO2014124860A1 (en) 2013-02-14 2014-08-21 Boehringer Ingelheim International Gmbh Specific pde4b-inhibitors for the treatment of diabetes mellitus
EP2968344A1 (en) 2013-03-15 2016-01-20 Boehringer Ingelheim International GmbH Use of linagliptin in cardio- and renoprotective antidiabetic therapy
US8969371B1 (en) 2013-12-06 2015-03-03 Orexigen Therapeutics, Inc. Compositions and methods for weight loss in at risk patient populations
US10894054B2 (en) 2015-04-07 2021-01-19 Intercept Pharmaceuticals, Inc. FXR agonist compositions for combination therapy
US9968659B2 (en) 2016-03-04 2018-05-15 Novo Nordisk A/S Liraglutide in cardiovascular conditions
JP7221694B2 (ja) * 2016-04-28 2023-02-14 ノヴォ ノルディスク アー／エス 心血管状態におけるセマグルチド

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084563A1 (en) * 2002-04-04 2003-10-16 Novo Nordisk A/S Glp-1 agonist and cardiovascular complications
WO2012107476A1 (en) * 2011-02-09 2012-08-16 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
WO2013037690A1 (en) * 2011-09-06 2013-03-21 Novo Nordisk A/S Glp-1 derivatives
WO2015071355A1 (en) * 2013-11-15 2015-05-21 Novo Nordisk A/S Selective pyy compounds and uses thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS, NOVO NORDISK SUCCESSFULLY COMPLETES FIRST PHASE 3A TRIAL WITH SEMAGLUTIDE IN PEOPLE WITH TYPE 2 DIABETES, 10 July 2015 (2015-07-10) *
HALIMI, S., SECURITE CARDIOVASCULAIRE DES INCRETINES ET DES INHIBITEURS DES CO-TRANSPORTEURS SODIUM-GLUCOSE DE TYPE 2 (SGLT2), 1 December 2015 (2015-12-01) *
SCHEEN, ANDRE J., CARDIOVASCULAR SAFETY OF ALBIGLUTIDE AND OTHER GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONISTS., 11 August 2015 (2015-08-11) *
SHEIKH, ASFANDYAR., DIRECT CARDIOVASCULAR EFFECTS OF GLUCAGON LIKE PEPTIDE-1., 29 August 2013 (2013-08-29) *

Also Published As

Publication number Publication date
PL3448416T3 (pl) 2022-11-07
KR102778218B1 (ko) 2025-03-10
US20250288649A1 (en) 2025-09-18
PH12018502274A1 (en) 2019-09-09
IL262390A (en) 2018-12-31
AU2017256774B2 (en) 2024-07-11
KR20250038818A (ko) 2025-03-19
ES2928007T3 (es) 2022-11-14
AU2017256774A1 (en) 2018-11-01
JP2019514925A (ja) 2019-06-06
JP7221694B2 (ja) 2023-02-14
EP3448416B1 (en) 2022-08-10
EP3448416A1 (en) 2019-03-06
HUE060040T2 (hu) 2023-01-28
CA3022535A1 (en) 2017-11-02
RU2018140900A (ru) 2020-05-28
WO2017186896A1 (en) 2017-11-02
ZA202507395B (en) 2025-09-25
HRP20221150T1 (hr) 2022-11-25
AU2024227113A1 (en) 2024-10-31
US20250262281A1 (en) 2025-08-21
RU2768283C2 (ru) 2022-03-23
RS63630B1 (sr) 2022-10-31
US20190134162A1 (en) 2019-05-09
ZA202507394B (en) 2025-09-25
CN109069589B (zh) 2022-09-06
BR112018072020A2 (pt) 2019-02-12
KR20220147712A (ko) 2022-11-03
SI3448416T1 (sl) 2022-10-28
MA44762A (fr) 2019-03-06
US12569543B2 (en) 2026-03-10
PH12018502274B1 (en) 2024-02-28
CL2018003045A1 (es) 2018-12-14
MY202967A (en) 2024-05-31
RU2018140900A3 (https=) 2020-09-28
KR20180135012A (ko) 2018-12-19
CN109069589A (zh) 2018-12-21
MX2018012700A (es) 2019-01-30
DK3448416T3 (da) 2022-10-03

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