IL261179B - פורמולציות של פמטרקסד - Google Patents
פורמולציות של פמטרקסדInfo
- Publication number
- IL261179B IL261179B IL261179A IL26117918A IL261179B IL 261179 B IL261179 B IL 261179B IL 261179 A IL261179 A IL 261179A IL 26117918 A IL26117918 A IL 26117918A IL 261179 B IL261179 B IL 261179B
- Authority
- IL
- Israel
- Prior art keywords
- pemetrexed formulations
- pemetrexed
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2016/018703 WO2017142556A1 (en) | 2016-02-19 | 2016-02-19 | Pemetrexed formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL261179A IL261179A (he) | 2018-10-31 |
| IL261179B true IL261179B (he) | 2022-03-01 |
Family
ID=59625349
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL301291A IL301291A (he) | 2016-02-19 | 2016-02-19 | ניסוחים פמטרקס |
| IL261179A IL261179B (he) | 2016-02-19 | 2018-08-15 | פורמולציות של פמטרקסד |
| IL290647A IL290647B2 (he) | 2016-02-19 | 2022-02-15 | ניסוחים פמטרקס |
| IL312427A IL312427B1 (he) | 2016-02-19 | 2024-04-25 | פורמולציות פמטרקסד |
| IL324306A IL324306A (he) | 2016-02-19 | 2025-10-28 | פורמולציות פמטרקסד |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL301291A IL301291A (he) | 2016-02-19 | 2016-02-19 | ניסוחים פמטרקס |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL290647A IL290647B2 (he) | 2016-02-19 | 2022-02-15 | ניסוחים פמטרקס |
| IL312427A IL312427B1 (he) | 2016-02-19 | 2024-04-25 | פורמולציות פמטרקסד |
| IL324306A IL324306A (he) | 2016-02-19 | 2025-10-28 | פורמולציות פמטרקסד |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP3416646A4 (he) |
| JP (1) | JP2019505561A (he) |
| KR (2) | KR102794126B1 (he) |
| CN (1) | CN109152778B (he) |
| AU (3) | AU2016393213B2 (he) |
| CA (1) | CA3014755C (he) |
| IL (5) | IL301291A (he) |
| MX (2) | MX2022009547A (he) |
| WO (1) | WO2017142556A1 (he) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6686365B2 (en) * | 2000-02-04 | 2004-02-03 | Eli Lilly And Company | Pharmaceutical composition |
| DE602007011384D1 (de) * | 2006-08-14 | 2011-02-03 | Sicor Inc | Verfahren zur herstellung lipophiler pharmazeutisch akzeptabler salze aus pemetrexed-disäure |
| US9655898B2 (en) * | 2010-07-28 | 2017-05-23 | Eagle Pharmaceuticals, Inc. | Pharmaceutical compositions containing pemetrexed having extended storage stability |
| IN2012DE00912A (he) * | 2012-03-27 | 2015-09-11 | Fresenius Kabi Oncology Ltd | |
| EP2666463A1 (en) * | 2012-05-21 | 2013-11-27 | Synthon BV | Stabilized liquid composition comprising pemetrexed |
| EP2854768B2 (en) * | 2012-05-30 | 2025-06-18 | Fresenius Kabi Oncology Limited | Pharmaceutical compositions of pemetrexed |
| WO2013179310A1 (en) * | 2012-05-31 | 2013-12-05 | Mylan Laboratories Limited | Stable aqueous compositions of pemetrexed |
| JP6099557B2 (ja) * | 2013-12-27 | 2017-03-22 | 富士フイルム株式会社 | 注射液製剤及びその製造方法 |
| KR101703980B1 (ko) * | 2013-12-30 | 2017-02-08 | 주식회사 삼양바이오팜 | 항산화제를 함유하지 않는 약학 조성물 및 그의 제조방법 |
| WO2015193517A2 (en) * | 2014-10-16 | 2015-12-23 | Synthon B.V. | Liquid pharmaceutical composition comprising pemetrexed |
-
2016
- 2016-02-19 MX MX2022009547A patent/MX2022009547A/es unknown
- 2016-02-19 KR KR1020247009885A patent/KR102794126B1/ko active Active
- 2016-02-19 EP EP16890851.5A patent/EP3416646A4/en active Pending
- 2016-02-19 JP JP2018544196A patent/JP2019505561A/ja not_active Withdrawn
- 2016-02-19 CA CA3014755A patent/CA3014755C/en active Active
- 2016-02-19 MX MX2018010037A patent/MX2018010037A/es unknown
- 2016-02-19 CN CN201680084554.1A patent/CN109152778B/zh active Active
- 2016-02-19 AU AU2016393213A patent/AU2016393213B2/en active Active
- 2016-02-19 IL IL301291A patent/IL301291A/he unknown
- 2016-02-19 WO PCT/US2016/018703 patent/WO2017142556A1/en not_active Ceased
- 2016-02-19 KR KR1020187027212A patent/KR20180132643A/ko not_active Ceased
-
2018
- 2018-08-15 IL IL261179A patent/IL261179B/he unknown
-
2022
- 2022-02-15 IL IL290647A patent/IL290647B2/he unknown
-
2023
- 2023-04-04 AU AU2023202089A patent/AU2023202089B2/en active Active
-
2024
- 2024-04-25 IL IL312427A patent/IL312427B1/he unknown
-
2025
- 2025-08-29 AU AU2025223868A patent/AU2025223868A1/en active Pending
- 2025-10-28 IL IL324306A patent/IL324306A/he unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN109152778B (zh) | 2021-08-10 |
| IL290647A (he) | 2022-04-01 |
| AU2023202089A1 (en) | 2023-06-01 |
| AU2023202089B2 (en) | 2025-05-29 |
| CA3014755A1 (en) | 2017-08-24 |
| IL301291A (he) | 2023-05-01 |
| AU2016393213B2 (en) | 2022-03-31 |
| IL261179A (he) | 2018-10-31 |
| IL290647B1 (he) | 2023-04-01 |
| WO2017142556A1 (en) | 2017-08-24 |
| MX2022009547A (es) | 2022-09-09 |
| AU2025223868A1 (en) | 2025-09-18 |
| IL312427A (he) | 2024-06-01 |
| KR20240049356A (ko) | 2024-04-16 |
| KR102794126B1 (ko) | 2025-04-11 |
| IL290647B2 (he) | 2023-08-01 |
| IL324306A (he) | 2025-12-01 |
| MX2018010037A (es) | 2019-07-04 |
| CA3014755C (en) | 2023-11-14 |
| EP3416646A4 (en) | 2019-09-04 |
| KR20180132643A (ko) | 2018-12-12 |
| EP3416646A1 (en) | 2018-12-26 |
| IL312427B1 (he) | 2025-12-01 |
| AU2016393213A1 (en) | 2018-10-04 |
| CN109152778A (zh) | 2019-01-04 |
| JP2019505561A (ja) | 2019-02-28 |
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