IL258854B2 - Preparations containing cannabidiol and secondary pharmacological agents for cancer treatment - Google Patents

Preparations containing cannabidiol and secondary pharmacological agents for cancer treatment

Info

Publication number
IL258854B2
IL258854B2 IL258854A IL25885418A IL258854B2 IL 258854 B2 IL258854 B2 IL 258854B2 IL 258854 A IL258854 A IL 258854A IL 25885418 A IL25885418 A IL 25885418A IL 258854 B2 IL258854 B2 IL 258854B2
Authority
IL
Israel
Prior art keywords
cancer
cbd
cheh
aebs
cannabidiol
Prior art date
Application number
IL258854A
Other languages
English (en)
Hebrew (he)
Other versions
IL258854A (en
IL258854B1 (en
Original Assignee
Jay Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jay Pharma Inc filed Critical Jay Pharma Inc
Publication of IL258854A publication Critical patent/IL258854A/en
Publication of IL258854B1 publication Critical patent/IL258854B1/en
Publication of IL258854B2 publication Critical patent/IL258854B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL258854A 2015-10-27 2016-10-27 Preparations containing cannabidiol and secondary pharmacological agents for cancer treatment IL258854B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562246780P 2015-10-27 2015-10-27
PCT/IL2016/051166 WO2017072773A1 (en) 2015-10-27 2016-10-27 Compositions comprising cannabidiol and second therapeutic agents for the treatment of cancer

Publications (3)

Publication Number Publication Date
IL258854A IL258854A (en) 2018-06-28
IL258854B1 IL258854B1 (en) 2025-02-01
IL258854B2 true IL258854B2 (en) 2025-06-01

Family

ID=57406292

Family Applications (1)

Application Number Title Priority Date Filing Date
IL258854A IL258854B2 (en) 2015-10-27 2016-10-27 Preparations containing cannabidiol and secondary pharmacological agents for cancer treatment

Country Status (10)

Country Link
US (1) US11090275B2 (enExample)
EP (1) EP3368024B1 (enExample)
JP (1) JP7078538B2 (enExample)
KR (1) KR20180102053A (enExample)
CN (1) CN109310648B (enExample)
AU (1) AU2016347662B2 (enExample)
BR (1) BR112018008601A2 (enExample)
CA (2) CA3187317A1 (enExample)
IL (1) IL258854B2 (enExample)
WO (1) WO2017072773A1 (enExample)

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WO2020161083A1 (en) * 2019-02-04 2020-08-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for modulating blood-brain barrier
MX2022000027A (es) * 2019-07-02 2022-04-11 Ellevet Sciences Extracto de ca?amo para tratamiento del dolor, cancer y epilepsia en animales.
EP3826630B1 (en) * 2019-07-21 2022-06-29 SCF Pharma Inc. Cannabinoids compositions with polyunsaturated fatty acid monoglycerides and use thereof
WO2021203206A1 (en) * 2020-04-09 2021-10-14 Laviolette Steven Robert Combination of cannabidiol and a ppar agonist
CN111773390B (zh) * 2020-07-01 2021-08-20 南京大学 一种药物在制备治疗脑转移瘤及其相关疾病的药品中的应用
CN113368085A (zh) * 2021-06-05 2021-09-10 昆明医科大学第一附属医院 大麻二酚在调节肿瘤微生态治疗乳腺癌药物研制中的应用
CN113384563A (zh) * 2021-06-16 2021-09-14 冯敏 大麻二酚在制备治疗非霍奇金淋巴瘤的药物中的应用
KR20240116462A (ko) 2021-10-26 2024-07-29 더 유니버시티 오브 뉴캐슬 대마 추출물로 난소암을 치료하는 방법
CA3235077A1 (en) 2021-10-26 2023-05-04 Alex Nance Systems and methods for producing hemp extracts and compositions
AU2022379618A1 (en) 2021-10-26 2024-05-23 Dove Innovation Pty Limited Methods of treating endometriosis and other non-cancer gynecological disorders with hemp extract
US12440454B2 (en) 2022-02-01 2025-10-14 Portland Technology Holdings Llc Pharmaceutical compositions containing hemp extract for administration to felines and related methods
EP4548102A1 (en) * 2022-06-30 2025-05-07 Univerza v Mariboru Cannabinoid compositions against cancer, their identification and personalization of cannabis-based cancer therapy
US20240009211A1 (en) * 2022-07-05 2024-01-11 Neocannbio Co., Ltd. Pharmaceutical composition for treatment of lung cancer comprising cannabidiol and anticancer agent as active ingredients, and use thereof
KR20240036953A (ko) * 2022-09-14 2024-03-21 주식회사 네오켄바이오 칸나비디올 및 항암제를 유효성분으로 포함하는 간암 치료용 약학 조성물 및 이의 용도
US12097211B2 (en) 2022-10-26 2024-09-24 Ecofibre USA Inc. Methods of treating estrogen sensitive diseases with cannabis extract
US12011451B2 (en) 2022-10-26 2024-06-18 Ecofibre USA Inc. Stabilized compositions comprising cannabidiol
WO2024097631A2 (en) * 2022-11-02 2024-05-10 Morehouse School Of Medicine Methods of treating pain and drepression

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2460672A (en) * 2008-06-04 2009-12-09 Gw Pharma Ltd Cancer medication using cannabinoids in combination with non-cannabinoids

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Also Published As

Publication number Publication date
AU2016347662A1 (en) 2018-05-10
EP3368024B1 (en) 2023-09-20
US11090275B2 (en) 2021-08-17
IL258854A (en) 2018-06-28
JP2018536706A (ja) 2018-12-13
IL258854B1 (en) 2025-02-01
CA3002767C (en) 2023-03-14
CA3187317A1 (en) 2017-05-04
JP7078538B2 (ja) 2022-05-31
CN109310648B (zh) 2022-06-03
BR112018008601A2 (pt) 2018-10-30
CA3002767A1 (en) 2017-05-04
US20180311182A1 (en) 2018-11-01
KR20180102053A (ko) 2018-09-14
WO2017072773A1 (en) 2017-05-04
EP3368024A1 (en) 2018-09-05
CN109310648A (zh) 2019-02-05
AU2016347662B2 (en) 2021-12-02

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