IL252221B - Transformed aromatic compounds and pharmaceutical preparations for self-repair and tissue reconstruction - Google Patents
Transformed aromatic compounds and pharmaceutical preparations for self-repair and tissue reconstructionInfo
- Publication number
- IL252221B IL252221B IL252221A IL25222117A IL252221B IL 252221 B IL252221 B IL 252221B IL 252221 A IL252221 A IL 252221A IL 25222117 A IL25222117 A IL 25222117A IL 252221 B IL252221 B IL 252221B
- Authority
- IL
- Israel
- Prior art keywords
- regeneration
- repair
- pharmaceutical compositions
- aromatic compounds
- substituted aromatic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/32—Phenylacetic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462078704P | 2014-11-12 | 2014-11-12 | |
| PCT/CA2015/000572 WO2016074068A1 (en) | 2014-11-12 | 2015-11-12 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL252221A0 IL252221A0 (en) | 2017-07-31 |
| IL252221B true IL252221B (en) | 2022-04-01 |
Family
ID=55953490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL252221A IL252221B (en) | 2014-11-12 | 2017-05-10 | Transformed aromatic compounds and pharmaceutical preparations for self-repair and tissue reconstruction |
Country Status (19)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI742541B (zh) * | 2013-03-15 | 2021-10-11 | 英商邊緣生物科技有限公司 | 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物 |
| EP3217968A4 (en) * | 2014-11-12 | 2018-06-20 | Prometic Pharma Smt Limited | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2289417C1 (ru) * | 2005-04-15 | 2006-12-20 | Равиль Шамилевич Мирхайдаров | Способ биологического омоложения кожи |
| EP1953222A1 (en) * | 2007-01-24 | 2008-08-06 | Boehringer Ingelheim Pharma GmbH & Co. KG | Improvement of cell growth |
| BRPI1015124B8 (pt) | 2009-05-04 | 2021-05-25 | Prometic Biosciences Inc | compostos aromáticos substituídos para a prevenção ou tratamento de distúrbios sanguíneos; distúrbios renais, nefropatias e/ou complicações do distúrbio renal; doenças relacionadas com inflamação; e distúrbios relacionados ao estresse oxidativo, usos farmacêuticos dos mesmos e composição farmacêutica comprendendo ditos compostos |
| JP5844251B2 (ja) * | 2009-05-04 | 2016-01-13 | プロメティック・バイオサイエンシーズ・インコーポレイテッドＰｒｏＭｅｔｉｃ ＢｉｏＳｃｉｅｎｃｅｓ Ｉｎｃ． | ３−ペンチルフェニル酢酸の塩およびその薬学的使用 |
| ES2351005B1 (es) * | 2009-07-10 | 2011-11-18 | Consejo Superior De Investigaciones Científicas (Csic) | Uso de anhidrasa carbónica ii para la elaboración de un medicamento. |
| PT2632885T (pt) | 2010-10-27 | 2018-04-04 | Prometic Pharma Smt Ltd | Compostos carboxilatos de fenilcetona e usos farmacêuticos destes |
| WO2012097428A1 (en) * | 2010-10-27 | 2012-07-26 | Prometic Biosciences Inc. | Compounds and pharmaceutical compositions for uses in diabetes |
| KR101821646B1 (ko) | 2010-10-27 | 2018-01-25 | 프로메틱 파마 에스엠티 리미티드 | 암을 치료하기 위한 화합물 및 조성물 |
| JP5388233B2 (ja) * | 2011-01-19 | 2014-01-15 | 富士ソフト株式会社 | 再生軟骨の軟骨特性を評価する方法 |
| CA2844792A1 (en) * | 2011-08-10 | 2013-02-14 | Digna Biotech, S.L. | Use of cardiotrophin-1 for the treatment of kidney diseases |
| TWI689490B (zh) * | 2013-03-15 | 2020-04-01 | 英商邊緣生物科技有限公司 | 用於治療纖維化之經取代之芳族化合物及相關方法 |
| TWI742541B (zh) | 2013-03-15 | 2021-10-11 | 英商邊緣生物科技有限公司 | 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物 |
| PH12017500662B1 (en) | 2014-10-10 | 2022-08-19 | Liminal Biosciences Ltd | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of diabetes |
| MY194308A (en) | 2014-10-10 | 2022-11-27 | Prometic Pharma Smt Ltd | Substituted aromatic compounds and pharmaceutical compostions for the prevention and treatment of osteoporosis |
| EP3217968A4 (en) * | 2014-11-12 | 2018-06-20 | Prometic Pharma Smt Limited | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration |
-
2015
- 2015-11-12 EP EP15859768.2A patent/EP3217968A4/en not_active Withdrawn
- 2015-11-12 CN CN201580071284.6A patent/CN107106526B/zh not_active Expired - Fee Related
- 2015-11-12 TW TW104137375A patent/TWI723967B/zh not_active IP Right Cessation
- 2015-11-12 SG SG11201703741TA patent/SG11201703741TA/en unknown
- 2015-11-12 CA CA2967499A patent/CA2967499C/en active Active
- 2015-11-12 JP JP2017525587A patent/JP6720169B2/ja not_active Expired - Fee Related
- 2015-11-12 RU RU2017120401A patent/RU2728782C2/ru active
- 2015-11-12 MY MYPI2017000688A patent/MY187515A/en unknown
- 2015-11-12 AU AU2015345943A patent/AU2015345943B2/en not_active Ceased
- 2015-11-12 US US15/526,405 patent/US10391073B2/en not_active Expired - Fee Related
- 2015-11-12 KR KR1020177015741A patent/KR20170072352A/ko not_active Ceased
- 2015-11-12 WO PCT/CA2015/000572 patent/WO2016074068A1/en not_active Ceased
- 2015-11-12 MX MX2017006281A patent/MX381687B/es unknown
- 2015-11-12 AR ARP150103693A patent/AR102634A1/es unknown
- 2015-11-12 UY UY0001036399A patent/UY36399A/es unknown
- 2015-11-12 BR BR112017009899A patent/BR112017009899A2/pt active Search and Examination
-
2017
- 2017-05-08 PH PH12017500856A patent/PH12017500856A1/en unknown
- 2017-05-10 IL IL252221A patent/IL252221B/en unknown
- 2017-05-24 ZA ZA2017/03579A patent/ZA201703579B/en unknown
-
2019
- 2019-07-12 US US16/510,581 patent/US10869849B2/en active Active
-
2020
- 2020-06-19 AU AU2020204112A patent/AU2020204112B2/en not_active Ceased
- 2020-12-03 US US17/111,146 patent/US20210085626A1/en not_active Abandoned
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