IL252192A0 - דיאנהידרוגאלאקטיטול יחד עם קרינה לטיפול בתאים לא קטנטנים של סרטן הריאה ו גליאובלסטומה רב-צורנית - Google Patents
דיאנהידרוגאלאקטיטול יחד עם קרינה לטיפול בתאים לא קטנטנים של סרטן הריאה ו גליאובלסטומה רב-צורניתInfo
- Publication number
- IL252192A0 IL252192A0 IL252192A IL25219217A IL252192A0 IL 252192 A0 IL252192 A0 IL 252192A0 IL 252192 A IL252192 A IL 252192A IL 25219217 A IL25219217 A IL 25219217A IL 252192 A0 IL252192 A0 IL 252192A0
- Authority
- IL
- Israel
- Prior art keywords
- dianhydrogalactitol
- lung
- radiation
- small
- cell carcinoma
- Prior art date
Links
- AAFJXZWCNVJTMK-GUCUJZIJSA-N (1s,2r)-1-[(2s)-oxiran-2-yl]-2-[(2r)-oxiran-2-yl]ethane-1,2-diol Chemical compound C([C@@H]1[C@H](O)[C@H](O)[C@H]2OC2)O1 AAFJXZWCNVJTMK-GUCUJZIJSA-N 0.000 title 1
- 201000010915 Glioblastoma multiforme Diseases 0.000 title 1
- 229950000758 dianhydrogalactitol Drugs 0.000 title 1
- 208000005017 glioblastoma Diseases 0.000 title 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 title 1
- 230000005855 radiation Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462077712P | 2014-11-10 | 2014-11-10 | |
| PCT/US2015/059814 WO2016077264A1 (en) | 2014-11-10 | 2015-11-10 | Dianhydrogalactitol together with radiation to treat non-small-cell carcinoma of the lung and glioblastoma multiforme |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL252192A0 true IL252192A0 (he) | 2017-07-31 |
| IL252192B1 IL252192B1 (he) | 2023-11-01 |
| IL252192B2 IL252192B2 (he) | 2024-03-01 |
Family
ID=55954912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL252192A IL252192B2 (he) | 2014-11-10 | 2015-11-10 | דיאנהידרוגאלאקטיטול יחד עם קרינה לטיפול בתאים לא קטנטנים של סרטן הריאה ו גליאובלסטומה רב–צורנית |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20190015379A1 (he) |
| EP (1) | EP3217970A4 (he) |
| JP (3) | JP2017536356A (he) |
| KR (2) | KR20170081261A (he) |
| CN (2) | CN115414480A (he) |
| AU (1) | AU2015346598B2 (he) |
| BR (1) | BR112017009845A2 (he) |
| CA (1) | CA2967322A1 (he) |
| CL (1) | CL2017001180A1 (he) |
| IL (1) | IL252192B2 (he) |
| MX (1) | MX2017006076A (he) |
| SG (1) | SG11201703810QA (he) |
| TW (1) | TW201632181A (he) |
| WO (1) | WO2016077264A1 (he) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115414480A (zh) * | 2014-11-10 | 2022-12-02 | 德玛医药 | 结合放射用于治疗非小细胞肺癌和多形性胶质母细胞瘤的二去水卫矛醇 |
| US11715549B2 (en) * | 2017-05-01 | 2023-08-01 | Thomas Jefferson University | Systems-level analysis of 32 TCGA cancers reveals disease-dependent tRNA fragmentation patterns and very selective associations with messenger RNAs and repeat elements |
| JP2020530453A (ja) | 2017-08-09 | 2020-10-22 | マサチューセッツ インスティテュート オブ テクノロジー | アルブミン結合ペプチド結合体及びその方法 |
| CN109512833B (zh) * | 2018-12-04 | 2020-10-30 | 天津医科大学总医院 | E2f6抑制剂的功能与用途 |
| WO2021207650A1 (en) * | 2020-04-09 | 2021-10-14 | L.E.A.F. Holdings Group Llc | Trans-crocetin compositions and treatment regimens |
| KR102560912B1 (ko) * | 2020-08-26 | 2023-07-28 | 한양대학교 에리카산학협력단 | 엑소좀을 유효성분으로 포함하는 폐암 치료, 예방 또는 전이 억제용 약학적 조성물 |
| CN113599524B (zh) * | 2021-09-02 | 2023-05-02 | 中国医学科学院肿瘤医院 | Hnrnpc和rbmx作为靶点在制备治疗小细胞肺癌的产品中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801575A (en) * | 1986-07-30 | 1989-01-31 | The Regents Of The University Of California | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
| US4938949A (en) * | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| EP3730139B1 (en) * | 2008-06-17 | 2023-08-16 | Wyeth LLC | Antineoplastic combinations containing hki-272 and vinorelbine |
| WO2012024367A2 (en) * | 2010-08-18 | 2012-02-23 | Del Mar Pharmaceuticals | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol |
| US10201521B2 (en) * | 2012-01-20 | 2019-02-12 | Del Mar Pharmaceuticals (Bc) Ltd. | Use of substituted hexitols including dianhydrogalactitol and analogs to treat neoplastic disease and cancer stem and cancer stem cells including glioblastoma multiforme and medulloblastoma |
| CN106659765B (zh) * | 2014-04-04 | 2021-08-13 | 德玛医药 | 二脱水半乳糖醇及其类似物或衍生物用于治疗非小细胞肺癌和卵巢癌的用途 |
| CN115414480A (zh) * | 2014-11-10 | 2022-12-02 | 德玛医药 | 结合放射用于治疗非小细胞肺癌和多形性胶质母细胞瘤的二去水卫矛醇 |
-
2015
- 2015-11-10 CN CN202211009952.0A patent/CN115414480A/zh active Pending
- 2015-11-10 MX MX2017006076A patent/MX2017006076A/es unknown
- 2015-11-10 SG SG11201703810QA patent/SG11201703810QA/en unknown
- 2015-11-10 EP EP15858948.1A patent/EP3217970A4/en active Pending
- 2015-11-10 CN CN201580071196.6A patent/CN107231794A/zh active Pending
- 2015-11-10 KR KR1020177015926A patent/KR20170081261A/ko not_active Application Discontinuation
- 2015-11-10 KR KR1020227046292A patent/KR20230008252A/ko not_active Application Discontinuation
- 2015-11-10 BR BR112017009845A patent/BR112017009845A2/pt not_active Application Discontinuation
- 2015-11-10 TW TW104136993A patent/TW201632181A/zh unknown
- 2015-11-10 AU AU2015346598A patent/AU2015346598B2/en active Active
- 2015-11-10 WO PCT/US2015/059814 patent/WO2016077264A1/en active Application Filing
- 2015-11-10 CA CA2967322A patent/CA2967322A1/en active Pending
- 2015-11-10 IL IL252192A patent/IL252192B2/he unknown
- 2015-11-10 JP JP2017525080A patent/JP2017536356A/ja active Pending
- 2015-11-10 US US15/525,933 patent/US20190015379A1/en not_active Abandoned
-
2017
- 2017-05-10 CL CL2017001180A patent/CL2017001180A1/es unknown
-
2020
- 2020-07-30 JP JP2020129093A patent/JP2020183445A/ja active Pending
-
2022
- 2022-09-08 JP JP2022142672A patent/JP2022174200A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015346598A1 (en) | 2017-06-08 |
| BR112017009845A2 (pt) | 2018-01-16 |
| SG11201703810QA (en) | 2017-06-29 |
| CL2017001180A1 (es) | 2017-12-29 |
| WO2016077264A1 (en) | 2016-05-19 |
| KR20230008252A (ko) | 2023-01-13 |
| US20190015379A1 (en) | 2019-01-17 |
| MX2017006076A (es) | 2017-12-11 |
| CN107231794A (zh) | 2017-10-03 |
| JP2022174200A (ja) | 2022-11-22 |
| IL252192B1 (he) | 2023-11-01 |
| EP3217970A4 (en) | 2018-07-18 |
| KR20170081261A (ko) | 2017-07-11 |
| CA2967322A1 (en) | 2016-05-19 |
| JP2020183445A (ja) | 2020-11-12 |
| IL252192B2 (he) | 2024-03-01 |
| TW201632181A (zh) | 2016-09-16 |
| JP2017536356A (ja) | 2017-12-07 |
| AU2015346598B2 (en) | 2020-09-03 |
| EP3217970A1 (en) | 2017-09-20 |
| CN115414480A (zh) | 2022-12-02 |
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