IL252192A0 - דיאנהידרוגאלאקטיטול יחד עם קרינה לטיפול בתאים לא קטנטנים של סרטן הריאה ו גליאובלסטומה רב-צורנית - Google Patents
דיאנהידרוגאלאקטיטול יחד עם קרינה לטיפול בתאים לא קטנטנים של סרטן הריאה ו גליאובלסטומה רב-צורניתInfo
- Publication number
- IL252192A0 IL252192A0 IL252192A IL25219217A IL252192A0 IL 252192 A0 IL252192 A0 IL 252192A0 IL 252192 A IL252192 A IL 252192A IL 25219217 A IL25219217 A IL 25219217A IL 252192 A0 IL252192 A0 IL 252192A0
- Authority
- IL
- Israel
- Prior art keywords
- dianhydrogalactitol
- lung
- radiation
- small
- cell carcinoma
- Prior art date
Links
- AAFJXZWCNVJTMK-GUCUJZIJSA-N (1s,2r)-1-[(2s)-oxiran-2-yl]-2-[(2r)-oxiran-2-yl]ethane-1,2-diol Chemical compound C([C@@H]1[C@H](O)[C@H](O)[C@H]2OC2)O1 AAFJXZWCNVJTMK-GUCUJZIJSA-N 0.000 title 1
- 201000010915 Glioblastoma multiforme Diseases 0.000 title 1
- 229950000758 dianhydrogalactitol Drugs 0.000 title 1
- 208000005017 glioblastoma Diseases 0.000 title 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 title 1
- 230000005855 radiation Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462077712P | 2014-11-10 | 2014-11-10 | |
| PCT/US2015/059814 WO2016077264A1 (en) | 2014-11-10 | 2015-11-10 | Dianhydrogalactitol together with radiation to treat non-small-cell carcinoma of the lung and glioblastoma multiforme |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL252192A0 true IL252192A0 (he) | 2017-07-31 |
| IL252192B1 IL252192B1 (he) | 2023-11-01 |
| IL252192B2 IL252192B2 (he) | 2024-03-01 |
Family
ID=55954912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL252192A IL252192B2 (he) | 2014-11-10 | 2015-11-10 | דיאנהידרוגאלאקטיטול יחד עם קרינה לטיפול בתאים לא קטנטנים של סרטן הריאה ו גליאובלסטומה רב–צורנית |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20190015379A1 (he) |
| EP (1) | EP3217970A4 (he) |
| JP (3) | JP2017536356A (he) |
| KR (2) | KR20170081261A (he) |
| CN (2) | CN107231794A (he) |
| AU (1) | AU2015346598B2 (he) |
| BR (1) | BR112017009845A2 (he) |
| CA (1) | CA2967322A1 (he) |
| CL (1) | CL2017001180A1 (he) |
| IL (1) | IL252192B2 (he) |
| MX (1) | MX2017006076A (he) |
| SG (1) | SG11201703810QA (he) |
| TW (1) | TW201632181A (he) |
| WO (1) | WO2016077264A1 (he) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190015379A1 (en) * | 2014-11-10 | 2019-01-17 | Delmar Pharmaceuticals, Inc. | Use of dianhydrogalactitol and analogs and derivatives thereof, together with radiation, to treat non-small-cell carcinoma of the lung and glioblastoma multiforme and suppress proliferation of cancer stem cells |
| US11715549B2 (en) * | 2017-05-01 | 2023-08-01 | Thomas Jefferson University | Systems-level analysis of 32 TCGA cancers reveals disease-dependent tRNA fragmentation patterns and very selective associations with messenger RNAs and repeat elements |
| CN111164104A (zh) | 2017-08-09 | 2020-05-15 | 麻省理工学院 | 白蛋白结合肽缀合物及其方法 |
| CN109512833B (zh) * | 2018-12-04 | 2020-10-30 | 天津医科大学总医院 | E2f6抑制剂的功能与用途 |
| US20230210803A1 (en) * | 2020-04-09 | 2023-07-06 | L.E.A.F. Holdings Group Llc | Trans-crocetin compositions and treatment regimens |
| KR102560912B1 (ko) * | 2020-08-26 | 2023-07-28 | 한양대학교 에리카산학협력단 | 엑소좀을 유효성분으로 포함하는 폐암 치료, 예방 또는 전이 억제용 약학적 조성물 |
| CN113599524B (zh) * | 2021-09-02 | 2023-05-02 | 中国医学科学院肿瘤医院 | Hnrnpc和rbmx作为靶点在制备治疗小细胞肺癌的产品中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801575A (en) * | 1986-07-30 | 1989-01-31 | The Regents Of The University Of California | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
| US4938949A (en) * | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| PL2310011T3 (pl) * | 2008-06-17 | 2013-12-31 | Wyeth Llc | Kombinacje przeciwnowotworowe zawierające HKI-272 i vinorelbine |
| KR20140022750A (ko) * | 2010-08-18 | 2014-02-25 | 델 마 파마슈티컬스 인코포레이티드 | 디안하이드로갈락티톨 및 디아세틸디안하이드로갈락티톨과 같은 치환된 헥시톨을 포함하는 준최적하게 투여되는 화학적 화합물의 치료상 이점을 향상시키기 위한 조성물 및 방법 |
| BR112014017833A2 (pt) * | 2012-01-20 | 2021-03-23 | Dennis Brown | Uso de hexitóis substituídos incluindo dianidrogalactitol e análogos para tratar doença neoplástica e células-tronco de câncer incluindo glioblastoma multiforme e meduloblastoma |
| CN106659765B (zh) * | 2014-04-04 | 2021-08-13 | 德玛医药 | 二脱水半乳糖醇及其类似物或衍生物用于治疗非小细胞肺癌和卵巢癌的用途 |
| US20190015379A1 (en) * | 2014-11-10 | 2019-01-17 | Delmar Pharmaceuticals, Inc. | Use of dianhydrogalactitol and analogs and derivatives thereof, together with radiation, to treat non-small-cell carcinoma of the lung and glioblastoma multiforme and suppress proliferation of cancer stem cells |
-
2015
- 2015-11-10 US US15/525,933 patent/US20190015379A1/en not_active Abandoned
- 2015-11-10 CN CN201580071196.6A patent/CN107231794A/zh active Pending
- 2015-11-10 EP EP15858948.1A patent/EP3217970A4/en active Pending
- 2015-11-10 TW TW104136993A patent/TW201632181A/zh unknown
- 2015-11-10 BR BR112017009845A patent/BR112017009845A2/pt not_active Application Discontinuation
- 2015-11-10 KR KR1020177015926A patent/KR20170081261A/ko not_active Application Discontinuation
- 2015-11-10 AU AU2015346598A patent/AU2015346598B2/en active Active
- 2015-11-10 MX MX2017006076A patent/MX2017006076A/es unknown
- 2015-11-10 KR KR1020227046292A patent/KR20230008252A/ko not_active Application Discontinuation
- 2015-11-10 IL IL252192A patent/IL252192B2/he unknown
- 2015-11-10 CN CN202211009952.0A patent/CN115414480A/zh active Pending
- 2015-11-10 SG SG11201703810QA patent/SG11201703810QA/en unknown
- 2015-11-10 WO PCT/US2015/059814 patent/WO2016077264A1/en active Application Filing
- 2015-11-10 CA CA2967322A patent/CA2967322A1/en active Pending
- 2015-11-10 JP JP2017525080A patent/JP2017536356A/ja active Pending
-
2017
- 2017-05-10 CL CL2017001180A patent/CL2017001180A1/es unknown
-
2020
- 2020-07-30 JP JP2020129093A patent/JP2020183445A/ja active Pending
-
2022
- 2022-09-08 JP JP2022142672A patent/JP2022174200A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20170081261A (ko) | 2017-07-11 |
| CA2967322A1 (en) | 2016-05-19 |
| EP3217970A1 (en) | 2017-09-20 |
| KR20230008252A (ko) | 2023-01-13 |
| TW201632181A (zh) | 2016-09-16 |
| CN115414480A (zh) | 2022-12-02 |
| SG11201703810QA (en) | 2017-06-29 |
| JP2020183445A (ja) | 2020-11-12 |
| AU2015346598A1 (en) | 2017-06-08 |
| EP3217970A4 (en) | 2018-07-18 |
| IL252192B2 (he) | 2024-03-01 |
| MX2017006076A (es) | 2017-12-11 |
| US20190015379A1 (en) | 2019-01-17 |
| IL252192B1 (he) | 2023-11-01 |
| WO2016077264A1 (en) | 2016-05-19 |
| BR112017009845A2 (pt) | 2018-01-16 |
| CL2017001180A1 (es) | 2017-12-29 |
| JP2022174200A (ja) | 2022-11-22 |
| JP2017536356A (ja) | 2017-12-07 |
| CN107231794A (zh) | 2017-10-03 |
| AU2015346598B2 (en) | 2020-09-03 |
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