IL249823B - Meningococcus vaccines - Google Patents

Meningococcus vaccines

Info

Publication number
IL249823B
IL249823B IL249823A IL24982316A IL249823B IL 249823 B IL249823 B IL 249823B IL 249823 A IL249823 A IL 249823A IL 24982316 A IL24982316 A IL 24982316A IL 249823 B IL249823 B IL 249823B
Authority
IL
Israel
Prior art keywords
seq
fhbp
amino acid
polypeptide
acid sequence
Prior art date
Application number
IL249823A
Other languages
English (en)
Hebrew (he)
Other versions
IL249823A0 (en
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of IL249823A0 publication Critical patent/IL249823A0/en
Publication of IL249823B publication Critical patent/IL249823B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/116—Polyvalent bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
IL249823A 2014-07-17 2015-07-16 Meningococcus vaccines IL249823B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14177563 2014-07-17
PCT/EP2015/066229 WO2016008961A1 (en) 2014-07-17 2015-07-16 Meningococcus vaccines

Publications (2)

Publication Number Publication Date
IL249823A0 IL249823A0 (en) 2017-03-30
IL249823B true IL249823B (en) 2022-07-01

Family

ID=51178811

Family Applications (1)

Application Number Title Priority Date Filing Date
IL249823A IL249823B (en) 2014-07-17 2015-07-16 Meningococcus vaccines

Country Status (15)

Country Link
US (2) US11707513B2 (enExample)
EP (1) EP3169358A1 (enExample)
JP (2) JP6687597B2 (enExample)
KR (2) KR20230012100A (enExample)
CN (2) CN113827712A (enExample)
AR (2) AR101225A1 (enExample)
AU (2) AU2015289193A1 (enExample)
BE (1) BE1022878B1 (enExample)
BR (1) BR112017000519A2 (enExample)
CA (1) CA2954729C (enExample)
EA (1) EA038940B1 (enExample)
IL (1) IL249823B (enExample)
MX (1) MX2017000775A (enExample)
SG (2) SG10201900041VA (enExample)
WO (1) WO2016008961A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6786394B2 (ja) 2014-02-28 2020-11-18 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変髄膜炎菌ｆＨｂｐポリペプチド
EA201692552A1 (ru) 2014-07-17 2017-06-30 Глаксосмитклайн Байолоджикалс С.А. МОДИФИЦИРОВАННЫЕ МЕНИНГОКОККОВЫЕ ПОЛИПЕПТИДЫ fHbp
CA2954729C (en) 2014-07-17 2023-08-22 Glaxosmithkline Biologicals S.A. Meningococcus vaccines
WO2017075189A1 (en) * 2015-10-27 2017-05-04 University Of Massachusetts Factor h-fc immunotherapy
CN107961369B (zh) * 2017-03-22 2020-08-11 武汉博沃生物科技有限公司 多价脑膜炎球菌缀合疫苗及其制备方法
CN108939061A (zh) * 2018-08-03 2018-12-07 北京智飞绿竹生物制药有限公司 一种多组分b群脑膜炎球菌疫苗及其制备方法
EP3607967A1 (en) * 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
US11014736B2 (en) 2019-04-18 2021-05-25 Altria Client Services Llc Sliding packs with flip top hinged lids
CN110804101A (zh) * 2019-11-08 2020-02-18 苏州微超生物科技有限公司 B群脑膜炎球菌相关融合蛋白、疫苗及其制备方法与应用
CN115348968A (zh) * 2019-11-25 2022-11-15 格里菲斯大学 针对淋球菌感染的免疫原性蛋白
GB202115151D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Methods
WO2025077785A1 (zh) * 2023-10-10 2025-04-17 康希诺生物股份公司 一种抗脑膜炎球菌的免疫组合物及其用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004048404A2 (en) * 2002-11-22 2004-06-10 Chiron Srl Multiple variants of meningococcal protein nmb1870
WO2006024954A2 (en) * 2004-09-01 2006-03-09 Novartis Vaccines And Diagnostics Srl Domains and epitopes of meningococcal protein nmb1870
WO2007060548A2 (en) * 2005-11-25 2007-05-31 Novartis Vaccines And Diagnostics Srl Chimeric, hybrid and tandem polypeptides of meningococcal nmb1870
WO2013186753A1 (en) * 2012-06-14 2013-12-19 Novartis Ag Vaccines for serogroup x meningococcus

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747137B1 (en) 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
US6551795B1 (en) 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
ES2507100T3 (es) * 2000-01-17 2014-10-14 Novartis Vaccines And Diagnostics S.R.L. Vacuna OMV suplementada contra meningococo
GB0419627D0 (en) * 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
AU2010310985B2 (en) 2009-10-27 2014-11-06 Glaxosmithkline Biologicals S.A. Modified meningococcal fHBP polypeptides
US9567377B2 (en) * 2010-03-10 2017-02-14 Glaxosmithkline Biologicals Sa Immunogenic composition
CN105315351A (zh) 2010-03-30 2016-02-10 奥克兰儿童医院及研究中心 改性的h因子结合蛋白（fhbp）及其使用方法
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
GB201120634D0 (en) 2011-11-30 2012-01-11 Univ Sheffield Adjuvant polypeptide
GB201215005D0 (en) 2012-08-23 2012-10-10 Isis Innovation Stabilised meningitis vaccine
JP6786394B2 (ja) * 2014-02-28 2020-11-18 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変髄膜炎菌ｆＨｂｐポリペプチド
EP2916512B1 (en) 2014-03-07 2016-08-24 Mitsubishi Electric R&D Centre Europe B.V. Method for classifying a TCP connection carrying HTTP traffic as a trusted or an untrusted TCP connection
CA2954729C (en) 2014-07-17 2023-08-22 Glaxosmithkline Biologicals S.A. Meningococcus vaccines
EA201692552A1 (ru) 2014-07-17 2017-06-30 Глаксосмитклайн Байолоджикалс С.А. МОДИФИЦИРОВАННЫЕ МЕНИНГОКОККОВЫЕ ПОЛИПЕПТИДЫ fHbp
ES2990193T3 (es) 2018-06-21 2024-11-29 Basf Se Derivados de difosfato de 3-fenilbenzofuran-2-ona como estabilizadores

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004048404A2 (en) * 2002-11-22 2004-06-10 Chiron Srl Multiple variants of meningococcal protein nmb1870
WO2006024954A2 (en) * 2004-09-01 2006-03-09 Novartis Vaccines And Diagnostics Srl Domains and epitopes of meningococcal protein nmb1870
WO2007060548A2 (en) * 2005-11-25 2007-05-31 Novartis Vaccines And Diagnostics Srl Chimeric, hybrid and tandem polypeptides of meningococcal nmb1870
WO2013186753A1 (en) * 2012-06-14 2013-12-19 Novartis Ag Vaccines for serogroup x meningococcus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ESPOSITO SUSANNA ET AL, A PHASE II RANDOMIZED CONTROLLED TRIAL OF A MULTICOMPONENT MENINGOCOCCAL SEROGROUP B VACCINE, 4CMENB, IN INFANTS (II), 11 July 2014 (2014-07-11) *

Also Published As

Publication number Publication date
CA2954729A1 (en) 2016-01-21
AU2019201131A1 (en) 2019-03-07
US20230414736A1 (en) 2023-12-28
EA201692554A1 (ru) 2017-07-31
BR112017000519A2 (pt) 2017-11-21
JP2017522319A (ja) 2017-08-10
JP2020117523A (ja) 2020-08-06
CN113827712A (zh) 2021-12-24
AR130778A2 (es) 2025-01-15
AU2015289193A1 (en) 2017-02-02
JP6687597B2 (ja) 2020-04-22
AR101225A1 (es) 2016-11-30
KR20170029615A (ko) 2017-03-15
JP7074793B2 (ja) 2022-05-24
BE1022878A1 (fr) 2016-09-30
US12485164B2 (en) 2025-12-02
WO2016008961A1 (en) 2016-01-21
EA038940B1 (ru) 2021-11-12
MX2017000775A (es) 2017-05-04
IL249823A0 (en) 2017-03-30
AU2019201131B2 (en) 2020-08-27
US20180214531A1 (en) 2018-08-02
BE1022878B1 (fr) 2016-09-30
EP3169358A1 (en) 2017-05-24
US11707513B2 (en) 2023-07-25
CA2954729C (en) 2023-08-22
KR20230012100A (ko) 2023-01-25
SG10201900041VA (en) 2019-02-27
KR102626831B1 (ko) 2024-01-22
AU2019201131C1 (en) 2021-03-18
SG11201610946YA (en) 2017-01-27
CN106659776A (zh) 2017-05-10

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