IL246162B - Angiotensin II, alone or in combination, to treat low blood pressure - Google Patents
Angiotensin II, alone or in combination, to treat low blood pressureInfo
- Publication number
- IL246162B IL246162B IL246162A IL24616216A IL246162B IL 246162 B IL246162 B IL 246162B IL 246162 A IL246162 A IL 246162A IL 24616216 A IL24616216 A IL 24616216A IL 246162 B IL246162 B IL 246162B
- Authority
- IL
- Israel
- Prior art keywords
- hypotension
- angiotensin
- alone
- treatment
- combination
- Prior art date
Links
- 102000005862 Angiotensin II Human genes 0.000 title 1
- 101800000733 Angiotensin-2 Proteins 0.000 title 1
- 208000001953 Hypotension Diseases 0.000 title 1
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 title 1
- 229950006323 angiotensin ii Drugs 0.000 title 1
- 230000036543 hypotension Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361917576P | 2013-12-18 | 2013-12-18 | |
| US201461955706P | 2014-03-19 | 2014-03-19 | |
| PCT/US2014/071186 WO2015095535A1 (en) | 2013-12-18 | 2014-12-18 | Angiotensin ii alone or in combination for the treatment of hypotension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL246162A0 IL246162A0 (en) | 2016-07-31 |
| IL246162B true IL246162B (en) | 2020-03-31 |
Family
ID=53367119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL246162A IL246162B (en) | 2013-12-18 | 2016-06-09 | Angiotensin II, alone or in combination, to treat low blood pressure |
Country Status (25)
| Country | Link |
|---|---|
| US (7) | US9220745B2 (OSRAM) |
| EP (2) | EP2986308B1 (OSRAM) |
| JP (4) | JP6824739B2 (OSRAM) |
| KR (4) | KR20220028125A (OSRAM) |
| CN (4) | CN112546197A (OSRAM) |
| AU (3) | AU2014364528C1 (OSRAM) |
| BR (1) | BR112016013961A2 (OSRAM) |
| CA (1) | CA2933601A1 (OSRAM) |
| CY (1) | CY1122604T1 (OSRAM) |
| DK (2) | DK3607962T3 (OSRAM) |
| EA (1) | EA037823B1 (OSRAM) |
| ES (1) | ES2771749T3 (OSRAM) |
| FI (1) | FI3607962T3 (OSRAM) |
| HR (1) | HRP20200009T1 (OSRAM) |
| HU (1) | HUE047062T2 (OSRAM) |
| IL (1) | IL246162B (OSRAM) |
| LT (1) | LT2986308T (OSRAM) |
| MX (2) | MX380968B (OSRAM) |
| NZ (1) | NZ721089A (OSRAM) |
| PL (1) | PL2986308T3 (OSRAM) |
| PT (2) | PT3607962T (OSRAM) |
| RS (1) | RS59804B1 (OSRAM) |
| SI (1) | SI2986308T1 (OSRAM) |
| SM (1) | SMT202000018T1 (OSRAM) |
| WO (1) | WO2015095535A1 (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9572856B2 (en) | 2009-12-16 | 2017-02-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Method of treating low blood pressure |
| HRP20200009T1 (hr) | 2013-12-18 | 2020-03-20 | The George Washington University, A Congressionally Chartered Not-For-Profit Corporation | Angiotenzin ii u kombinaciji za liječenje hipotenzije |
| EA036514B1 (ru) * | 2014-07-08 | 2020-11-18 | Ла Хойя Фарма, Ллк | Способ лечения гипотонии |
| WO2016153558A1 (en) | 2015-03-20 | 2016-09-29 | Atkinson Arthur J | Use of angiotensin ii (aii) receptor agonists to prevent or reduce hemodialysis-associated skeletal muscle cramps |
| WO2017120440A1 (en) * | 2016-01-07 | 2017-07-13 | La Jolla Pharmaceutical Company | Methods of administering vasopressors |
| KR20180108639A (ko) | 2016-01-07 | 2018-10-04 | 라 졸라 파마슈티칼 컴파니 | 안지오텐신 ii를 투여하는 방법 |
| WO2018191678A1 (en) * | 2017-04-14 | 2018-10-18 | La Jolla Pharmaceutical Company | Methods for administering angiotensin ii |
| WO2019118874A1 (en) * | 2017-12-15 | 2019-06-20 | La Jolla Pharma, Llc | Angiotensin compositions and methods related thereto |
| US20250366467A1 (en) * | 2022-06-15 | 2025-12-04 | Virginia Commonwealth University | Methods for fluid resuscitation of an organ donor |
| WO2024129057A1 (en) * | 2022-12-12 | 2024-06-20 | Proletariat Therapeutics, Inc. | Methods of treating cardiac injury |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU181008B (en) | 1980-01-18 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position |
| US5216025A (en) * | 1989-09-13 | 1993-06-01 | Board Of Regents, The University Of Texas System | Nitric oxide synthesis inhibitors for potentiating the action of pressor agents in certain hypotensive patients |
| US5444067A (en) | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
| WO2002098906A1 (en) | 2001-06-04 | 2002-12-12 | Human Genome Sciences, Inc. | Methods and compositions for modulating ace-2 activity |
| US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| NO20034952D0 (no) | 2003-11-06 | 2003-11-06 | Amersham Health As | Farmasöytiske forbindelser |
| JP2007510643A (ja) | 2003-11-06 | 2007-04-26 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 医薬化合物 |
| FR2880807B1 (fr) * | 2005-01-19 | 2007-04-13 | Aguettant Sa Lab | Composition pharmaceutique injectable |
| JP2009510056A (ja) | 2005-09-29 | 2009-03-12 | ファイブローゲン、インコーポレーテッド | 血圧を低下させる方法 |
| WO2007076572A1 (en) | 2005-12-30 | 2007-07-12 | Howard Florey Institute Of Experimental Physiology And Medicine | A method of treatment |
| WO2007146900A2 (en) | 2006-06-15 | 2007-12-21 | Gilead Colorado, Inc. | Antihypertensive therapy method |
| WO2008130217A1 (en) * | 2006-08-08 | 2008-10-30 | Applied Nanosystems B.V. | Cyclic angiotensin analogs |
| BRPI0719319A2 (pt) | 2006-11-17 | 2014-02-04 | Da Volterra | Liberação colônica usando contas de zn/pectina com um revestimento de eudragit |
| WO2009009907A1 (en) * | 2007-07-18 | 2009-01-22 | The University Of British Columbia | Use of vasopressin-receptor agonists for the treatment of septic shock |
| EP2161030A1 (en) * | 2008-09-09 | 2010-03-10 | Rijksuniversiteit te Groningen | Oxytocin formulations and uses thereof |
| JP2012510468A (ja) | 2008-11-28 | 2012-05-10 | アボット・ラボラトリーズ | 安定な抗体組成物およびこれを安定させるための方法 |
| US9572856B2 (en) | 2009-12-16 | 2017-02-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Method of treating low blood pressure |
| FR2959414B1 (fr) * | 2010-04-30 | 2016-01-08 | Luc Quintin | Combinaison de molecules aux fins de traitement d'hypotension survenant au cours du choc septique, cardiogenique, ou anaphylactique refractaire, ou hemorragique terminal, apres correction de la volemie et de l'etat de mal asthmatique refractaire |
| BR112013000744A2 (pt) | 2010-07-14 | 2020-07-14 | Cumberland Emerging Technologies, Inc | uso de um antagonista de receptor de tromboxana a2 para prevenção ou tratamento de síndrome hepatorrenal,encefalopatia hepática,e doenças associadas |
| CA2910601A1 (en) | 2013-04-26 | 2014-10-30 | La Jolla Pharmaceutical Company | Compositions and methods for treating renal failure |
| HRP20200009T1 (hr) | 2013-12-18 | 2020-03-20 | The George Washington University, A Congressionally Chartered Not-For-Profit Corporation | Angiotenzin ii u kombinaciji za liječenje hipotenzije |
| US20150286797A1 (en) | 2014-04-02 | 2015-10-08 | David R. Ratto | System and method for administering medication |
| EA036514B1 (ru) | 2014-07-08 | 2020-11-18 | Ла Хойя Фарма, Ллк | Способ лечения гипотонии |
| KR20180108639A (ko) | 2016-01-07 | 2018-10-04 | 라 졸라 파마슈티칼 컴파니 | 안지오텐신 ii를 투여하는 방법 |
| WO2017120440A1 (en) | 2016-01-07 | 2017-07-13 | La Jolla Pharmaceutical Company | Methods of administering vasopressors |
| WO2018191678A1 (en) | 2017-04-14 | 2018-10-18 | La Jolla Pharmaceutical Company | Methods for administering angiotensin ii |
| WO2019118874A1 (en) | 2017-12-15 | 2019-06-20 | La Jolla Pharma, Llc | Angiotensin compositions and methods related thereto |
-
2014
- 2014-12-18 HR HRP20200009TT patent/HRP20200009T1/hr unknown
- 2014-12-18 NZ NZ721089A patent/NZ721089A/en unknown
- 2014-12-18 DK DK19197866.7T patent/DK3607962T3/da active
- 2014-12-18 DK DK14872684.7T patent/DK2986308T3/da active
- 2014-12-18 AU AU2014364528A patent/AU2014364528C1/en active Active
- 2014-12-18 EP EP14872684.7A patent/EP2986308B1/en active Active
- 2014-12-18 PL PL14872684T patent/PL2986308T3/pl unknown
- 2014-12-18 CN CN202011494632.XA patent/CN112546197A/zh active Pending
- 2014-12-18 KR KR1020227004084A patent/KR20220028125A/ko not_active Ceased
- 2014-12-18 CN CN202411722811.2A patent/CN119700926A/zh active Pending
- 2014-12-18 ES ES14872684T patent/ES2771749T3/es active Active
- 2014-12-18 EA EA201691258A patent/EA037823B1/ru unknown
- 2014-12-18 WO PCT/US2014/071186 patent/WO2015095535A1/en not_active Ceased
- 2014-12-18 PT PT191978667T patent/PT3607962T/pt unknown
- 2014-12-18 CA CA2933601A patent/CA2933601A1/en active Pending
- 2014-12-18 KR KR1020247034828A patent/KR20240154702A/ko active Pending
- 2014-12-18 CN CN201480075899.1A patent/CN106061493A/zh active Pending
- 2014-12-18 MX MX2016008108A patent/MX380968B/es unknown
- 2014-12-18 SM SM20200018T patent/SMT202000018T1/it unknown
- 2014-12-18 BR BR112016013961A patent/BR112016013961A2/pt not_active Application Discontinuation
- 2014-12-18 HU HUE14872684A patent/HUE047062T2/hu unknown
- 2014-12-18 RS RS20200021A patent/RS59804B1/sr unknown
- 2014-12-18 FI FIEP19197866.7T patent/FI3607962T3/fi active
- 2014-12-18 PT PT148726847T patent/PT2986308T/pt unknown
- 2014-12-18 SI SI201431450T patent/SI2986308T1/sl unknown
- 2014-12-18 US US14/575,127 patent/US9220745B2/en active Active
- 2014-12-18 EP EP19197866.7A patent/EP3607962B1/en active Active
- 2014-12-18 KR KR1020167019427A patent/KR102399383B1/ko active Active
- 2014-12-18 LT LTEP14872684.7T patent/LT2986308T/lt unknown
- 2014-12-18 KR KR1020237012136A patent/KR20230051721A/ko not_active Ceased
- 2014-12-18 JP JP2016539318A patent/JP6824739B2/ja active Active
- 2014-12-18 CN CN202010824424.5A patent/CN111920939A/zh active Pending
-
2015
- 2015-11-13 US US14/941,301 patent/US10028995B2/en active Active
-
2016
- 2016-06-09 IL IL246162A patent/IL246162B/en active IP Right Grant
- 2016-06-17 MX MX2020011190A patent/MX2020011190A/es unknown
-
2018
- 2018-03-01 US US15/909,617 patent/US10493124B2/en active Active
- 2018-09-19 US US16/135,608 patent/US10765722B2/en active Active
-
2019
- 2019-04-12 US US16/382,850 patent/US11096983B2/en active Active
- 2019-08-23 JP JP2019153144A patent/JP7175506B2/ja active Active
-
2020
- 2020-01-13 CY CY20201100026T patent/CY1122604T1/el unknown
- 2020-11-26 AU AU2020277230A patent/AU2020277230A1/en not_active Abandoned
-
2021
- 2021-07-20 US US17/380,311 patent/US11559559B2/en active Active
-
2022
- 2022-07-14 JP JP2022113327A patent/JP2022137224A/ja not_active Withdrawn
-
2023
- 2023-01-23 US US18/157,933 patent/US20230226141A1/en not_active Abandoned
-
2024
- 2024-09-18 AU AU2024219851A patent/AU2024219851A1/en active Pending
-
2025
- 2025-05-09 JP JP2025078759A patent/JP2025114753A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |