IL237498B - Drug delivery systems and methods for treating bladder emptying dysfunction and other lower urinary tract disorders using tropesium - Google Patents
Drug delivery systems and methods for treating bladder emptying dysfunction and other lower urinary tract disorders using tropesiumInfo
- Publication number
- IL237498B IL237498B IL237498A IL23749815A IL237498B IL 237498 B IL237498 B IL 237498B IL 237498 A IL237498 A IL 237498A IL 23749815 A IL23749815 A IL 23749815A IL 237498 B IL237498 B IL 237498B
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- methods
- drug delivery
- delivery systems
- urinary tract
- Prior art date
Links
- 208000026723 Urinary tract disease Diseases 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- 230000004064 dysfunction Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 208000014001 urinary system disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261702576P | 2012-09-18 | 2012-09-18 | |
| PCT/US2013/060479 WO2014047221A1 (en) | 2012-09-18 | 2013-09-18 | Drug delivery systems and methods for treatment of bladder voiding dysfunction|and other lower urinary tract disorders by using trospium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL237498A0 IL237498A0 (en) | 2015-04-30 |
| IL237498B true IL237498B (en) | 2018-01-31 |
Family
ID=49301639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL237498A IL237498B (en) | 2012-09-18 | 2015-03-02 | Drug delivery systems and methods for treating bladder emptying dysfunction and other lower urinary tract disorders using tropesium |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10500200B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2897616A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6600256B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102141433B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN111450093A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2013318146B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112015005351A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2883855C (cg-RX-API-DMAC7.html) |
| IL (1) | IL237498B (cg-RX-API-DMAC7.html) |
| MX (2) | MX379066B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2670749C9 (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201502104YA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014047221A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| LT2890384T (lt) | 2012-08-31 | 2022-01-10 | Taris Biomedical Llc | Vaistų pateikimo sistemos ir kraujo vėžio gydymo būdai, apimantys oksaliplatiną |
| CA2882575C (en) | 2012-08-31 | 2020-05-26 | Dennis GIESING | Drug delivery systems and methods for treatment of prostate |
| KR102141433B1 (ko) * | 2012-09-18 | 2020-08-05 | 타리스 바이오메디컬 엘엘씨 | 트로스피움을 이용함으로써 방광 배뇨 장애 및 다른 하부 요도관 장애의 치료를 위한 약물 전달 시스템과 방법 |
| CN106573133B (zh) * | 2014-08-19 | 2020-03-03 | 加利福尼亚大学董事会 | 用于局部药物递送的植入物及其使用方法 |
| GB201506526D0 (en) | 2015-04-17 | 2015-06-03 | Uropharma Ltd And Synesis Llc | Medicinal composition |
| CN106706832A (zh) * | 2015-08-06 | 2017-05-24 | 舒泰神（北京）生物制药股份有限公司 | 一种测定曲司氯铵含量的方法 |
| SI3432970T1 (sl) * | 2017-02-01 | 2021-11-30 | Taris Biomedical Llc | Naprave za dovajanje zdravila IN VIVO |
| CA3071014A1 (en) | 2017-07-25 | 2019-01-31 | Taris Biomedical Llc | Methods of treating tumor metastasis |
| TWI841554B (zh) | 2018-03-21 | 2024-05-11 | 丹麥商珍美寶股份有限公司 | 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法 |
| SG11202010993VA (en) | 2018-05-07 | 2020-12-30 | Genmab As | Methods of treating cancer with a combination of an anti-pd-1 antibody and an anti-tissue factor antibody-drug conjugate |
| CA3107461A1 (en) | 2018-08-01 | 2020-02-06 | Taris Biomedical Llc | Methods of treating overactive bladder using trospium |
| TWI844571B (zh) | 2018-10-30 | 2024-06-11 | 丹麥商珍美寶股份有限公司 | 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法 |
| CA3138433A1 (en) * | 2019-04-30 | 2020-11-05 | Trigone Pharma Ltd. | Formulations and methods for drug instillation into the bladder and treatment of bladder ailments |
| US11344526B2 (en) | 2020-03-20 | 2022-05-31 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11338119B2 (en) | 2020-03-20 | 2022-05-24 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11173291B2 (en) | 2020-03-20 | 2021-11-16 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| KR102596697B1 (ko) | 2021-05-20 | 2023-11-01 | 김정우 | 바위솔 추출물을 유효성분으로 포함하는 화장품 조성물 및 그 제조 방법 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0856312B1 (de) * | 1996-11-27 | 1998-10-14 | Dr. R. Pfleger Chemische Fabrik GmbH | Verwendung von Trospiumchlorid zur Herstellung eines Arzneimittels zur Behandlung von Blasenkrankheiten |
| EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
| US20060058777A1 (en) * | 2002-12-11 | 2006-03-16 | Pia Norup Nielsen | Urinary catheter device with a pharmaceutically active composition |
| WO2004064789A2 (en) | 2003-01-16 | 2004-08-05 | University Of Rochester | Quaternary antimuscarinic compounds for the treatment of bladder diseases |
| DE602004020337D1 (de) | 2004-08-11 | 2009-05-14 | Boehringer Ingelheim Pharma | Anticholinergika enthaltende Arzneimittel zur Behandlung von Krankheiten der ableitenden Harnwege |
| US20060217405A1 (en) * | 2005-03-17 | 2006-09-28 | Indevus Pharmaceuticals, Inc. | Interstitial cystitis treatment |
| US7390816B2 (en) | 2005-06-21 | 2008-06-24 | Bridge Pharma, Inc. | Methods for treating urinary incontinence in patients suffering from memory disorders |
| JP5265359B2 (ja) | 2005-08-11 | 2013-08-14 | マサチューセッツ インスティテュート オブ テクノロジー | 膀胱内薬物送達デバイスおよび方法 |
| EP1967202A1 (en) | 2007-03-05 | 2008-09-10 | AEterna Zentaris GmbH | Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity |
| EP2231254B9 (en) | 2007-12-11 | 2015-04-08 | Massachusetts Institute of Technology | Implantable drug delivery device |
| BRPI0917135A2 (pt) | 2008-08-09 | 2015-11-10 | Massachusetts Inst Technology | dispositivo médico para extensão e retenção em uma vesícula seminal, duto ejaculatório, próstata ou vaso deferente de um paciente, uso de um elastômero reabsorvível, e, dispositivo de bomba osmótica. |
| WO2010151896A1 (en) | 2009-06-26 | 2010-12-29 | Taris Biomedical, Inc. | Solid drug tablets for implantable drug delivery devices |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| EP2512581B1 (en) | 2009-12-17 | 2021-02-17 | TARIS Biomedical LLC | Implantable device with intravesical tolerability |
| US20110218488A1 (en) | 2010-03-05 | 2011-09-08 | Taris Biomedical, Inc. | Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites |
| JP5945544B2 (ja) | 2010-10-06 | 2016-07-05 | タリス バイオメディカル エルエルシー | 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法 |
| WO2012048104A1 (en) | 2010-10-06 | 2012-04-12 | Taris Biomedical, Inc. | Implantable drug delivery device with bladden retention feature |
| AU2012205654B2 (en) | 2011-01-10 | 2016-09-08 | Allergan, Inc. | Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding |
| US9107816B2 (en) * | 2011-02-04 | 2015-08-18 | Taris Biomedical Llc | Implantable device for controlled dissolution and diffusion of low solubility drug |
| KR102141433B1 (ko) * | 2012-09-18 | 2020-08-05 | 타리스 바이오메디컬 엘엘씨 | 트로스피움을 이용함으로써 방광 배뇨 장애 및 다른 하부 요도관 장애의 치료를 위한 약물 전달 시스템과 방법 |
| BR112015022433B1 (pt) | 2013-03-15 | 2022-06-21 | Taris Biomedical Llc | Dispositivo de liberação de droga intravesical |
-
2013
- 2013-09-18 KR KR1020157008403A patent/KR102141433B1/ko active Active
- 2013-09-18 CA CA2883855A patent/CA2883855C/en active Active
- 2013-09-18 CN CN202010161062.6A patent/CN111450093A/zh active Pending
- 2013-09-18 WO PCT/US2013/060479 patent/WO2014047221A1/en not_active Ceased
- 2013-09-18 SG SG11201502104YA patent/SG11201502104YA/en unknown
- 2013-09-18 CN CN201380046758.2A patent/CN104684556A/zh active Pending
- 2013-09-18 JP JP2015532177A patent/JP6600256B2/ja active Active
- 2013-09-18 EP EP13771696.5A patent/EP2897616A1/en active Pending
- 2013-09-18 RU RU2015112196A patent/RU2670749C9/ru active
- 2013-09-18 BR BR112015005351A patent/BR112015005351A2/pt not_active Application Discontinuation
- 2013-09-18 MX MX2015003110A patent/MX379066B/es unknown
- 2013-09-18 AU AU2013318146A patent/AU2013318146B2/en active Active
-
2015
- 2015-03-02 IL IL237498A patent/IL237498B/en active IP Right Grant
- 2015-03-11 MX MX2020002465A patent/MX2020002465A/es unknown
- 2015-03-16 US US14/658,699 patent/US10500200B2/en active Active
-
2018
- 2018-02-02 JP JP2018017300A patent/JP2018080208A/ja active Pending
-
2019
- 2019-12-06 US US16/706,009 patent/US11850244B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201502104YA (en) | 2015-05-28 |
| IL237498A0 (en) | 2015-04-30 |
| CA2883855A1 (en) | 2014-03-27 |
| AU2013318146B2 (en) | 2018-05-10 |
| WO2014047221A1 (en) | 2014-03-27 |
| WO2014047221A9 (en) | 2015-05-21 |
| EP2897616A1 (en) | 2015-07-29 |
| US20200108057A1 (en) | 2020-04-09 |
| KR102141433B1 (ko) | 2020-08-05 |
| CA2883855C (en) | 2020-09-15 |
| MX2015003110A (es) | 2015-06-05 |
| CN111450093A (zh) | 2020-07-28 |
| MX379066B (es) | 2025-03-04 |
| RU2015112196A (ru) | 2016-11-10 |
| JP2015529688A (ja) | 2015-10-08 |
| US11850244B2 (en) | 2023-12-26 |
| US10500200B2 (en) | 2019-12-10 |
| US20150182516A1 (en) | 2015-07-02 |
| KR20150058271A (ko) | 2015-05-28 |
| RU2670749C2 (ru) | 2018-10-25 |
| JP2018080208A (ja) | 2018-05-24 |
| BR112015005351A2 (pt) | 2017-07-04 |
| JP6600256B2 (ja) | 2019-10-30 |
| AU2013318146A1 (en) | 2015-03-19 |
| MX2020002465A (es) | 2020-07-13 |
| RU2670749C9 (ru) | 2018-12-13 |
| CN104684556A (zh) | 2015-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |