IL231666B - Use of non-subtype b gag proteins for lentiviral packaging - Google Patents
Use of non-subtype b gag proteins for lentiviral packagingInfo
- Publication number
- IL231666B IL231666B IL231666A IL23166614A IL231666B IL 231666 B IL231666 B IL 231666B IL 231666 A IL231666 A IL 231666A IL 23166614 A IL23166614 A IL 23166614A IL 231666 B IL231666 B IL 231666B
- Authority
- IL
- Israel
- Prior art keywords
- subtype
- gag proteins
- lentiviral packaging
- lentiviral
- gag
- Prior art date
Links
- 101710177291 Gag polyprotein Proteins 0.000 title 1
- 101710125418 Major capsid protein Proteins 0.000 title 1
- 238000004806 packaging method and process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material
- C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11306222 | 2011-09-26 | ||
| PCT/IB2012/002363 WO2013046034A2 (en) | 2011-09-26 | 2012-09-25 | Use of non-subtype b gag proteins for lentiviral packaging |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL231666A0 IL231666A0 (en) | 2014-05-28 |
| IL231666B true IL231666B (en) | 2018-03-29 |
Family
ID=47522726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL231666A IL231666B (en) | 2011-09-26 | 2014-03-23 | Use of non-subtype b gag proteins for lentiviral packaging |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9752160B2 (enExample) |
| EP (1) | EP2761011B1 (enExample) |
| JP (3) | JP6495653B2 (enExample) |
| KR (1) | KR101811736B1 (enExample) |
| CN (2) | CN107858375A (enExample) |
| AU (1) | AU2012313960B2 (enExample) |
| BR (1) | BR112014007027A2 (enExample) |
| CA (2) | CA2959867C (enExample) |
| DK (1) | DK2761011T3 (enExample) |
| ES (1) | ES2683820T3 (enExample) |
| IL (1) | IL231666B (enExample) |
| SG (1) | SG11201400987QA (enExample) |
| WO (1) | WO2013046034A2 (enExample) |
| ZA (1) | ZA201401780B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2913854A1 (en) | 2013-06-03 | 2014-12-11 | Theravectys | Lentiviral vectors containing an mhc class i, mhc class ii, or beta-2 microglobulin upstream promoter sequence |
| WO2015063706A1 (en) * | 2013-10-31 | 2015-05-07 | Theravectys | Lentiviral vectors for expression of hiv-1 antigens |
| EP3009144A1 (en) * | 2014-10-15 | 2016-04-20 | Theravectys | Lentiviral vectors for inducing CD4+ and CD8+ immune responses in vaccination of humans |
| WO2016120489A2 (en) * | 2015-02-01 | 2016-08-04 | Theravectys | Lentiviral vectors for expression of mycobacterium tuberculosis antigens |
| US12084674B2 (en) * | 2019-10-07 | 2024-09-10 | University Of Utah Research Foundation | Methods and compositions for a HIV based delivery system |
| US20250319173A1 (en) * | 2021-03-12 | 2025-10-16 | Institut Pasteur | Lentiviral vectors targeting antigens to mhc-ii pathway and inducing protective cd8+ and cd4+ t-cell immunity in a host |
| CN114107393A (zh) | 2021-04-07 | 2022-03-01 | 上海劲威生物科技有限公司 | 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2646606B1 (fr) * | 1989-05-03 | 1994-06-17 | Inst Nat Sante Rech Med | Retrovirus hautement cytopathogenique hiv-ndk. fragment d'adn de ce retrovirus, procede de preparation d'une proteine et/ou enzyme de ce virus et leurs utilisations |
| UA68327C2 (en) * | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| US7262049B2 (en) * | 1999-03-16 | 2007-08-28 | Dana-Farber Cancer Institute, Inc. | Pseudotyped lentiviral vectors and uses thereof |
| EP1610816B1 (en) * | 2003-03-28 | 2013-01-02 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Mva virus expressing modified hiv envelope, gag, and pol genes |
| GB0318704D0 (en) * | 2003-08-08 | 2003-09-10 | Sirus Pharmaceuticals Ltd | Chimaeric vector system |
| CA2539021A1 (en) | 2003-09-15 | 2005-03-31 | Chiron Corporation | Combination approaches for generating immune responses |
| GB0702694D0 (en) * | 2007-02-12 | 2007-03-21 | Ark Therapeutics Ltd | Vectors |
| CN101353667B (zh) * | 2008-08-15 | 2011-06-08 | 中国人民解放军军事医学科学院微生物流行病研究所 | Hiv毒株耐药表型分析细胞模型及其专用假型慢病毒 |
-
2012
- 2012-09-25 WO PCT/IB2012/002363 patent/WO2013046034A2/en not_active Ceased
- 2012-09-25 ES ES12813090.3T patent/ES2683820T3/es active Active
- 2012-09-25 SG SG11201400987QA patent/SG11201400987QA/en unknown
- 2012-09-25 AU AU2012313960A patent/AU2012313960B2/en active Active
- 2012-09-25 JP JP2014531334A patent/JP6495653B2/ja active Active
- 2012-09-25 CA CA2959867A patent/CA2959867C/en active Active
- 2012-09-25 EP EP12813090.3A patent/EP2761011B1/en active Active
- 2012-09-25 DK DK12813090.3T patent/DK2761011T3/en active
- 2012-09-25 US US14/346,961 patent/US9752160B2/en active Active
- 2012-09-25 CN CN201710942647.XA patent/CN107858375A/zh active Pending
- 2012-09-25 CN CN201280046712.6A patent/CN104039968B/zh active Active
- 2012-09-25 BR BR112014007027A patent/BR112014007027A2/pt not_active Application Discontinuation
- 2012-09-25 KR KR1020147009812A patent/KR101811736B1/ko active Active
- 2012-09-25 CA CA2849652A patent/CA2849652C/en active Active
-
2014
- 2014-03-11 ZA ZA2014/01780A patent/ZA201401780B/en unknown
- 2014-03-23 IL IL231666A patent/IL231666B/en active IP Right Grant
-
2016
- 2016-09-12 JP JP2016178074A patent/JP2017018132A/ja active Pending
-
2017
- 2017-08-10 US US15/673,454 patent/US20170362607A1/en not_active Abandoned
-
2018
- 2018-07-19 JP JP2018135840A patent/JP2018183165A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014007027A2 (pt) | 2017-04-11 |
| CA2959867C (en) | 2020-04-28 |
| CN107858375A (zh) | 2018-03-30 |
| KR101811736B1 (ko) | 2017-12-22 |
| JP2017018132A (ja) | 2017-01-26 |
| ES2683820T3 (es) | 2018-09-28 |
| WO2013046034A3 (en) | 2013-05-30 |
| WO2013046034A2 (en) | 2013-04-04 |
| ZA201401780B (en) | 2015-09-30 |
| JP6495653B2 (ja) | 2019-04-03 |
| JP2014530000A (ja) | 2014-11-17 |
| CN104039968A (zh) | 2014-09-10 |
| EP2761011A2 (en) | 2014-08-06 |
| AU2012313960A1 (en) | 2014-04-10 |
| KR20140116053A (ko) | 2014-10-01 |
| US9752160B2 (en) | 2017-09-05 |
| AU2012313960B2 (en) | 2016-05-12 |
| HK1200870A1 (en) | 2015-08-14 |
| JP2018183165A (ja) | 2018-11-22 |
| CA2849652A1 (en) | 2013-04-04 |
| CA2849652C (en) | 2017-11-21 |
| NZ622860A (en) | 2016-05-27 |
| EP2761011B1 (en) | 2018-05-23 |
| CA2959867A1 (en) | 2013-04-04 |
| US20170362607A1 (en) | 2017-12-21 |
| IL231666A0 (en) | 2014-05-28 |
| US20140234908A1 (en) | 2014-08-21 |
| CN104039968B (zh) | 2018-10-26 |
| SG11201400987QA (en) | 2014-07-30 |
| DK2761011T3 (en) | 2018-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |