IL225179A - תרכיבים לשימוש בהפרעות עיניות באמצעות דיפירידמול - Google Patents

תרכיבים לשימוש בהפרעות עיניות באמצעות דיפירידמול

Info

Publication number
IL225179A
IL225179A IL225179A IL22517913A IL225179A IL 225179 A IL225179 A IL 225179A IL 225179 A IL225179 A IL 225179A IL 22517913 A IL22517913 A IL 22517913A IL 225179 A IL225179 A IL 225179A
Authority
IL
Israel
Prior art keywords
eye
dipyridamole
comeal
twice daily
drop
Prior art date
Application number
IL225179A
Other languages
English (en)
Other versions
IL225179A0 (he
Inventor
Rogosnitzky Moshe
Original Assignee
Rogosnitzky Moshe
Remedeye Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rogosnitzky Moshe, Remedeye Inc filed Critical Rogosnitzky Moshe
Priority to IL225179A priority Critical patent/IL225179A/he
Publication of IL225179A0 publication Critical patent/IL225179A0/he
Priority to MYPI2015002196A priority patent/MY182591A/en
Priority to KR1020217001495A priority patent/KR20210010638A/ko
Priority to MX2015012716A priority patent/MX2015012716A/es
Priority to EA201591653A priority patent/EA035966B1/ru
Priority to PCT/IB2014/059645 priority patent/WO2014141079A1/en
Priority to CN201480016302.6A priority patent/CN105188702B/zh
Priority to KR1020157027571A priority patent/KR20150126021A/ko
Priority to EP14764673.1A priority patent/EP2968328A4/en
Priority to SG10201706937UA priority patent/SG10201706937UA/en
Priority to BR112015022084A priority patent/BR112015022084A2/pt
Priority to SG11201507092QA priority patent/SG11201507092QA/en
Priority to AU2014229371A priority patent/AU2014229371B2/en
Priority to CA2905594A priority patent/CA2905594A1/en
Priority to JP2015562486A priority patent/JP6820658B2/ja
Priority to US14/483,181 priority patent/US20150031712A1/en
Priority to CL2015002627A priority patent/CL2015002627A1/es
Publication of IL225179A publication Critical patent/IL225179A/he
Priority to US15/428,709 priority patent/US9901580B2/en
Priority to US15/826,725 priority patent/US10226420B2/en
Priority to US16/236,525 priority patent/US10357453B2/en
Priority to US16/444,025 priority patent/US10973758B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL225179A 2013-03-12 2013-03-12 תרכיבים לשימוש בהפרעות עיניות באמצעות דיפירידמול IL225179A (he)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IL225179A IL225179A (he) 2013-03-12 2013-03-12 תרכיבים לשימוש בהפרעות עיניות באמצעות דיפירידמול
JP2015562486A JP6820658B2 (ja) 2013-03-12 2014-03-11 ジピリダモールを用いる眼疾患の治療において使用するための組成物
BR112015022084A BR112015022084A2 (pt) 2013-03-12 2014-03-11 composições para uso em tratamento de distúrbios oculares com o uso de dipiridamol
AU2014229371A AU2014229371B2 (en) 2013-03-12 2014-03-11 Compositions for use in treating eye disorders using dipyridamole
MX2015012716A MX2015012716A (es) 2013-03-12 2014-03-11 Composiciones para el uso en el tratamiento de trastornos oculares que usan dipiridamol.
EA201591653A EA035966B1 (ru) 2013-03-12 2014-03-11 Применение фармацевтической композиции для местного применения для лечения расстройств лакримальной системы и переднего отрезка глаза
PCT/IB2014/059645 WO2014141079A1 (en) 2013-03-12 2014-03-11 Compositions for use in treating eye disorders using dipyridamole
CN201480016302.6A CN105188702B (zh) 2013-03-12 2014-03-11 使用双嘧达莫的用于治疗眼睛疾病的组合物
KR1020157027571A KR20150126021A (ko) 2013-03-12 2014-03-11 다이피리다몰을 이용하여 눈 장애를 치료하는데 사용하기 위한 조성물
EP14764673.1A EP2968328A4 (en) 2013-03-12 2014-03-11 COMPOSITIONS FOR THE TREATMENT OF EYES DISEASES WITH DIPYRIDAMOL
SG10201706937UA SG10201706937UA (en) 2013-03-12 2014-03-11 Compositions for Use in Treating Eye Disorders Using Dipyridamole
MYPI2015002196A MY182591A (en) 2013-03-12 2014-03-11 Compositions for use in treating eye disorders using dipyridamole
SG11201507092QA SG11201507092QA (en) 2013-03-12 2014-03-11 Compositions for use in treating eye disorders using dipyridamole
KR1020217001495A KR20210010638A (ko) 2013-03-12 2014-03-11 다이피리다몰을 이용하여 눈 장애를 치료하는데 사용하기 위한 조성물
CA2905594A CA2905594A1 (en) 2013-03-12 2014-03-11 Compositions for use in treating eye disorders using dipyridamole
US14/483,181 US20150031712A1 (en) 2013-03-12 2014-09-11 Therapeutic Compositions Containing Dipyridamole and Treatment Packs Including Such Compositions and Methods for Producing Same
CL2015002627A CL2015002627A1 (es) 2013-03-12 2015-09-11 Composiciones para el uso en el tratamiento de trastornos oculares que usan dipiridamol
US15/428,709 US9901580B2 (en) 2013-03-12 2017-02-09 Methods of eye treatment using therapeutic compositions containing dipyridamole
US15/826,725 US10226420B2 (en) 2013-03-12 2017-11-30 Methods of eye treatment using therapeutic compositions containing dipyridamole
US16/236,525 US10357453B2 (en) 2013-03-12 2018-12-30 Methods of eye treatment using therapeutic compositions containing dipyridamole
US16/444,025 US10973758B2 (en) 2013-03-12 2019-06-18 Methods of eye treatment using therapeutic compositions containing dipyridamole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL225179A IL225179A (he) 2013-03-12 2013-03-12 תרכיבים לשימוש בהפרעות עיניות באמצעות דיפירידמול

Publications (2)

Publication Number Publication Date
IL225179A0 IL225179A0 (he) 2013-06-27
IL225179A true IL225179A (he) 2017-01-31

Family

ID=48916407

Family Applications (1)

Application Number Title Priority Date Filing Date
IL225179A IL225179A (he) 2013-03-12 2013-03-12 תרכיבים לשימוש בהפרעות עיניות באמצעות דיפירידמול

Country Status (14)

Country Link
EP (1) EP2968328A4 (he)
JP (1) JP6820658B2 (he)
KR (2) KR20150126021A (he)
CN (1) CN105188702B (he)
AU (1) AU2014229371B2 (he)
BR (1) BR112015022084A2 (he)
CA (1) CA2905594A1 (he)
CL (1) CL2015002627A1 (he)
EA (1) EA035966B1 (he)
IL (1) IL225179A (he)
MX (1) MX2015012716A (he)
MY (1) MY182591A (he)
SG (2) SG10201706937UA (he)
WO (1) WO2014141079A1 (he)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180015090A1 (en) * 2015-01-28 2018-01-18 Realinn Life Science Limited COMPOUNDS FOR ENHANCING PPARy EXPRESSION AND NUCLEAR TRANSLOCATION AND THERAPEUTIC USE THEREOF
US20180092776A1 (en) 2016-09-30 2018-04-05 Sara Heikali Method and device for treating and managing diseased ocular tissue
WO2021001805A1 (en) 2019-07-04 2021-01-07 Ocular Discovery Ltd. Stable dipyridamole formulations and their methods of preparation
WO2021001806A1 (en) 2019-07-04 2021-01-07 Ocular Discovery Ltd. Stable dipyridamole formulations with reduced impurities

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07258084A (ja) * 1994-03-17 1995-10-09 Rohto Pharmaceut Co Ltd ジピリダモールを必須成分とする眼圧降下剤
US5780450A (en) * 1995-11-21 1998-07-14 Alcon Laboratories, Inc. Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage
US20060104968A1 (en) * 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
BRPI0618643A2 (pt) * 2005-11-09 2011-09-06 Combinatorx Inc composição compreendendo um par de fármacos, composição compreendendo um corticosteróide e um imunossupressor dependente de imunofilina não-esteróide, kits e uso
WO2010056710A1 (en) * 2008-11-11 2010-05-20 Biovista, Inc. Compositions and methods for treating eye diseases
EP2363126A1 (en) * 2010-03-04 2011-09-07 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Composition comprising as active ingredient L-carnitine in combination with hydroxykynurenine-O-beta-DL-glucoside, for the prevention and/or treatment of pathologies of the eye due to ultraviolet radiation

Also Published As

Publication number Publication date
JP2016514123A (ja) 2016-05-19
EA201591653A1 (ru) 2017-05-31
AU2014229371A1 (en) 2015-10-29
AU2014229371B2 (en) 2018-05-10
EP2968328A1 (en) 2016-01-20
WO2014141079A1 (en) 2014-09-18
CN105188702A (zh) 2015-12-23
MY182591A (en) 2021-01-26
KR20210010638A (ko) 2021-01-27
MX2015012716A (es) 2016-07-06
EP2968328A4 (en) 2016-11-23
EA035966B1 (ru) 2020-09-07
CN105188702B (zh) 2019-03-26
CL2015002627A1 (es) 2016-03-11
BR112015022084A2 (pt) 2017-07-18
SG10201706937UA (en) 2017-09-28
JP6820658B2 (ja) 2021-01-27
SG11201507092QA (en) 2015-10-29
CA2905594A1 (en) 2014-09-18
KR20150126021A (ko) 2015-11-10
IL225179A0 (he) 2013-06-27

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