IL212858A - Fibroblastic growth factor-9 to encourage hair follicle rejuvenation after skin injury - Google Patents

Fibroblastic growth factor-9 to encourage hair follicle rejuvenation after skin injury

Info

Publication number
IL212858A
IL212858A IL212858A IL21285811A IL212858A IL 212858 A IL212858 A IL 212858A IL 212858 A IL212858 A IL 212858A IL 21285811 A IL21285811 A IL 21285811A IL 212858 A IL212858 A IL 212858A
Authority
IL
Israel
Prior art keywords
polypeptide
growth factor
fibroblast growth
hair follicle
promoting hair
Prior art date
Application number
IL212858A
Other languages
English (en)
Hebrew (he)
Other versions
IL212858A0 (en
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of IL212858A0 publication Critical patent/IL212858A0/en
Publication of IL212858A publication Critical patent/IL212858A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
IL212858A 2008-11-12 2011-05-12 Fibroblastic growth factor-9 to encourage hair follicle rejuvenation after skin injury IL212858A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11402808P 2008-11-12 2008-11-12
PCT/US2009/064049 WO2010056759A1 (en) 2008-11-12 2009-11-11 Fibroblast growth factor-9 promotes hair follicle regeneration after wounding

Publications (2)

Publication Number Publication Date
IL212858A0 IL212858A0 (en) 2011-07-31
IL212858A true IL212858A (en) 2016-12-29

Family

ID=42170304

Family Applications (2)

Application Number Title Priority Date Filing Date
IL212858A IL212858A (en) 2008-11-12 2011-05-12 Fibroblastic growth factor-9 to encourage hair follicle rejuvenation after skin injury
IL249309A IL249309A0 (en) 2008-11-12 2016-11-30 Fibroblastic growth factor-9 to encourage regeneration of hair follicles after skin injury

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL249309A IL249309A0 (en) 2008-11-12 2016-11-30 Fibroblastic growth factor-9 to encourage regeneration of hair follicles after skin injury

Country Status (9)

Country Link
US (4) US8871711B2 (enExample)
EP (2) EP2361119B1 (enExample)
JP (1) JP5723780B2 (enExample)
KR (2) KR20170024148A (enExample)
AU (2) AU2009314147B2 (enExample)
BR (1) BRPI0915262B1 (enExample)
CA (1) CA2743610C (enExample)
IL (2) IL212858A (enExample)
WO (1) WO2010056759A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008537940A (ja) 2005-03-29 2008-10-02 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア 新しい毛包の形成、はげ頭症の治療、及び除毛をするための方法
WO2010056759A1 (en) 2008-11-12 2010-05-20 The Trustees Of The University Of Pennsylvania Fibroblast growth factor-9 promotes hair follicle regeneration after wounding
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
ES2670719T3 (es) 2010-08-27 2018-05-31 Sienna Biopharmaceuticals, Inc. Composiciones y métodos para la termomodulación dirigida
GB2485475A (en) * 2010-11-10 2012-05-16 Pangaea Lab Ltd Topical growth factor application using controlled and multiple wounding of the skin
EP3178465A1 (en) 2010-12-06 2017-06-14 Follica, Inc. Methods for treating baldness and promoting hair growth
EP3272388A1 (en) 2012-10-11 2018-01-24 Nanocomposix, Inc. Silver nanoplate compositions and methods
EP2735303A1 (en) * 2012-11-23 2014-05-28 Pilosciences Hair growth compositions and methods
KR101578901B1 (ko) 2013-09-11 2015-12-28 (주)셀아이콘랩 발모 촉진 펩타이드, 이의 제조방법, 및, 이를 함유하는 탈모방지 또는 발모촉진용 조성물
WO2015164800A2 (en) * 2014-04-24 2015-10-29 University Of Central Florida Research Foundation, Inc. Compositions and methods for modulating polarization of monocytes
KR101841482B1 (ko) * 2016-02-25 2018-03-23 (주)피앤피바이오팜 안정성이 증가된 인간 섬유아세포 성장인자-9 변이체 및 이의 용도
KR102535575B1 (ko) * 2016-02-26 2023-05-23 (주)피앤피바이오팜 고안정성 섬유아세포 성장인자-9 변이체를 유효성분으로 포함하는 헤어케어 화장품 조성물
WO2019099850A1 (en) * 2017-11-16 2019-05-23 Aivita Biomedical, Inc. Use of cell membrane-bound signaling factors
CN110551692B (zh) * 2019-07-09 2021-06-25 吕贯廷 hFGF9基因修饰型间充质干细胞及其制备方法和用途
WO2021232055A1 (en) * 2020-05-12 2021-11-18 Chemistryrx Methods for treating hair loss and compositions for same
CA3207296A1 (en) * 2021-01-06 2022-07-14 The Penn State Research Foundation Methods and materials for treating hair loss
EP4284335A1 (en) 2021-02-01 2023-12-06 RegenxBio Inc. Gene therapy for neuronal ceroid lipofuscinoses
US12268677B2 (en) 2022-04-27 2025-04-08 The Penn State Research Foundation 4-aminopyridine (4-AP) and bone morphogenetic protein 2 (BMP-2)
AU2024255051A1 (en) * 2023-04-12 2025-08-07 Estetra Srl Topical compositions for promoting hair growth
CN118286487B (zh) * 2024-04-01 2024-09-17 吉林农业大学 一种促进复杂感染伤口愈合的多功能纳米纤维膜的制备方法
CN118161418B (zh) * 2024-05-14 2024-07-23 美归(成都)生物材料合伙企业(有限合伙) 保湿美白脂质体精华液及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04224522A (ja) 1990-04-27 1992-08-13 Merck & Co Inc 繊維芽細胞増殖因子含有組成物による禿頭症の治療又は予防方法
JPH10279501A (ja) 1997-02-10 1998-10-20 Rohto Pharmaceut Co Ltd 育毛剤
US20070009544A1 (en) * 1999-06-17 2007-01-11 Ronit Eisenberg Anti-allergic complex molecules
WO2001074164A1 (en) * 2000-03-31 2001-10-11 The General Hospital Corporation Methods of modulating hair growth
US7588937B2 (en) * 2001-10-03 2009-09-15 Wisconsin Alumni Research Foundation Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells
JP2003192541A (ja) * 2001-12-26 2003-07-09 Pola Chem Ind Inc 育毛促進剤及び育毛用の皮膚外用剤
JPWO2005044205A1 (ja) 2003-11-11 2007-05-17 株式会社資生堂 毛髪の太毛化の方法及び組成物
JP2008537940A (ja) * 2005-03-29 2008-10-02 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア 新しい毛包の形成、はげ頭症の治療、及び除毛をするための方法
WO2010056759A1 (en) * 2008-11-12 2010-05-20 The Trustees Of The University Of Pennsylvania Fibroblast growth factor-9 promotes hair follicle regeneration after wounding
US20070092496A1 (en) * 2005-10-17 2007-04-26 Aderans Research Institute, Inc. Method of delivering cells to the skin
US20070122387A1 (en) 2005-11-22 2007-05-31 Aderans Research Institute, Inc. Hair grafts derived from plucked hair
US7714014B2 (en) * 2005-12-09 2010-05-11 The Regents Of The University Of California Targeting GLI proteins in human cancer by small molecules
WO2007070983A1 (en) 2005-12-22 2007-06-28 Apollo Life Sciences Limited Transdermal delivery of pharmaceutical agents
EP1986731A4 (en) 2006-02-09 2012-11-07 Aderans Res Inst Inc APPARATUS AND METHODS FOR DELIVERING FLUID AND MATERIAL TO A SUBJECT
US8273747B2 (en) 2006-11-02 2012-09-25 Curis, Inc. Small organic molecule regulators of cell proliferation

Also Published As

Publication number Publication date
AU2009314147B2 (en) 2015-12-24
WO2010056759A1 (en) 2010-05-20
EP3144034A1 (en) 2017-03-22
CA2743610C (en) 2021-04-27
AU2009314147A1 (en) 2010-05-20
CA2743610A1 (en) 2010-05-20
EP2361119A1 (en) 2011-08-31
IL249309A0 (en) 2017-01-31
JP5723780B2 (ja) 2015-05-27
KR20110092301A (ko) 2011-08-17
KR20170024148A (ko) 2017-03-06
BRPI0915262B1 (pt) 2018-06-05
EP2361119A4 (en) 2014-01-08
IL212858A0 (en) 2011-07-31
US20180280475A1 (en) 2018-10-04
US8871711B2 (en) 2014-10-28
JP2012508750A (ja) 2012-04-12
EP2361119B1 (en) 2018-09-19
US20150216934A1 (en) 2015-08-06
AU2016201796A1 (en) 2016-05-05
BRPI0915262A2 (pt) 2016-02-16
US20110282267A1 (en) 2011-11-17
KR101711995B1 (ko) 2017-03-06
US20200197488A1 (en) 2020-06-25

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