IL205720A - Use of non-organic nitrite and its salts to catalyze blood vessels in chronic ischemia - Google Patents
Use of non-organic nitrite and its salts to catalyze blood vessels in chronic ischemiaInfo
- Publication number
- IL205720A IL205720A IL205720A IL20572010A IL205720A IL 205720 A IL205720 A IL 205720A IL 205720 A IL205720 A IL 205720A IL 20572010 A IL20572010 A IL 20572010A IL 205720 A IL205720 A IL 205720A
- Authority
- IL
- Israel
- Prior art keywords
- salts
- blood vessel
- vessel growth
- tissue ischemia
- inorganic nitrite
- Prior art date
Links
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 title 1
- 210000004204 blood vessel Anatomy 0.000 title 1
- 230000001684 chronic effect Effects 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 208000028867 ischemia Diseases 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US315007P | 2007-11-15 | 2007-11-15 | |
| PCT/US2008/083830 WO2009065142A2 (en) | 2007-11-15 | 2008-11-17 | Use of nitrite salts in chronic ischemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL205720A0 IL205720A0 (en) | 2010-11-30 |
| IL205720A true IL205720A (en) | 2015-08-31 |
Family
ID=40639493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL205720A IL205720A (en) | 2007-11-15 | 2010-05-12 | Use of non-organic nitrite and its salts to catalyze blood vessels in chronic ischemia |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9649334B2 (OSRAM) |
| EP (1) | EP2219657A4 (OSRAM) |
| JP (2) | JP5795165B2 (OSRAM) |
| CN (1) | CN101939014B (OSRAM) |
| AU (1) | AU2008322437B2 (OSRAM) |
| IL (1) | IL205720A (OSRAM) |
| WO (1) | WO2009065142A2 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9649334B2 (en) | 2007-11-15 | 2017-05-16 | The Uab Research Foundation | Use of nitrite salts in chronic ischemia |
| US8568793B2 (en) | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| WO2010147742A2 (en) | 2009-06-18 | 2010-12-23 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| US20130209584A1 (en) * | 2009-10-14 | 2013-08-15 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| US10463689B2 (en) | 2009-10-14 | 2019-11-05 | Board Of Supervisors Of Louisiana State University | Pharmaceutical formulations of nitrite and uses thereof |
| WO2014130691A2 (en) * | 2013-02-20 | 2014-08-28 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| US10517817B2 (en) | 2013-05-09 | 2019-12-31 | Syk Technologies, Llc | Deep topical systemic nitric oxide therapy apparatus and method |
| WO2017132275A1 (en) | 2016-01-27 | 2017-08-03 | Syk Technologies, Llc | Nitric oxide topical application apparatus and methods |
| JP7333919B2 (ja) | 2017-09-05 | 2023-08-28 | エクセル メッド、エルエルシー | 虚血を治療するためのヘパリン組成物 |
| PH12021551384A1 (en) | 2019-01-02 | 2022-03-28 | Celagenex Res India Pvt Ltd | Synergistic nutritional compositions for pain management |
| US12459820B2 (en) | 2020-06-11 | 2025-11-04 | J. W. Randolph Miller | Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914446A (en) | 1958-06-26 | 1959-11-24 | Upjohn Co | Nitrite stabilized ascorbic acid-cyanocobalamin compositions |
| US4650484A (en) | 1983-02-03 | 1987-03-17 | Alza Corporation | Method for treating ischemic conditions |
| IE64726B1 (en) | 1987-11-20 | 1995-08-23 | Elan Corp Plc | Pharmaceutical formulations for preventing drug tolerance |
| US5122384A (en) | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
| US5278192A (en) | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
| US6709681B2 (en) | 1995-02-17 | 2004-03-23 | Aberdeen University | Acidified nitrite as an antimicrobial agent |
| US20110196039A9 (en) | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
| US5648101A (en) * | 1994-11-14 | 1997-07-15 | Tawashi; Rashad | Drug delivery of nitric oxide |
| US5770645A (en) | 1996-08-02 | 1998-06-23 | Duke University Medical Center | Polymers for delivering nitric oxide in vivo |
| US5994444A (en) | 1997-10-16 | 1999-11-30 | Medtronic, Inc. | Polymeric material that releases nitric oxide |
| US7371415B1 (en) | 1998-04-03 | 2008-05-13 | The Daily Wellness Company | Method and composition for improving sexual fitness |
| US7015876B1 (en) | 1998-06-03 | 2006-03-21 | Lear Corporation | Heads-up display with improved contrast |
| US6103275A (en) * | 1998-06-10 | 2000-08-15 | Nitric Oxide Solutions | Systems and methods for topical treatment with nitric oxide |
| WO2000003725A1 (en) | 1998-07-14 | 2000-01-27 | Paracelsian, Inc. | Method for identifying and confirming consistent bio-functionality of natural compositions |
| DK1146862T3 (da) | 1999-01-29 | 2003-07-21 | Disphar Int Bv | Farmaceutiske sammensætninger |
| GB9905425D0 (en) | 1999-03-09 | 1999-05-05 | Queen Mary & Westfield College | Pharmaceutical composition |
| US6314956B1 (en) | 1999-09-08 | 2001-11-13 | Duke University | Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders |
| CN1299690C (zh) * | 2000-07-28 | 2007-02-14 | 生物能量公司 | 用于提高心血管功能的组合物 |
| GB0119011D0 (en) | 2001-08-03 | 2001-09-26 | Univ Aberdeen | Treatment of nail infections |
| AU2002357935A1 (en) | 2001-12-18 | 2003-06-30 | Alza Corporation | Dosage form for providing time-varying patterns of drug delivery |
| EP1336602A1 (en) | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
| CA2379211A1 (fr) | 2002-03-28 | 2003-09-28 | Institut De Cardiologie De Montreal | Utilisation du bleu de methylene pour renverser la reaction hemodynamique exageree induite par la combinaison d'un derive nitre et du sildenafil ou d'une molecule de meme classe (inhibiteur de la phosphodiesterase) |
| AU2004257693B8 (en) * | 2003-07-09 | 2009-08-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of nitrite salts for the treatment of cardiovascular conditions |
| WO2005018561A2 (en) | 2003-08-20 | 2005-03-03 | Nitromed, Inc. | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use |
| WO2005023189A2 (en) * | 2003-09-03 | 2005-03-17 | Pharmacia Corporation | Method of cox-2 selective inhibitor and nitric oxide-donating agent |
| US7362274B1 (en) * | 2004-07-09 | 2008-04-22 | Huan-Cheng Lien | Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna |
| US20060083824A1 (en) | 2004-10-20 | 2006-04-20 | Pbm Products Llc | Nutritional supplements for glucose intolerant individuals |
| BRPI0610180A2 (pt) | 2005-05-24 | 2012-09-25 | Wellgen Inc | métodos para prevenir, para tratar, e para tratar ou controlar uma condição associada à inflamação |
| NZ594596A (en) | 2006-02-10 | 2011-10-28 | Mannatech Inc | All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization |
| GB0607402D0 (en) | 2006-04-12 | 2006-05-24 | Barts & London Nhs Trust | Therapeutic composition and use |
| WO2007149520A2 (en) * | 2006-06-21 | 2007-12-27 | Albert Einstein College Of Medicine Of Yeshiva University | Compositions for sustained release of nitric oxide, methods of preparing same and uses thereof |
| EP3159000B1 (en) | 2007-02-26 | 2025-05-21 | HeartBeet Ltd. | Performance enhancing composition |
| CA3187624A1 (en) | 2007-02-26 | 2008-09-04 | Heartbeet Ltd. | New use of nitrites and nitrates and compositions containing these |
| WO2008153762A2 (en) | 2007-05-25 | 2008-12-18 | N30 Pharmaceuticals, Llc | S-nitrosothiol formulations and storage systems |
| US9649334B2 (en) | 2007-11-15 | 2017-05-16 | The Uab Research Foundation | Use of nitrite salts in chronic ischemia |
| AU2008345034A1 (en) | 2007-12-27 | 2009-07-09 | Aires Pharmaceuticals, Inc. | Aerosolized nitrite and nitric oxide - donating compounds and uses thereof |
| WO2010036236A1 (en) | 2008-09-23 | 2010-04-01 | Baker Hughes Incorporated | Anchor assembly |
| US8568793B2 (en) | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| WO2010147742A2 (en) | 2009-06-18 | 2010-12-23 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| US20130209584A1 (en) | 2009-10-14 | 2013-08-15 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| US10463689B2 (en) | 2009-10-14 | 2019-11-05 | Board Of Supervisors Of Louisiana State University | Pharmaceutical formulations of nitrite and uses thereof |
| US20140127329A1 (en) | 2011-03-31 | 2014-05-08 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Use of nitrites for the treatment of cerebral amyloid angiopathy, age associated dementia, and cognitive decline |
| WO2012142413A2 (en) | 2011-04-14 | 2012-10-18 | Theravasc Inc. | Nitrite compositions and uses thereof |
| US9294956B2 (en) | 2011-12-29 | 2016-03-22 | Qualcomm Incorporated | Application-server-assisted preemptive multicast bearer establishment for real-time low-latency applications |
| WO2014130691A2 (en) * | 2013-02-20 | 2014-08-28 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
-
2008
- 2008-11-17 US US12/741,436 patent/US9649334B2/en active Active
- 2008-11-17 CN CN200880116483.4A patent/CN101939014B/zh not_active Expired - Fee Related
- 2008-11-17 EP EP08849380.4A patent/EP2219657A4/en not_active Withdrawn
- 2008-11-17 AU AU2008322437A patent/AU2008322437B2/en not_active Ceased
- 2008-11-17 JP JP2010534267A patent/JP5795165B2/ja active Active
- 2008-11-17 WO PCT/US2008/083830 patent/WO2009065142A2/en not_active Ceased
-
2010
- 2010-05-12 IL IL205720A patent/IL205720A/en active IP Right Grant
-
2014
- 2014-05-08 JP JP2014097072A patent/JP5908527B2/ja not_active Expired - Fee Related
-
2017
- 2017-04-10 US US15/483,187 patent/US10864229B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008322437B2 (en) | 2013-11-07 |
| JP2014139255A (ja) | 2014-07-31 |
| EP2219657A2 (en) | 2010-08-25 |
| US10864229B2 (en) | 2020-12-15 |
| JP2011503212A (ja) | 2011-01-27 |
| US9649334B2 (en) | 2017-05-16 |
| JP5795165B2 (ja) | 2015-10-14 |
| WO2009065142A2 (en) | 2009-05-22 |
| CN101939014A (zh) | 2011-01-05 |
| US20110311653A1 (en) | 2011-12-22 |
| JP5908527B2 (ja) | 2016-04-26 |
| CN101939014B (zh) | 2016-04-27 |
| AU2008322437A1 (en) | 2009-05-22 |
| IL205720A0 (en) | 2010-11-30 |
| EP2219657A4 (en) | 2020-01-08 |
| US20170312310A1 (en) | 2017-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |