IL201476A - Factor D Antagonist Antibody for Use in the Prevention and Treatment of Ophthalmic-Related Ocular Diseases - Google Patents

Factor D Antagonist Antibody for Use in the Prevention and Treatment of Ophthalmic-Related Ocular Diseases

Info

Publication number
IL201476A
IL201476A IL201476A IL20147609A IL201476A IL 201476 A IL201476 A IL 201476A IL 201476 A IL201476 A IL 201476A IL 20147609 A IL20147609 A IL 20147609A IL 201476 A IL201476 A IL 201476A
Authority
IL
Israel
Prior art keywords
complement
antibodies
prevention
factor
treatment
Prior art date
Application number
IL201476A
Other languages
English (en)
Hebrew (he)
Other versions
IL201476A0 (en
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39638868&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL201476(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL201476A0 publication Critical patent/IL201476A0/en
Publication of IL201476A publication Critical patent/IL201476A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
IL201476A 2007-05-23 2009-10-13 Factor D Antagonist Antibody for Use in the Prevention and Treatment of Ophthalmic-Related Ocular Diseases IL201476A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93979107P 2007-05-23 2007-05-23
PCT/US2008/064526 WO2008147883A1 (en) 2007-05-23 2008-05-22 Prevention and treatment of complement-associated eye conditions

Publications (2)

Publication Number Publication Date
IL201476A0 IL201476A0 (en) 2010-05-31
IL201476A true IL201476A (en) 2016-11-30

Family

ID=39638868

Family Applications (2)

Application Number Title Priority Date Filing Date
IL201476A IL201476A (en) 2007-05-23 2009-10-13 Factor D Antagonist Antibody for Use in the Prevention and Treatment of Ophthalmic-Related Ocular Diseases
IL248552A IL248552A0 (en) 2007-05-23 2016-10-27 Prevention and treatment of related eye conditions - complementary

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL248552A IL248552A0 (en) 2007-05-23 2016-10-27 Prevention and treatment of related eye conditions - complementary

Country Status (28)

Country Link
US (6) US8007791B2 (cg-RX-API-DMAC7.html)
EP (1) EP2152755B1 (cg-RX-API-DMAC7.html)
JP (4) JP5416695B2 (cg-RX-API-DMAC7.html)
KR (1) KR101540126B1 (cg-RX-API-DMAC7.html)
CN (3) CN107096029B (cg-RX-API-DMAC7.html)
AR (1) AR066660A1 (cg-RX-API-DMAC7.html)
AU (1) AU2008256835B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0811142A8 (cg-RX-API-DMAC7.html)
CA (1) CA2683498A1 (cg-RX-API-DMAC7.html)
CL (1) CL2008001498A1 (cg-RX-API-DMAC7.html)
CY (1) CY1116062T1 (cg-RX-API-DMAC7.html)
DK (1) DK2152755T3 (cg-RX-API-DMAC7.html)
ES (1) ES2533242T3 (cg-RX-API-DMAC7.html)
HK (1) HK1207327A1 (cg-RX-API-DMAC7.html)
HR (1) HRP20150281T1 (cg-RX-API-DMAC7.html)
IL (2) IL201476A (cg-RX-API-DMAC7.html)
MX (1) MX2009012422A (cg-RX-API-DMAC7.html)
PE (1) PE20090294A1 (cg-RX-API-DMAC7.html)
PH (1) PH12013500992B1 (cg-RX-API-DMAC7.html)
PL (1) PL2152755T3 (cg-RX-API-DMAC7.html)
PT (1) PT2152755E (cg-RX-API-DMAC7.html)
RS (1) RS53901B1 (cg-RX-API-DMAC7.html)
RU (2) RU2522976C2 (cg-RX-API-DMAC7.html)
SG (1) SG10201401404RA (cg-RX-API-DMAC7.html)
SI (1) SI2152755T1 (cg-RX-API-DMAC7.html)
TW (2) TW201417829A (cg-RX-API-DMAC7.html)
WO (1) WO2008147883A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200907028B (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
US20160272726A1 (en) 2016-09-22
KR20100033973A (ko) 2010-03-31
MX2009012422A (es) 2009-12-04
TW201417829A (zh) 2014-05-16
EP2152755A1 (en) 2010-02-17
CN101754980B (zh) 2014-10-29
SG10201401404RA (en) 2014-08-28
US20130302333A1 (en) 2013-11-14
AU2008256835A1 (en) 2008-12-04
JP2014087346A (ja) 2014-05-15
PL2152755T3 (pl) 2015-06-30
TWI419704B (zh) 2013-12-21
PH12013500992A1 (en) 2016-01-25
PT2152755E (pt) 2015-04-01
KR101540126B1 (ko) 2015-07-28
US8268310B2 (en) 2012-09-18
CN101754980A (zh) 2010-06-23
EP2152755B1 (en) 2014-12-31
CL2008001498A1 (es) 2009-06-12
JP2017197577A (ja) 2017-11-02
US8007791B2 (en) 2011-08-30
CN107096029A (zh) 2017-08-29
US8497094B2 (en) 2013-07-30
IL201476A0 (en) 2010-05-31
RU2009147744A (ru) 2011-06-27
PE20090294A1 (es) 2009-03-27
AR066660A1 (es) 2009-09-02
JP2010528047A (ja) 2010-08-19
CY1116062T1 (el) 2017-02-08
US20180079826A1 (en) 2018-03-22
RS53901B1 (sr) 2015-08-31
TW200904471A (en) 2009-02-01
DK2152755T3 (en) 2015-03-02
ES2533242T3 (es) 2015-04-08
HK1207327A1 (en) 2016-01-29
CA2683498A1 (en) 2008-12-04
BRPI0811142A8 (pt) 2018-12-18
HRP20150281T1 (hr) 2015-04-10
CN107096029B (zh) 2021-02-26
CN104367999A (zh) 2015-02-25
HK1139161A1 (en) 2010-09-10
US20130052685A1 (en) 2013-02-28
IL248552A0 (en) 2016-12-29
RU2014113046A (ru) 2015-10-10
RU2522976C2 (ru) 2014-07-20
WO2008147883A8 (en) 2013-05-23
US20090181017A1 (en) 2009-07-16
ZA200907028B (en) 2010-12-29
JP2016145205A (ja) 2016-08-12
JP5416695B2 (ja) 2014-02-12
WO2008147883A1 (en) 2008-12-04
US20110282034A1 (en) 2011-11-17
PH12013500992B1 (en) 2018-12-14
SI2152755T1 (sl) 2015-05-29
AU2008256835B2 (en) 2013-08-01
BRPI0811142A2 (pt) 2014-12-23

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