LTPA2021506I1 - Anti-P-selektino antikūnai ir jų naudojimo būdai uždegiminių ligų gydymui - Google Patents

Anti-P-selektino antikūnai ir jų naudojimo būdai uždegiminių ligų gydymui

Info

Publication number
LTPA2021506I1
LTPA2021506I1 LTPA2021506C LTPA2021506C LTPA2021506I1 LT PA2021506 I1 LTPA2021506 I1 LT PA2021506I1 LT PA2021506 C LTPA2021506 C LT PA2021506C LT PA2021506 C LTPA2021506 C LT PA2021506C LT PA2021506 I1 LTPA2021506 I1 LT PA2021506I1
Authority
LT
Lithuania
Prior art keywords
treatment
inflammatory diseases
selectin antibodies
selectin
antibodies
Prior art date
Application number
LTPA2021506C
Other languages
English (en)
Original Assignee
Novartis Ag
Oklahoma Medical Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Oklahoma Medical Research Foundation filed Critical Novartis Ag
Publication of LTPA2021506I1 publication Critical patent/LTPA2021506I1/lt
Publication of LTC2662091I2 publication Critical patent/LTC2662091I2/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTPA2021506C 2006-12-01 2021-04-13 Anti-p-selektino antikūnai ir jų naudojimo būdai uždegiminių ligų gydymui LTC2662091I2 (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87217006P 2006-12-01 2006-12-01
EP07867601A EP2097105A4 (en) 2006-12-01 2007-11-30 ANTI-P-SELECTINE ANTIBODIES AND METHODS FOR USE IN THE TREATMENT OF INFLAMMATORY DISEASES
PCT/US2007/024692 WO2008069999A2 (en) 2006-12-01 2007-11-30 Anti-p-selectin antibodies and methods of using the same to treat inflammatory diseases

Publications (2)

Publication Number Publication Date
LTPA2021506I1 true LTPA2021506I1 (lt) 2021-05-10
LTC2662091I2 LTC2662091I2 (lt) 2022-10-10

Family

ID=39492818

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP13164403.1T LT2662091T (lt) 2006-12-01 2007-11-30 Anti-p-selektino antikūnai ir jų naudojimo būdai uždegiminių ligų gydymui
LTPA2021506C LTC2662091I2 (lt) 2006-12-01 2021-04-13 Anti-p-selektino antikūnai ir jų naudojimo būdai uždegiminių ligų gydymui

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP13164403.1T LT2662091T (lt) 2006-12-01 2007-11-30 Anti-p-selektino antikūnai ir jų naudojimo būdai uždegiminių ligų gydymui

Country Status (11)

Country Link
US (2) US8377440B2 (lt)
EP (3) EP3501538A1 (lt)
CY (1) CY1121072T1 (lt)
DK (1) DK2662091T3 (lt)
ES (1) ES2699273T3 (lt)
HU (3) HUE041957T2 (lt)
LT (2) LT2662091T (lt)
PL (1) PL2662091T3 (lt)
PT (1) PT2662091T (lt)
SI (1) SI2662091T1 (lt)
WO (1) WO2008069999A2 (lt)

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EP3501538A1 (en) 2006-12-01 2019-06-26 Novartis AG Anti-p-selectin antibodies and methods of using the same to treat inflammatory diseases
PL2654781T3 (pl) * 2010-12-21 2018-09-28 Novartis Ag Przeciwciała anty-p-selektynowe i sposoby ich zastosowania i identyfikacji
US10307487B2 (en) 2013-07-09 2019-06-04 President And Fellows Of Harvard College Microvessel endothelial cell surface markers and uses thereof
US10206941B2 (en) 2013-07-09 2019-02-19 President And Fellows Of Harvard College Venule endothelial cell genes and uses thereof
JOP20190101A1 (ar) * 2016-11-03 2019-05-05 Novartis Ag أنظمة علاج
TW201839136A (zh) 2017-02-06 2018-11-01 瑞士商諾華公司 治療血色素異常症之組合物及方法
EP3595645A1 (en) 2017-03-15 2020-01-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Pharmaceutical compositions for the treatment of thrombosis in patients suffering from a myeloproliferative neoplasm
BR112019023540A2 (pt) * 2017-05-10 2020-05-26 The Wistar Institute Of Anatomy And Biology Método para gerar uma sequência de ácidos nucleicos e para tratar um sujeito, anticorpo codificado por dna estruturalmente modificado, e, composição.
WO2018234308A1 (en) 2017-06-20 2018-12-27 INSERM (Institut National de la Santé et de la Recherche Médicale) METHODS FOR IDENTIFYING IF PATIENTS WITH ACUTE CARDIAC DISEASE FAILURE (ICAD) HAVE A HYPERCOAGULABLE CONDITION
CN107299112A (zh) * 2017-06-22 2017-10-27 广东药科大学 一种炎症分子(psgl‑1)缺失的脂代谢异常模型的构建及其应用
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US20210002374A1 (en) 2018-03-08 2021-01-07 Novartis Ag USE OF an anti-P-selectin antibody
AU2020289364A1 (en) 2019-06-07 2022-01-06 Novartis Ag Use of an anti-P-selectin antibody
EP3790545A4 (en) 2019-07-17 2021-07-28 Emmaus Medical, Inc. METHODS AND COMPOSITIONS FOR TREATMENT OF SICKLE CLEANEMIA AND THALASSEMIA
BR112022008097A2 (pt) 2019-10-30 2022-08-02 Novartis Ag Formulação de anticorpo que contém crizanlizumabe
US20230020548A1 (en) 2019-12-09 2023-01-19 Novartis Ag Anti-interleukin 1 beta antibodies for treatment of sickle cell disease
CN115176005A (zh) 2019-12-18 2022-10-11 诺华股份有限公司 用于治疗血红蛋白病的组合物和方法
WO2022269518A2 (en) 2021-06-23 2022-12-29 Novartis Ag Compositions and methods for the treatment of hemoglobinopathies

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Also Published As

Publication number Publication date
EP2662091A2 (en) 2013-11-13
HUE041957T2 (hu) 2019-06-28
ES2699273T3 (es) 2019-02-08
SI2662091T1 (sl) 2019-01-31
PL2662091T3 (pl) 2019-05-31
HUS2100011I1 (hu) 2021-05-28
EP2662091B1 (en) 2018-08-22
US8377440B2 (en) 2013-02-19
CY1121072T1 (el) 2019-12-11
LTC2662091I2 (lt) 2022-10-10
US20140072551A1 (en) 2014-03-13
US20110243926A1 (en) 2011-10-06
DK2662091T3 (en) 2018-12-17
HUS2100015I1 (hu) 2021-05-28
EP2097105A2 (en) 2009-09-09
EP2097105A4 (en) 2010-09-15
LT2662091T (lt) 2018-12-10
WO2008069999A3 (en) 2008-12-04
US9556266B2 (en) 2017-01-31
PT2662091T (pt) 2018-12-03
WO2008069999A2 (en) 2008-06-12
EP3501538A1 (en) 2019-06-26
EP2662091A3 (en) 2014-03-12

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