IL193398A0 - Substantially pure o-desmethylvenlafaxine and processes for preparing it - Google Patents

Substantially pure o-desmethylvenlafaxine and processes for preparing it

Info

Publication number
IL193398A0
IL193398A0 IL193398A IL19339808A IL193398A0 IL 193398 A0 IL193398 A0 IL 193398A0 IL 193398 A IL193398 A IL 193398A IL 19339808 A IL19339808 A IL 19339808A IL 193398 A0 IL193398 A0 IL 193398A0
Authority
IL
Israel
Prior art keywords
desmethylvenlafaxine
preparing
processes
substantially pure
pure
Prior art date
Application number
IL193398A
Other languages
English (en)
Original Assignee
Teva Pharma
Niddam Hildesheim Valerie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma, Niddam Hildesheim Valerie filed Critical Teva Pharma
Publication of IL193398A0 publication Critical patent/IL193398A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL193398A 2006-04-17 2008-08-12 Substantially pure o-desmethylvenlafaxine and processes for preparing it IL193398A0 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US79280106P 2006-04-17 2006-04-17
US79673906P 2006-05-01 2006-05-01
US87295506P 2006-12-04 2006-12-04
US89916607P 2007-02-01 2007-02-01
US90241807P 2007-02-20 2007-02-20
US90398807P 2007-02-27 2007-02-27
PCT/US2007/009558 WO2007120923A1 (en) 2006-04-17 2007-04-17 Substantially pure o-desmethylvenlafaxine and processes for preparing it

Publications (1)

Publication Number Publication Date
IL193398A0 true IL193398A0 (en) 2009-05-04

Family

ID=39750904

Family Applications (1)

Application Number Title Priority Date Filing Date
IL193398A IL193398A0 (en) 2006-04-17 2008-08-12 Substantially pure o-desmethylvenlafaxine and processes for preparing it

Country Status (6)

Country Link
EP (1) EP2007708A1 (de)
JP (1) JP2008546718A (de)
CA (1) CA2646368A1 (de)
IL (1) IL193398A0 (de)
MX (1) MX2007016172A (de)
WO (1) WO2007120923A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007016179A (es) 2006-04-17 2008-03-11 Teva Pharma Formas cristalinas de o-desmetilvenlafaxina.
WO2008035369A2 (en) * 2006-06-30 2008-03-27 Alembic Limited Novel form of o-desmethyl venlafaxine
CA2656285A1 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
EP1934168A2 (de) 2006-07-26 2008-06-25 Teva Pharmaceutical Industries Ltd Tridesmethylvenlafaxin und verfahren zur synthese von o-desmethylvenlafaxin
US20090069601A1 (en) * 2006-07-26 2009-03-12 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
EP2061750A2 (de) * 2006-08-04 2009-05-27 Medichem, S.A. Verbessertes verfahren zur synthetisierung einer desvenlafaxin-freien base und von salzen oder solvaten daraus
EP2049465A2 (de) * 2007-03-14 2009-04-22 Teva Pharmaceutical Industries Ltd. Verfahren zur herstellung von o-desmethylvenlafaxin in festem zustand
EP2200968A1 (de) * 2007-10-26 2010-06-30 Generics Ýuk¨Limited Verfahren zur herstellung von o-desmethylvenlafaxin
WO2009070311A2 (en) 2007-11-26 2009-06-04 Teva Pharmaceutical Industries Ltd. Crystal forms of o-desmethylvenlafaxine fumarate
WO2009084038A2 (en) * 2007-12-28 2009-07-09 Ind-Swift Laboratories Limited Improved process for the preparation of 0-desmethyl-venlafaxine
CA2717580A1 (en) * 2008-03-06 2009-12-17 Teva Pharmaceutical Industries Ltd. Processes for the preparation of o-desmethylvenlafaxine, free from its dimer impurities
CZ301503B6 (cs) 2008-11-27 2010-03-24 Zentiva, A. S. Zpusob prípravy desvenlafaxinu a jeho solí
ES2343050B1 (es) * 2008-12-16 2011-06-14 Chemo Iberica, S.A. Procedimiento para la preparacion de desvenlafaxina y sus sales de adicion de acido farmaceuticamente aceptables.
CZ200969A3 (cs) 2009-02-06 2010-06-30 Zentiva, K.S. Nové soli desvenlafaxinu a zpusob jejich prípravy
CZ2009454A3 (cs) 2009-07-15 2010-11-10 Zentiva, K. S. Zpusob prípravy desvenlafaxinu a jeho solí
EP2539313A2 (de) 2010-03-29 2013-01-02 Pliva Hrvatska D.O.O. Kristalline formen von o-desmethylvenlafaxinfumarat
CZ303249B6 (cs) 2010-04-06 2012-06-20 Zentiva, K.S. Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
WO2018146529A1 (en) 2017-02-09 2018-08-16 R L Finechem Private Limited A process for preparation of1-[2-(dimethylamino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol and salts thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
EP1905757A1 (de) 1999-04-06 2008-04-02 Sepracor Inc. Derivate von Venlafaxin und Verfahren zu ihrer Herstellung und Verwendung
US6673838B2 (en) 2001-02-12 2004-01-06 Wyeth Succinate salt of O-desmethyl-venlafaxine
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
WO2007071404A1 (en) * 2005-12-20 2007-06-28 Synthon B.V. Process for making desvenlafaxine

Also Published As

Publication number Publication date
JP2008546718A (ja) 2008-12-25
WO2007120923A1 (en) 2007-10-25
CA2646368A1 (en) 2007-10-25
MX2007016172A (es) 2008-03-10
EP2007708A1 (de) 2008-12-31

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