IL192373A - Arginine cyclic peptides and their use in the treatment of fungal infections - Google Patents

Arginine cyclic peptides and their use in the treatment of fungal infections

Info

Publication number
IL192373A
IL192373A IL192373A IL19237308A IL192373A IL 192373 A IL192373 A IL 192373A IL 192373 A IL192373 A IL 192373A IL 19237308 A IL19237308 A IL 19237308A IL 192373 A IL192373 A IL 192373A
Authority
IL
Israel
Prior art keywords
treatment
fungal infections
cyclic peptides
arginine
arginine cyclic
Prior art date
Application number
IL192373A
Other languages
English (en)
Hebrew (he)
Other versions
IL192373A0 (en
Original Assignee
Novabiotics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0526120.1A external-priority patent/GB0526120D0/en
Application filed by Novabiotics Ltd filed Critical Novabiotics Ltd
Publication of IL192373A0 publication Critical patent/IL192373A0/en
Publication of IL192373A publication Critical patent/IL192373A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL192373A 2005-12-22 2008-06-22 Arginine cyclic peptides and their use in the treatment of fungal infections IL192373A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0526120.1A GB0526120D0 (en) 2005-12-22 2005-12-22 Therapeutic peptides
US77650506P 2006-02-24 2006-02-24
PCT/GB2006/004890 WO2007072037A1 (en) 2005-12-22 2006-12-21 Cyclic antimicrobial peptides

Publications (2)

Publication Number Publication Date
IL192373A0 IL192373A0 (en) 2008-12-29
IL192373A true IL192373A (en) 2015-09-24

Family

ID=37836928

Family Applications (2)

Application Number Title Priority Date Filing Date
IL192373A IL192373A (en) 2005-12-22 2008-06-22 Arginine cyclic peptides and their use in the treatment of fungal infections
IL240686A IL240686A (en) 2005-12-22 2015-08-20 Preparations containing cyclic peptides containing adjacent arginine residues

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL240686A IL240686A (en) 2005-12-22 2015-08-20 Preparations containing cyclic peptides containing adjacent arginine residues

Country Status (14)

Country Link
US (2) US8324154B2 (enExample)
EP (4) EP2357190A3 (enExample)
JP (3) JP5559477B2 (enExample)
KR (1) KR101413746B1 (enExample)
AU (1) AU2006327973B2 (enExample)
CA (1) CA2655448C (enExample)
CY (1) CY1113770T1 (enExample)
IL (2) IL192373A (enExample)
MX (1) MX2008008291A (enExample)
NO (1) NO346186B1 (enExample)
PL (1) PL1976863T3 (enExample)
RU (1) RU2463308C2 (enExample)
WO (1) WO2007072037A1 (enExample)
ZA (1) ZA200806329B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2357190A3 (en) * 2005-12-22 2011-08-24 Novabiotics Limited Cyclic antimicrobial peptides
GB0702020D0 (en) * 2007-02-02 2007-03-14 Novabiotics Ltd Peptides and their use
US20110039763A1 (en) 2009-01-06 2011-02-17 C3 Jian, Inc. Targeted antimicrobial moieties
WO2012135846A1 (en) * 2011-04-01 2012-10-04 Northeastern University Methods of eradicating bacterial cell populations
EP2794645A1 (en) * 2011-12-21 2014-10-29 Regents of the University of Minnesota Cationic peptides and use of such peptides for inhibiting exotoxin production
KR101502797B1 (ko) * 2012-08-22 2015-03-17 연세대학교 산학협력단 신규한 양친매성　고리형 펩티드, 이의 제조방법 및 이를 포함하는 안정한 자기조립 나노전달체
US9082888B2 (en) 2012-10-17 2015-07-14 New York University Inverted orthogonal spin transfer layer stack
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
SMT201900441T1 (it) 2014-05-21 2019-09-09 Entrada Therapeutics Inc Peptidi che penetrano nelle cellule e metodi per la loro preparazione e per il loro uso
EP3185880B1 (en) 2014-08-27 2020-02-12 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
CN107614004B (zh) * 2015-03-23 2022-12-06 激流生物科学有限公司 抗微生物肽及其使用方法
KR101692992B1 (ko) 2015-05-20 2017-01-17 연세대학교 산학협력단 고리형 펩타이드의 사전 활성화 합성방법 및 이에 따라 합성된 고리형 펩타이드
US11339192B2 (en) 2017-10-04 2022-05-24 Ohio State Innovation Foundation Bicyclic peptidyl inhibitors
EP3749365A4 (en) 2018-01-29 2022-01-12 Ohio State Innovation Foundation PEPTIDY INHIBITORS OF THE CALCINEURIN-NFAT INTERACTION
WO2019165183A1 (en) 2018-02-22 2019-08-29 Entrada Therapeutics, Inc. Compositions and methods for treating mitochondrial neurogastrointestinal encephalopathy
WO2019217682A1 (en) 2018-05-09 2019-11-14 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
GB202010268D0 (en) * 2020-07-03 2020-08-19 Novabiotics Ltd Nail formulations and treatment regimes
CN115716865B (zh) * 2022-11-24 2024-04-30 安徽农业大学 具有肝癌细胞毒性和α-葡萄糖苷酶抑制活性的环色-苏-酪-缬-亮肽及制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4051842A (en) 1975-09-15 1977-10-04 International Medical Corporation Electrode and interfacing pad for electrical physiological systems
DE2626348C3 (de) 1976-06-11 1980-01-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4962091A (en) 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
US5652211A (en) * 1991-02-11 1997-07-29 Biosynth S.R.L. Peptides for neutralizing the toxicity of Lipid A
CA2145093C (en) 1992-09-25 2007-04-10 Lawrence Leroy Kunz Therapeutic inhibitor of vascular smooth muscle cells
AU727085B2 (en) * 1995-07-20 2000-11-30 Xoma Corporation Anti-fungal peptides
DE19534177A1 (de) * 1995-09-15 1997-03-20 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
US5916872A (en) * 1996-07-24 1999-06-29 Intrabiotics Pharmaceuticals, Inc. Cyclic peptides having broad spectrum antimicrobial activity
US6096707A (en) * 1997-07-11 2000-08-01 Biotie Therapies Ltd. Integrin binding peptide and use thereof
US6951652B2 (en) * 1998-07-29 2005-10-04 Biosynth S.R.L. Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases
JP2004535392A (ja) * 2001-05-04 2004-11-25 ザ スクリプス リサーチ インスティチュート 抗菌ペプチドおよび組成物
US7033991B2 (en) * 2001-07-16 2006-04-25 Board Of Supervisors Of Louisiana State University And Agriculture And Mechanical College Inhibiting furin with polybasic peptides
WO2003093300A2 (en) * 2002-05-06 2003-11-13 The Scripps Research Institute Anti-microbial peptides and compositions
WO2004050685A2 (en) * 2002-11-29 2004-06-17 Adaptive Therapeutics, Inc. Antifungal therapeutic agents
US6783677B1 (en) * 2003-02-06 2004-08-31 Mayyar Systems, Inc. Anaerobic film biogas digester system
AU2004246909B2 (en) * 2003-06-19 2010-08-19 Yeda Research & Development Co. Ltd. Antimicrobial and anticancer lipopeptides
EP1778720B1 (en) * 2004-08-18 2010-09-01 Novabiotics Limited Antimicrobial peptides comprising an arginine- and/or lysine-containing motif
EP2357190A3 (en) * 2005-12-22 2011-08-24 Novabiotics Limited Cyclic antimicrobial peptides

Also Published As

Publication number Publication date
US8785375B2 (en) 2014-07-22
RU2463308C2 (ru) 2012-10-10
NO20083245L (no) 2008-09-12
PL1976863T3 (pl) 2013-07-31
AU2006327973A1 (en) 2007-06-28
CY1113770T1 (el) 2016-07-27
EP1976863A1 (en) 2008-10-08
EP2357191A3 (en) 2011-08-24
IL240686A0 (en) 2015-10-29
WO2007072037A1 (en) 2007-06-28
RU2008129866A (ru) 2010-01-27
IL192373A0 (en) 2008-12-29
AU2006327973B2 (en) 2012-04-12
HK1121462A1 (en) 2009-04-24
JP5559477B2 (ja) 2014-07-23
NO346186B1 (no) 2022-04-11
US8324154B2 (en) 2012-12-04
JP2009520794A (ja) 2009-05-28
CA2655448C (en) 2016-09-06
KR101413746B1 (ko) 2014-07-01
WO2007072037A9 (en) 2009-03-05
JP6050096B2 (ja) 2016-12-21
JP6199797B2 (ja) 2017-09-20
CA2655448A1 (en) 2007-06-28
IL240686A (en) 2017-07-31
EP2357190A3 (en) 2011-08-24
ZA200806329B (en) 2009-12-30
US20090023641A1 (en) 2009-01-22
EP2348039A3 (en) 2011-08-24
KR20080081062A (ko) 2008-09-05
MX2008008291A (es) 2008-09-03
EP1976863B1 (en) 2012-12-12
JP2014167010A (ja) 2014-09-11
EP2357191A2 (en) 2011-08-17
EP2357190A2 (en) 2011-08-17
US20120316103A1 (en) 2012-12-13
JP2013047268A (ja) 2013-03-07
EP2348039A2 (en) 2011-07-27

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