IL174551A0 - Resolution of a narwedine amide derivative - Google Patents
Resolution of a narwedine amide derivativeInfo
- Publication number
- IL174551A0 IL174551A0 IL174551A IL17455106A IL174551A0 IL 174551 A0 IL174551 A0 IL 174551A0 IL 174551 A IL174551 A IL 174551A IL 17455106 A IL17455106 A IL 17455106A IL 174551 A0 IL174551 A0 IL 174551A0
- Authority
- IL
- Israel
- Prior art keywords
- resolution
- amide derivative
- narwedine
- narwedine amide
- derivative
- Prior art date
Links
- QENVUHCAYXAROT-UHFFFAOYSA-N Galanthaminon Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(=O)C=C2 QENVUHCAYXAROT-UHFFFAOYSA-N 0.000 title 1
- WCRYNEMFWLZAAZ-WMLDXEAASA-N Narwedine Natural products COc1ccc2CCCC[C@@]34C=CC(=O)C[C@@H]3Oc1c24 WCRYNEMFWLZAAZ-WMLDXEAASA-N 0.000 title 1
- -1 narwedine amide Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50646903P | 2003-09-26 | 2003-09-26 | |
| PCT/US2004/031936 WO2005030713A2 (en) | 2003-09-26 | 2004-09-27 | Resolution of a narwedine amide derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL174551A0 true IL174551A0 (en) | 2006-08-20 |
Family
ID=34393160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL174551A IL174551A0 (en) | 2003-09-26 | 2006-03-26 | Resolution of a narwedine amide derivative |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7307162B2 (enExample) |
| EP (1) | EP1670767B2 (enExample) |
| JP (1) | JP5020633B2 (enExample) |
| CN (1) | CN1875004B (enExample) |
| AU (1) | AU2004276354B2 (enExample) |
| CA (1) | CA2540248C (enExample) |
| IL (1) | IL174551A0 (enExample) |
| NZ (1) | NZ546768A (enExample) |
| WO (1) | WO2005030713A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090253654A1 (en) | 2005-09-22 | 2009-10-08 | Galantos Pharma Gmbh | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment |
| US7985879B2 (en) * | 2007-04-12 | 2011-07-26 | Scinopharm Taiwan Ltd. | Process for making galantamine |
| ES2463715T3 (es) | 2008-04-14 | 2014-05-29 | Neurodyn Life Sciences Inc. | Derivados de galantamina como profármacos para el tratamiento de enfermedades del cerebro humano |
| WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
| BG66818B1 (bg) | 2013-03-07 | 2019-01-31 | Berbee Beheer B. V. | Състав на екстракт от hippeastrum papilio за производство на лекарствени средства и хранителни добавки |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BG28325A1 (en) * | 1978-11-21 | 1980-04-15 | Vlakhov | Method of obtaining of enons navedine type and their derivatives |
| US4290862A (en) * | 1979-11-14 | 1981-09-22 | Edinen Centar P Chimia | Method for the preparation of narwedine-type enones |
| US5428159A (en) | 1994-04-08 | 1995-06-27 | Ciba-Geigy Corporation | Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine |
| US6407229B1 (en) * | 1994-10-21 | 2002-06-18 | Sanochemia Pharmazeutika Ag | Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2] benzazapine |
| GB9506843D0 (en) * | 1995-04-03 | 1995-05-24 | Chiroscience Ltd | Oxidative process and products thereof |
| US6018043A (en) * | 1995-04-06 | 2000-01-25 | Janssen Pharmaceutica, N.V. | Process for preparing galanthamine derivatives by asymmetric reduction |
| GB9707413D0 (en) * | 1997-04-11 | 1997-05-28 | Chiroscience Ltd | Process |
-
2004
- 2004-09-27 AU AU2004276354A patent/AU2004276354B2/en not_active Ceased
- 2004-09-27 JP JP2006528320A patent/JP5020633B2/ja not_active Expired - Fee Related
- 2004-09-27 CN CN2004800276266A patent/CN1875004B/zh not_active Expired - Fee Related
- 2004-09-27 WO PCT/US2004/031936 patent/WO2005030713A2/en not_active Ceased
- 2004-09-27 CA CA2540248A patent/CA2540248C/en not_active Expired - Fee Related
- 2004-09-27 US US10/951,748 patent/US7307162B2/en not_active Expired - Lifetime
- 2004-09-27 EP EP04789228.6A patent/EP1670767B2/en not_active Expired - Lifetime
- 2004-09-27 NZ NZ546768A patent/NZ546768A/en not_active IP Right Cessation
-
2006
- 2006-03-26 IL IL174551A patent/IL174551A0/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP1670767A4 (en) | 2007-08-29 |
| NZ546768A (en) | 2009-07-31 |
| CN1875004A (zh) | 2006-12-06 |
| WO2005030713A3 (en) | 2006-01-26 |
| WO2005030713A2 (en) | 2005-04-07 |
| US20050070522A1 (en) | 2005-03-31 |
| CA2540248A1 (en) | 2005-04-07 |
| EP1670767B2 (en) | 2014-10-29 |
| EP1670767A2 (en) | 2006-06-21 |
| JP5020633B2 (ja) | 2012-09-05 |
| AU2004276354B2 (en) | 2009-07-09 |
| AU2004276354A1 (en) | 2005-04-07 |
| CN1875004B (zh) | 2010-06-23 |
| US7307162B2 (en) | 2007-12-11 |
| EP1670767B1 (en) | 2011-08-24 |
| JP2007506794A (ja) | 2007-03-22 |
| CA2540248C (en) | 2010-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |