IL166599A0 - Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid - Google Patents
Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acidInfo
- Publication number
- IL166599A0 IL166599A0 IL16659903A IL16659903A IL166599A0 IL 166599 A0 IL166599 A0 IL 166599A0 IL 16659903 A IL16659903 A IL 16659903A IL 16659903 A IL16659903 A IL 16659903A IL 166599 A0 IL166599 A0 IL 166599A0
- Authority
- IL
- Israel
- Prior art keywords
- ethanimidoylamino
- methylhept
- amino
- solid form
- crystalline solid
- Prior art date
Links
- XRYVIWRHMIMIDT-ATPLWMGHSA-N (z,2s)-2-amino-7-(1-aminoethylideneamino)-2-methylhept-5-enoic acid Chemical compound CC(=N)NC\C=C/CC[C@](C)(N)C(O)=O XRYVIWRHMIMIDT-ATPLWMGHSA-N 0.000 title 1
- 239000007787 solid Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40552602P | 2002-08-23 | 2002-08-23 | |
| PCT/US2003/026347 WO2004018412A1 (en) | 2002-08-23 | 2003-08-22 | Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL166599A0 true IL166599A0 (en) | 2006-01-15 |
Family
ID=31946886
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16659903A IL166599A0 (en) | 2002-08-23 | 2003-08-22 | Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid |
| IL166599A IL166599A (en) | 2002-08-23 | 2005-01-31 | Crystalline solid form of (2s-5z) -2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL166599A IL166599A (en) | 2002-08-23 | 2005-01-31 | Crystalline solid form of (2s-5z) -2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6998503B2 (es) |
| EP (1) | EP1534668B1 (es) |
| JP (1) | JP4708024B2 (es) |
| KR (1) | KR100893647B1 (es) |
| CN (1) | CN100588647C (es) |
| AR (1) | AR041038A1 (es) |
| AT (1) | ATE556047T1 (es) |
| AU (1) | AU2003258327B2 (es) |
| BR (1) | BR0313752A (es) |
| CA (1) | CA2494583C (es) |
| ES (1) | ES2384969T3 (es) |
| HK (1) | HK1078562A1 (es) |
| IL (2) | IL166599A0 (es) |
| MX (1) | MXPA05001708A (es) |
| NO (1) | NO20050609L (es) |
| NZ (1) | NZ538184A (es) |
| PL (1) | PL375557A1 (es) |
| RU (1) | RU2314290C2 (es) |
| TW (1) | TWI340133B (es) |
| WO (1) | WO2004018412A1 (es) |
| ZA (1) | ZA200501134B (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9127376D0 (en) | 1991-12-24 | 1992-02-19 | Wellcome Found | Amidino derivatives |
| ES2141347T3 (es) | 1994-03-24 | 2000-03-16 | Searle & Co | Amidino-derivados utiles como inhibidores de oxido nitrico sintasa. |
| US5684008A (en) | 1994-11-09 | 1997-11-04 | G. D. Searle & Co. | Aminotetrazole derivatives useful as nitric oxide synthase inhibitors |
| US5945408A (en) | 1996-03-06 | 1999-08-31 | G.D. Searle & Co. | Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors |
| AR030741A1 (es) * | 2000-09-15 | 2003-09-03 | Pharmacia Corp | Derivados de los acidos 2-amino-2-alquil-5-heptenoico y - heptinoico utiles como inhibidores de oxido nitrico sintetasa |
| GB0031179D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Nitric oxide synthase inhibitors |
| US7012098B2 (en) * | 2001-03-23 | 2006-03-14 | Pharmacia Corporation | Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers |
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2003
- 2003-08-22 US US10/646,266 patent/US6998503B2/en not_active Expired - Fee Related
- 2003-08-22 TW TW092123205A patent/TWI340133B/zh not_active IP Right Cessation
- 2003-08-22 CN CN03820017A patent/CN100588647C/zh not_active Expired - Fee Related
- 2003-08-22 AT AT03793292T patent/ATE556047T1/de active
- 2003-08-22 ES ES03793292T patent/ES2384969T3/es not_active Expired - Lifetime
- 2003-08-22 AR ARP030103042A patent/AR041038A1/es not_active Application Discontinuation
- 2003-08-22 JP JP2004529853A patent/JP4708024B2/ja not_active Expired - Fee Related
- 2003-08-22 NZ NZ538184A patent/NZ538184A/en not_active IP Right Cessation
- 2003-08-22 AU AU2003258327A patent/AU2003258327B2/en not_active Ceased
- 2003-08-22 IL IL16659903A patent/IL166599A0/xx unknown
- 2003-08-22 MX MXPA05001708A patent/MXPA05001708A/es active IP Right Grant
- 2003-08-22 CA CA002494583A patent/CA2494583C/en not_active Expired - Fee Related
- 2003-08-22 BR BR0313752-0A patent/BR0313752A/pt active Search and Examination
- 2003-08-22 EP EP03793292A patent/EP1534668B1/en not_active Expired - Lifetime
- 2003-08-22 RU RU2005104954/04A patent/RU2314290C2/ru not_active IP Right Cessation
- 2003-08-22 PL PL03375557A patent/PL375557A1/xx not_active Application Discontinuation
- 2003-08-22 KR KR1020057002999A patent/KR100893647B1/ko not_active IP Right Cessation
- 2003-08-22 WO PCT/US2003/026347 patent/WO2004018412A1/en not_active Application Discontinuation
-
2005
- 2005-01-31 IL IL166599A patent/IL166599A/en not_active IP Right Cessation
- 2005-02-03 NO NO20050609A patent/NO20050609L/no not_active Application Discontinuation
- 2005-02-08 ZA ZA200501134A patent/ZA200501134B/en unknown
- 2005-11-18 HK HK05110411.5A patent/HK1078562A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1534668A1 (en) | 2005-06-01 |
| CN100588647C (zh) | 2010-02-10 |
| CN1678572A (zh) | 2005-10-05 |
| BR0313752A (pt) | 2005-06-21 |
| TW200413291A (en) | 2004-08-01 |
| NZ538184A (en) | 2008-02-29 |
| NO20050609L (no) | 2005-03-21 |
| MXPA05001708A (es) | 2005-04-19 |
| EP1534668B1 (en) | 2012-05-02 |
| AU2003258327A1 (en) | 2004-03-11 |
| AR041038A1 (es) | 2005-04-27 |
| WO2004018412A1 (en) | 2004-03-04 |
| CA2494583C (en) | 2010-02-02 |
| PL375557A1 (en) | 2005-11-28 |
| ATE556047T1 (de) | 2012-05-15 |
| CA2494583A1 (en) | 2004-03-04 |
| IL166599A (en) | 2010-12-30 |
| ZA200501134B (en) | 2006-10-25 |
| US6998503B2 (en) | 2006-02-14 |
| HK1078562A1 (en) | 2006-03-17 |
| US20040132822A1 (en) | 2004-07-08 |
| ES2384969T3 (es) | 2012-07-16 |
| JP2005536541A (ja) | 2005-12-02 |
| KR20050058443A (ko) | 2005-06-16 |
| TWI340133B (en) | 2011-04-11 |
| KR100893647B1 (ko) | 2009-04-17 |
| RU2005104954A (ru) | 2005-07-20 |
| AU2003258327B2 (en) | 2009-05-21 |
| JP4708024B2 (ja) | 2011-06-22 |
| RU2314290C2 (ru) | 2008-01-10 |
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