IL166010A0 - Piperidine derivatives and their use as selective inhibitors of MIP-1alpha binding to its receptor CCR1 - Google Patents
Piperidine derivatives and their use as selective inhibitors of MIP-1alpha binding to its receptor CCR1Info
- Publication number
- IL166010A0 IL166010A0 IL16601004A IL16601004A IL166010A0 IL 166010 A0 IL166010 A0 IL 166010A0 IL 16601004 A IL16601004 A IL 16601004A IL 16601004 A IL16601004 A IL 16601004A IL 166010 A0 IL166010 A0 IL 166010A0
- Authority
- IL
- Israel
- Prior art keywords
- mip
- selective inhibitors
- piperidine derivatives
- receptor ccr1
- 1alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39710802P | 2002-07-18 | 2002-07-18 | |
PCT/IB2003/002876 WO2004009550A1 (en) | 2002-07-18 | 2003-07-07 | Piperidine derivatives and their use as selective inhibitors of mip-1alpha binding to its receptor ccr1 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL166010A0 true IL166010A0 (en) | 2006-01-15 |
Family
ID=30770997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16601004A IL166010A0 (en) | 2002-07-18 | 2004-12-27 | Piperidine derivatives and their use as selective inhibitors of MIP-1alpha binding to its receptor CCR1 |
Country Status (24)
Country | Link |
---|---|
US (1) | US20040063759A1 (xx) |
EP (1) | EP1534677A1 (xx) |
JP (1) | JP2005537279A (xx) |
KR (1) | KR20050021497A (xx) |
CN (1) | CN1668592A (xx) |
AP (1) | AP2005003200A0 (xx) |
AR (1) | AR040583A1 (xx) |
AU (1) | AU2003242941A1 (xx) |
BR (1) | BR0312946A (xx) |
CA (1) | CA2492651A1 (xx) |
EC (1) | ECSP055547A (xx) |
HN (1) | HN2003000222A (xx) |
IL (1) | IL166010A0 (xx) |
IS (1) | IS7614A (xx) |
MA (1) | MA27326A1 (xx) |
MX (1) | MXPA05000380A (xx) |
OA (1) | OA12885A (xx) |
PA (1) | PA8575901A1 (xx) |
PE (1) | PE20040666A1 (xx) |
TN (1) | TNSN05014A1 (xx) |
TW (1) | TW200402416A (xx) |
UY (1) | UY27897A1 (xx) |
WO (1) | WO2004009550A1 (xx) |
ZA (1) | ZA200500067B (xx) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7399790B2 (en) | 2001-02-28 | 2008-07-15 | Konowalchuk Thomas W | Virucidal compositions |
US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
US7842693B2 (en) | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
DK1531822T3 (da) | 2002-06-12 | 2009-12-07 | Chemocentryx Inc | 1-aryl-4-substituerede piperazin derivater til anvendelse som CCR1 antagonister til behandlingen af inflammation og immunforstyrrelser |
MXPA05000757A (es) * | 2002-07-18 | 2005-04-19 | Pfizer Prod Inc | Derivados de piperidina biciclicos como antagonistas del receptor de quimioquina ccr1. |
US8261062B2 (en) | 2003-03-27 | 2012-09-04 | Microsoft Corporation | Non-cryptographic addressing |
US7479496B2 (en) | 2004-02-19 | 2009-01-20 | Bristol-Myers Squibb Company | Substituted spiro azabicyclics as modulators of chemokine receptor activity |
US7381738B2 (en) | 2004-02-19 | 2008-06-03 | Bristol-Myers Squibb Company | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity |
US7288563B2 (en) | 2004-02-19 | 2007-10-30 | Bristol-Myers Squibb Company | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity |
US7230022B2 (en) | 2004-02-19 | 2007-06-12 | Bristol-Myers Squibb Company | Substituted fused bicyclic amines as modulators of chemokine receptor activity |
US7435831B2 (en) | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
WO2005084667A1 (en) | 2004-03-03 | 2005-09-15 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
US7929689B2 (en) | 2004-06-30 | 2011-04-19 | Microsoft Corporation | Call signs |
GT200500375A (es) * | 2004-12-20 | 2006-11-28 | Derivados de piperidina y su uso como agentes antiinflamatorios | |
US7620902B2 (en) | 2005-04-20 | 2009-11-17 | Microsoft Corporation | Collaboration spaces |
US7617281B2 (en) | 2005-04-25 | 2009-11-10 | Microsoft Corporation | System and method for collaboration with serverless presence |
US7660851B2 (en) | 2005-07-06 | 2010-02-09 | Microsoft Corporation | Meetings near me |
PT1907374E (pt) | 2005-07-26 | 2012-11-05 | Glaxo Group Ltd | Derivados de benzilpiperazina úteis para o tratamento de doenças gastrointestinais |
US7576106B2 (en) | 2005-10-11 | 2009-08-18 | Chemocentryx, Inc. | Piperidine derivatives and methods of use |
US8086842B2 (en) | 2006-04-21 | 2011-12-27 | Microsoft Corporation | Peer-to-peer contact exchange |
US8069208B2 (en) | 2006-04-21 | 2011-11-29 | Microsoft Corporation | Peer-to-peer buddy request and response |
WO2009051244A1 (ja) * | 2007-10-18 | 2009-04-23 | Takeda Pharmaceutical Company Limited | 複素環化合物 |
US20100168080A1 (en) * | 2008-12-17 | 2010-07-01 | Khamrai Uttam | Novel compounds useful as cc chemokine receptor ligands |
CN105829296A (zh) | 2013-12-18 | 2016-08-03 | 巴斯夫欧洲公司 | 带有亚胺衍生的取代基的唑类化合物 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE640616A (xx) * | 1962-12-19 | |||
US3492397A (en) * | 1967-04-07 | 1970-01-27 | Warner Lambert Pharmaceutical | Sustained release dosage in the pellet form and process thereof |
US4060598A (en) * | 1967-06-28 | 1977-11-29 | Boehringer Mannheim G.M.B.H. | Tablets coated with aqueous resin dispersions |
US3538214A (en) * | 1969-04-22 | 1970-11-03 | Merck & Co Inc | Controlled release medicinal tablets |
US4173626A (en) * | 1978-12-11 | 1979-11-06 | Merck & Co., Inc. | Sustained release indomethacin |
AU1208397A (en) * | 1995-12-28 | 1997-07-28 | Takeda Chemical Industries Ltd. | Diphenylmethane derivatives as mip-1alpha/rantes receptor antagonists |
CA2373942A1 (en) * | 1999-05-18 | 2000-11-23 | Teijin Limited | Remedies or prophylactis for diseases in association with chemokines |
AR028947A1 (es) * | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
ATE408611T1 (de) * | 2001-07-24 | 2008-10-15 | Richter Gedeon Nyrt | Piperidine als nmda-rezeptorantagonisten |
-
2003
- 2003-06-17 PA PA20038575901A patent/PA8575901A1/es unknown
- 2003-07-07 CN CNA038170922A patent/CN1668592A/zh active Pending
- 2003-07-07 OA OA1200500010A patent/OA12885A/en unknown
- 2003-07-07 MX MXPA05000380A patent/MXPA05000380A/es unknown
- 2003-07-07 KR KR10-2005-7000849A patent/KR20050021497A/ko not_active Application Discontinuation
- 2003-07-07 AU AU2003242941A patent/AU2003242941A1/en not_active Abandoned
- 2003-07-07 JP JP2004522601A patent/JP2005537279A/ja active Pending
- 2003-07-07 BR BR0312946-2A patent/BR0312946A/pt not_active Application Discontinuation
- 2003-07-07 CA CA002492651A patent/CA2492651A1/en not_active Abandoned
- 2003-07-07 EP EP03765230A patent/EP1534677A1/en not_active Withdrawn
- 2003-07-07 AP AP2005003200A patent/AP2005003200A0/xx unknown
- 2003-07-07 WO PCT/IB2003/002876 patent/WO2004009550A1/en not_active Application Discontinuation
- 2003-07-08 US US10/616,844 patent/US20040063759A1/en not_active Abandoned
- 2003-07-15 PE PE2003000705A patent/PE20040666A1/es not_active Application Discontinuation
- 2003-07-16 UY UY27897A patent/UY27897A1/es not_active Application Discontinuation
- 2003-07-16 AR AR20030102555A patent/AR040583A1/es unknown
- 2003-07-17 HN HN2003000222A patent/HN2003000222A/es unknown
- 2003-07-17 TW TW092119550A patent/TW200402416A/zh unknown
-
2004
- 2004-12-23 IS IS7614A patent/IS7614A/is unknown
- 2004-12-27 IL IL16601004A patent/IL166010A0/xx unknown
-
2005
- 2005-01-04 ZA ZA200500067A patent/ZA200500067B/en unknown
- 2005-01-18 EC EC2005005547A patent/ECSP055547A/es unknown
- 2005-01-18 MA MA28049A patent/MA27326A1/fr unknown
- 2005-01-18 TN TNP2005000014A patent/TNSN05014A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
JP2005537279A (ja) | 2005-12-08 |
PA8575901A1 (es) | 2004-07-20 |
BR0312946A (pt) | 2005-07-12 |
HN2003000222A (es) | 2004-11-23 |
CN1668592A (zh) | 2005-09-14 |
TNSN05014A1 (fr) | 2007-05-14 |
AP2005003200A0 (en) | 2005-03-31 |
OA12885A (en) | 2006-09-15 |
PE20040666A1 (es) | 2004-09-25 |
US20040063759A1 (en) | 2004-04-01 |
UY27897A1 (es) | 2004-02-27 |
CA2492651A1 (en) | 2004-01-29 |
EP1534677A1 (en) | 2005-06-01 |
IS7614A (is) | 2004-12-23 |
MA27326A1 (fr) | 2005-05-02 |
AR040583A1 (es) | 2005-04-13 |
ZA200500067B (en) | 2005-11-02 |
ECSP055547A (es) | 2005-03-10 |
KR20050021497A (ko) | 2005-03-07 |
TW200402416A (en) | 2004-02-16 |
AU2003242941A1 (en) | 2004-02-09 |
WO2004009550A1 (en) | 2004-01-29 |
MXPA05000380A (es) | 2005-03-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL166010A0 (en) | Piperidine derivatives and their use as selective inhibitors of MIP-1alpha binding to its receptor CCR1 | |
ZA200500680B (en) | Quinoline derivatives and their use as mycrobacterial inhibitors | |
HK1094203A1 (en) | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | |
AU2003298514A8 (en) | Methods and compositions using cholinesterase inhibitors | |
IL173398A0 (en) | Pyridyl derivatives and their use as therapeutic agents | |
IL174334A0 (en) | Use of chk1 inhibitors to control cell proliferation | |
EP1601357A4 (en) | HETEROCYCLIC KINASE INHIBITORS: METHOD OF USE AND SYNTHESIS | |
IL182527A0 (en) | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | |
EP1656378A4 (en) | COMPOUNDS AND COMPOSITIONS INHIBITING TYROSINE KINASE RECEPTOR ACTIVITY | |
PL375877A1 (en) | Hydantoine derivatives and their use as tace inhibitors | |
IL175179A0 (en) | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors | |
AU2003302919A1 (en) | Pyridine derivatives as jnk inhibitors and their use | |
EP1675847A4 (en) | SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF USE | |
IL174497A0 (en) | Pyridine derivatives and use thereof as urotensin ii antagonists | |
SI1709018T1 (sl) | Acilaminotiazolni derivati in njihova uporaba kotbeta-amiloidni inhibitorji | |
EP1763346A4 (en) | COMPOSITION AND METHODS RELATING TO INHIBITORS OF PYRIMIDINE SYNTHESIS | |
AU2003232848A8 (en) | Phenylaminopyrimidines and their use as rho-kinase inhibitors | |
ZA200606070B (en) | Substituted quinolines and their use as mycrobacterial inhibitors | |
AU2003215756A8 (en) | Benzimidazoles and their use as mitogen-activated- and rho-kinase inhibitors | |
EP1703907A4 (en) | COMPOSITIONS AND METHODS FOR TREATING RECURRENT CONDITIONS | |
EP1638565A4 (en) | SUBSTITUTED PIPERIDINE COMPOUNDS AND METHOD OF USE THEREOF | |
AU2003269421A8 (en) | Hiv-integrase inhibitors, pharmaceutical compositions, and methods for their use | |
IL179038A0 (en) | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases | |
EP1627048A4 (en) | Compositions for Downregulating CCR5 Expression and Method of Use Therefor | |
AU2003218715A8 (en) | Azepane derivatives and their use as atk1 inhibitors |