IL163529A0 - Novel spinosyn-producing polyketidesynthases - Google Patents

Novel spinosyn-producing polyketidesynthases

Info

Publication number
IL163529A0
IL163529A0 IL16352903A IL16352903A IL163529A0 IL 163529 A0 IL163529 A0 IL 163529A0 IL 16352903 A IL16352903 A IL 16352903A IL 16352903 A IL16352903 A IL 16352903A IL 163529 A0 IL163529 A0 IL 163529A0
Authority
IL
Israel
Prior art keywords
polyketidesynthases
producing
novel spinosyn
spinosyn
novel
Prior art date
Application number
IL16352903A
Other languages
English (en)
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of IL163529A0 publication Critical patent/IL163529A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Catching Or Destruction (AREA)
IL16352903A 2002-02-19 2003-02-19 Novel spinosyn-producing polyketidesynthases IL163529A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35807502P 2002-02-19 2002-02-19
PCT/US2003/004998 WO2003070908A2 (en) 2002-02-19 2003-02-19 Novel spinosyn-producing polyketide synthases

Publications (1)

Publication Number Publication Date
IL163529A0 true IL163529A0 (en) 2005-12-18

Family

ID=27757699

Family Applications (3)

Application Number Title Priority Date Filing Date
IL16352903A IL163529A0 (en) 2002-02-19 2003-02-19 Novel spinosyn-producing polyketidesynthases
IL16352904A IL163529A (en) 2002-02-19 2004-08-12 Spinosyn-producing polyketide synthases
IL200471A IL200471A (en) 2002-02-19 2009-08-18 Polynucleide syntheses produce spinosine

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL16352904A IL163529A (en) 2002-02-19 2004-08-12 Spinosyn-producing polyketide synthases
IL200471A IL200471A (en) 2002-02-19 2009-08-18 Polynucleide syntheses produce spinosine

Country Status (11)

Country Link
US (5) US20030225006A1 (zh)
EP (1) EP1492404B1 (zh)
JP (1) JP4765032B2 (zh)
KR (1) KR101016561B1 (zh)
CN (1) CN1633237B (zh)
AU (2) AU2003217591B2 (zh)
DK (1) DK1492404T3 (zh)
ES (1) ES2375714T3 (zh)
IL (3) IL163529A0 (zh)
MX (1) MXPA04008071A (zh)
WO (1) WO2003070908A2 (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225006A1 (en) * 2002-02-19 2003-12-04 Burns Lesley S Novel spinosyn-producing polyketide synthases
GB0327720D0 (en) 2003-11-28 2003-12-31 Biotica Tech Ltd Erythromycins and process for their preparation
GB0417852D0 (en) 2004-08-11 2004-09-15 Biotica Tech Ltd Production of polyketides and other natural products
WO2007144786A2 (en) * 2006-05-26 2007-12-21 Entarco Sa The vapor-phase application of spinosyn for the control of pests, and formulations and products utilizing the same
DK2343975T3 (da) * 2008-09-22 2012-12-03 Entarco Sa Spinosyn-antibegroningssammensætninger, fremgangsmåder til deres anvendelse samt genstande beskyttet mod vedhæftning af biobegroningsorganismer
NZ594163A (en) * 2009-02-11 2012-11-30 Dow Agrosciences Llc Pyranose derivatives of pestcidal 1,2,4-triazoles
KR101586680B1 (ko) * 2009-04-03 2016-01-19 다우 아그로사이언시즈 엘엘씨 수성 에멀젼을 항유화 및 분리하는 항유화 조성물, 시스템 및 방법
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions
EP2445506B1 (en) 2009-06-24 2014-12-31 Entarco SA The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
EP2272963A1 (en) * 2009-07-09 2011-01-12 LEK Pharmaceuticals d.d. Process for Preparation of Tacrolimus
KR20130080007A (ko) 2010-05-11 2013-07-11 다우 아그로사이언시즈 엘엘씨 Ｓｐｎｋ 균주
CN101942425B (zh) * 2010-08-24 2012-06-20 北京农学院 与苯亚甲基丙酮合成相关的酶及其编码基因与应用
WO2012085683A1 (en) 2010-12-22 2012-06-28 Entarco Sa The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
DK2520653T3 (en) 2011-05-03 2017-07-03 Dow Agrosciences Llc INTEGRATION OF GENES IN THE CHROMOSOME OF SACCHAROPOLYSPORA SPINOSA
US9404107B2 (en) 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
US9631195B2 (en) * 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
WO2016074221A1 (zh) * 2014-11-14 2016-05-19 浙江海正药业股份有限公司 多杀菌素异源表达菌株及其构建方法和应用
AU2016317848A1 (en) * 2015-09-03 2018-03-15 Agrimetis, Llc Spinosyn derivatives as insecticides
WO2018226893A2 (en) 2017-06-06 2018-12-13 Zymergen Inc. A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1117005A (en) 1978-03-07 1982-01-26 Patrick G. Feakins Animal ear-tags, their manufacture and their use
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
OA09249A (fr) 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
WO1993013663A1 (en) 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
US5539089A (en) * 1991-11-08 1996-07-23 Dowelanco A83543 aglycones and pseudoglycones
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
WO1994020518A1 (en) 1993-03-12 1994-09-15 Dowelanco New a83543 compounds and process for production thereof
CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
NZ333861A (en) * 1996-07-05 2000-08-25 Pfizer Erythromycins and preparation from unnatural starter units in microorganisms
JP3441899B2 (ja) 1996-11-01 2003-09-02 理化学研究所 完全長ｃＤＮＡライブラリーの作成方法
CA2715841A1 (en) 1997-12-23 1999-07-08 Syngenta Participations Ag Use of macrolides in pest control
US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
DE19823397B4 (de) 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
GB9814006D0 (en) * 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
SK20062000A3 (sk) 1998-07-02 2002-02-05 Eli Lilly And Company Prostriedok proti ľudským všiam
GB9814622D0 (en) * 1998-07-06 1998-09-02 Biotica Tech Ltd Polyketides,their preparation,and materials for use therein
CN1329668A (zh) * 1998-10-02 2002-01-02 高山生物科学股份有限公司 多聚乙酰合成酶及其重组dna构建物
DE19857966A1 (de) 1998-12-16 2000-06-21 Bayer Ag Wirkstoffkombinationen
DE19857967A1 (de) 1998-12-16 2000-06-21 Bayer Ag Wirkstoffkombinationen
AU3353500A (en) * 1999-01-27 2000-08-18 Kosan Biosciences, Inc. Synthesis of oligoketides
JP2000245457A (ja) * 1999-02-24 2000-09-12 Kitasato Inst:The エバーメクチンアグリコン合成酵素遺伝子
DE19913174A1 (de) 1999-03-24 2000-09-28 Bayer Ag Synergistische insektizide Mischungen
GB9912563D0 (en) * 1999-05-28 1999-07-28 Biotica Tech Ltd Polyketides and their synthesis
EP1212412A2 (de) * 1999-08-27 2002-06-12 Bayer Ag Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren
DE60015161T2 (de) * 1999-09-13 2006-02-02 Dow Agrosciences Llc, Indianapolis Pestizide makrolide
AU2001279771A1 (en) * 2000-07-20 2002-02-05 Campina B.V. Carrier material for dry powder inhalation
GB0019986D0 (en) * 2000-08-14 2000-10-04 Biotica Tech Ltd Polyketides and their synthesis
US6919464B1 (en) * 2001-03-21 2005-07-19 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
TWI275592B (en) * 2001-03-21 2007-03-11 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
DE10135550A1 (de) * 2001-07-20 2003-01-30 Bayer Cropscience Ag Verfahren zum Herstellen von neuen Spinosyn-Derivaten
US20030225006A1 (en) * 2002-02-19 2003-12-04 Burns Lesley S Novel spinosyn-producing polyketide synthases
WO2005109887A1 (en) * 2004-04-23 2005-11-17 Smart Metric, Inc. Smartcard with visual display

Also Published As

Publication number Publication date
IL200471A (en) 2015-09-24
AU2003217591B2 (en) 2009-02-26
US20140080777A1 (en) 2014-03-20
IL163529A (en) 2011-11-30
US8624009B2 (en) 2014-01-07
CN1633237B (zh) 2010-05-26
DK1492404T3 (da) 2012-04-23
US20060040877A1 (en) 2006-02-23
EP1492404A2 (en) 2005-01-05
AU2003217591A1 (en) 2003-09-09
CN1633237A (zh) 2005-06-29
AU2009200685A1 (en) 2009-03-12
KR20040085201A (ko) 2004-10-07
EP1492404A4 (en) 2010-03-17
US20110178036A1 (en) 2011-07-21
MXPA04008071A (es) 2004-11-26
KR101016561B1 (ko) 2011-02-22
ES2375714T3 (es) 2012-03-05
US7626010B2 (en) 2009-12-01
EP1492404B1 (en) 2011-12-28
JP2005520500A (ja) 2005-07-14
IL200471A0 (en) 2011-07-31
US20030225006A1 (en) 2003-12-04
WO2003070908A3 (en) 2004-10-28
US20100068785A1 (en) 2010-03-18
US9137992B2 (en) 2015-09-22
WO2003070908A2 (en) 2003-08-28
JP4765032B2 (ja) 2011-09-07
AU2009200685B2 (en) 2012-01-12

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