IL162447A0 - Methods for slowing senescence and treating and preventing diseases associated with senescence - Google Patents
Methods for slowing senescence and treating and preventing diseases associated with senescenceInfo
- Publication number
- IL162447A0 IL162447A0 IL16244702A IL16244702A IL162447A0 IL 162447 A0 IL162447 A0 IL 162447A0 IL 16244702 A IL16244702 A IL 16244702A IL 16244702 A IL16244702 A IL 16244702A IL 162447 A0 IL162447 A0 IL 162447A0
- Authority
- IL
- Israel
- Prior art keywords
- senescence
- treating
- methods
- slowing
- diseases associated
- Prior art date
Links
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- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
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- Biomedical Technology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Urology & Nephrology (AREA)
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Applications Claiming Priority (10)
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US34050201P | 2001-12-19 | 2001-12-19 | |
US36985702P | 2002-04-05 | 2002-04-05 | |
US38362402P | 2002-05-29 | 2002-05-29 | |
US38557702P | 2002-06-05 | 2002-06-05 | |
US38556102P | 2002-06-05 | 2002-06-05 | |
US38555902P | 2002-06-05 | 2002-06-05 | |
US38557602P | 2002-06-05 | 2002-06-05 | |
US38556002P | 2002-06-05 | 2002-06-05 | |
US38557502P | 2002-06-05 | 2002-06-05 | |
PCT/US2002/040368 WO2003053219A2 (en) | 2001-12-19 | 2002-12-19 | Methods for slowing senescence and treating and preventing diseases associated with senescence |
Publications (1)
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IL162447A0 true IL162447A0 (en) | 2005-11-20 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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IL16244702A IL162447A0 (en) | 2001-12-19 | 2002-12-19 | Methods for slowing senescence and treating and preventing diseases associated with senescence |
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US (3) | US20030144203A1 (de) |
EP (1) | EP1503779A4 (de) |
JP (1) | JP2005523885A (de) |
CN (1) | CN1612745A (de) |
AU (1) | AU2002361744A1 (de) |
BR (1) | BR0215168A (de) |
CA (1) | CA2470576A1 (de) |
EA (1) | EA200400825A1 (de) |
IL (1) | IL162447A0 (de) |
MX (1) | MXPA04005885A (de) |
WO (1) | WO2003053219A2 (de) |
Families Citing this family (42)
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DE10137174A1 (de) * | 2001-07-31 | 2003-02-13 | Zentaris Ag | Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität |
WO2005025601A1 (en) * | 2003-09-15 | 2005-03-24 | Monash University | Follistatin isoforms and uses thereof |
CN1622677A (zh) * | 2003-11-27 | 2005-06-01 | 皇家飞利浦电子股份有限公司 | 一种无线通信网络中支持点到点通信切换的方法 |
WO2005077404A1 (en) * | 2004-02-13 | 2005-08-25 | Stem Cell Therapeutics Corp. | Use of luteinizing hormone (lh) and chorionic gonadotropin (hcg) for proliferation of neural stem cells and neurogenesis |
EP1771470B1 (de) | 2004-07-23 | 2013-06-26 | Acceleron Pharma Inc. | Actrii-rezeptorpolypeptide, verfahren und zusammensetzungen |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
US8435948B2 (en) * | 2004-09-29 | 2013-05-07 | Mount Sinai School Of Medicine Of New York University | Methods for inhibiting osteoclastic bone resorption and bone loss comprising administration of an anti-FSH or anti-FSHR antibody |
CA2609244A1 (en) * | 2005-06-01 | 2006-12-07 | Pfizer Products Inc. | Vaccine compositions and methods for the treatment of urinary incontinence |
WO2007011339A1 (en) * | 2005-07-14 | 2007-01-25 | Voyager Pharmaceutical Corporation | Methods for treating and preventing brain cancers |
US8128933B2 (en) * | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
KR20190006086A (ko) | 2005-11-23 | 2019-01-16 | 악셀레론 파마 인코포레이티드 | 액티빈-actrⅱa 길항제 및 골 성장을 촉진하기 위한 이들의 용도 |
WO2008060139A1 (en) * | 2006-11-17 | 2008-05-22 | Erasmus University Medical Center Rotterdam | Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein |
US20100028332A1 (en) * | 2006-12-18 | 2010-02-04 | Acceleron Pharma Inc. | Antagonists of actriib and uses for increasing red blood cell levels |
CN105582521A (zh) * | 2006-12-18 | 2016-05-18 | 阿塞勒隆制药公司 | 活化素-actrii拮抗剂及在提高红细胞水平中的用途 |
US8895016B2 (en) * | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
EP2111229B1 (de) * | 2007-02-01 | 2013-04-10 | Acceleron Pharma, Inc. | Zusammensetzungen enthaltend Activin-ActRIIA-Antagonisten zur Verwendung bei der Vorbeugung oder Behandlung der Brustkrebs-Metastasen oder des Brustkrebs Knochenverlustes |
TWI548647B (zh) * | 2007-02-02 | 2016-09-11 | 艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
EP2120999B1 (de) * | 2007-02-09 | 2012-08-29 | Acceleron Pharma, Inc. | Zusammensetzungen enthaltend Activin-ActRIIA-Antagonisten und deren Verwendung bei der Verbeugung oder Behandlung des Multiplen Myeloms |
CN103877564A (zh) * | 2007-09-18 | 2014-06-25 | 阿塞勒隆制药公司 | 活化素-actriia拮抗剂和减少或抑制fsh分泌的用途 |
US20090263363A1 (en) * | 2008-04-22 | 2009-10-22 | Northwestern University | Compositions and Methods For Treating Bone Formation Disorders |
US20100008918A1 (en) * | 2008-06-26 | 2010-01-14 | Acceleron Pharma Inc. | Methods for dosing an actriib antagonist and monitoring of treated patients |
LT3750552T (lt) | 2008-08-14 | 2023-06-26 | Acceleron Pharma Inc. | Gdf gaudyklės |
US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
EP2387412A4 (de) | 2009-01-13 | 2013-04-03 | Acceleron Pharma Inc | Verfahren zur erhöhung des adiponectin-spiegels |
BRPI1010587A2 (pt) | 2009-06-08 | 2019-04-09 | Acceleron Pharma Inc. | métodos para aumentar adipócitos termogênicos |
EP2440577A4 (de) | 2009-06-12 | 2013-01-23 | Acceleron Pharma Inc | Verkürzte actriib-fc-fusionsproteine |
WO2011026242A1 (en) | 2009-09-03 | 2011-03-10 | Vancouver Biotech Ltd. | Monoclonal antibodies against gonadotropin-releasing hormone receptor |
US20110070233A1 (en) * | 2009-09-09 | 2011-03-24 | Acceleron Pharma Inc. | Actriib antagonists and dosing and uses thereof |
CA2779472C (en) * | 2009-11-03 | 2021-03-16 | Acceleron Pharma Inc. | The use of a composition comprising an activin type iib receptor polypeptide in the treatment of fatty liver disease |
US8710016B2 (en) | 2009-11-17 | 2014-04-29 | Acceleron Pharma, Inc. | ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy |
JP2014502260A (ja) | 2010-11-08 | 2014-01-30 | アクセルロン ファーマ, インコーポレイテッド | Actriia結合剤およびその使用 |
MX366336B (es) | 2012-11-02 | 2019-07-05 | Celgene Corp | Antagonistas de activina - actrii y usos para el tratar trastornos oseos y otros. |
SG10201703586PA (en) | 2012-11-02 | 2017-06-29 | Murray & Poole Entpr Ltd | Treatment or prevention of cardiovascular events via the administration of a colchicine derivative |
CN105307643A (zh) | 2013-04-16 | 2016-02-03 | 默里和普尔企业有限公司 | 秋水仙碱的缓释制剂及其使用方法 |
BR122023023170A2 (pt) | 2014-06-13 | 2024-02-20 | Acceleron Pharma Inc. | Uso de um antagonista de actrii no tratamento ou prevenção de úlcera cutânea associada com beta-talassemia |
JP2017529388A (ja) | 2014-08-26 | 2017-10-05 | ベタニエン ホスピタル | 炎症性病態の治療のための方法、薬剤および組成物 |
MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
AU2015358469B2 (en) | 2014-12-03 | 2021-05-27 | Acceleron Pharma Inc. | Activin-ActRII antagonists and uses for treating anemia |
PL3496739T3 (pl) | 2016-07-15 | 2021-10-11 | Acceleron Pharma Inc. | Kompozycje zawierające polipeptydy actriia do stosowania w leczeniu nadciśnienia płucnego |
WO2018218273A1 (en) * | 2017-05-29 | 2018-12-06 | Paranta Biosciences Limited | Method of treating hypertension and kidney disease |
WO2019046903A1 (en) * | 2017-09-08 | 2019-03-14 | Baker Heart and Diabetes Institute | THERAPEUTIC METHOD FOR INCREASING MUSCLE MASS IN A SUBJECT |
CN110393790B (zh) * | 2018-04-24 | 2023-03-28 | 中国科学院分子细胞科学卓越创新中心 | 促黄体生成素在抑制髓系白血病发展的用途 |
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US3816386A (en) * | 1972-06-20 | 1974-06-11 | Abbott Lab | Purification process for gn-rh |
US4005063A (en) * | 1973-10-11 | 1977-01-25 | Abbott Laboratories | [Des-gly]10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity |
DE2438350C3 (de) * | 1974-08-09 | 1979-06-13 | Hoechst Ag, 6000 Frankfurt | Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
GB1524747A (en) * | 1976-05-11 | 1978-09-13 | Ici Ltd | Polypeptide |
US4075192A (en) * | 1977-06-13 | 1978-02-21 | Parke, Davis & Company | Nonapeptides and methods for their production |
US4234571A (en) * | 1979-06-11 | 1980-11-18 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone |
US4244946A (en) * | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
US4762717A (en) * | 1986-03-21 | 1988-08-09 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive |
CA1283072C (en) * | 1986-12-01 | 1991-04-16 | Timothy Durance | Process for the isolation and separation of lysozyme and avidin from eggwhite |
US5102868A (en) * | 1990-01-08 | 1992-04-07 | Genentech, Inc. | Method for inhibiting follicular maturation |
US5753612A (en) * | 1992-10-27 | 1998-05-19 | Yissum Research Development Co. Of The Hebrew University Of Jerusalem | Pharmaceutical composition and method for inhibiting hair growth by administration of activin or activin agonists |
US6242421B1 (en) * | 1997-11-06 | 2001-06-05 | Richard Lloyd Bowen | Methods for preventing and treating Alzheimer's disease |
US5942420A (en) * | 1997-11-17 | 1999-08-24 | Millennium Biotherapeutics, Inc. | Molecules of the follistatin-related protein family and uses therefor |
US6004937A (en) * | 1998-03-09 | 1999-12-21 | Genetics Institute, Inc. | Use of follistatin to modulate growth and differentiation factor 8 [GDF-8] and bone morphogenic protein 11 [BMP-11] |
US6197337B1 (en) * | 1999-05-10 | 2001-03-06 | Kenneth Weisman | Therapeutic uses of abarelix |
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- 2002-12-19 EA EA200400825A patent/EA200400825A1/ru unknown
- 2002-12-19 AU AU2002361744A patent/AU2002361744A1/en not_active Abandoned
- 2002-12-19 IL IL16244702A patent/IL162447A0/xx unknown
- 2002-12-19 MX MXPA04005885A patent/MXPA04005885A/es not_active Application Discontinuation
- 2002-12-19 CN CNA028269837A patent/CN1612745A/zh active Pending
- 2002-12-19 EP EP02797381A patent/EP1503779A4/de not_active Withdrawn
- 2002-12-19 WO PCT/US2002/040368 patent/WO2003053219A2/en active Search and Examination
- 2002-12-19 BR BR0215168-5A patent/BR0215168A/pt not_active IP Right Cessation
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- 2002-12-19 CA CA002470576A patent/CA2470576A1/en not_active Abandoned
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2007
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2010
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CN1612745A (zh) | 2005-05-04 |
WO2003053219A2 (en) | 2003-07-03 |
EP1503779A2 (de) | 2005-02-09 |
US20100267620A1 (en) | 2010-10-21 |
EA200400825A1 (ru) | 2005-08-25 |
CA2470576A1 (en) | 2003-07-03 |
US20030144203A1 (en) | 2003-07-31 |
US20070173454A1 (en) | 2007-07-26 |
EP1503779A4 (de) | 2005-12-14 |
BR0215168A (pt) | 2005-05-31 |
MXPA04005885A (es) | 2005-05-17 |
AU2002361744A1 (en) | 2003-07-09 |
WO2003053219A3 (en) | 2004-12-09 |
JP2005523885A (ja) | 2005-08-11 |
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