IL162255A0 - Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof - Google Patents

Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof

Info

Publication number
IL162255A0
IL162255A0 IL16225502A IL16225502A IL162255A0 IL 162255 A0 IL162255 A0 IL 162255A0 IL 16225502 A IL16225502 A IL 16225502A IL 16225502 A IL16225502 A IL 16225502A IL 162255 A0 IL162255 A0 IL 162255A0
Authority
IL
Israel
Prior art keywords
preparation
methods
crystalline polymorph
novel crystalline
venlafaxine hydrochloride
Prior art date
Application number
IL16225502A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of IL162255A0 publication Critical patent/IL162255A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL16225502A 2001-12-05 2002-12-03 Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof IL162255A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33582201P 2001-12-05 2001-12-05
PCT/US2002/038401 WO2003050075A1 (fr) 2001-12-05 2002-12-03 Nouvelle forme cristalline polymorphe d'hydrochlorure de venlafaxine et methodes de preparation de ladite forme

Publications (1)

Publication Number Publication Date
IL162255A0 true IL162255A0 (en) 2005-11-20

Family

ID=23313356

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16225502A IL162255A0 (en) 2001-12-05 2002-12-03 Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof

Country Status (21)

Country Link
US (2) US7030164B2 (fr)
EP (1) EP1451145A1 (fr)
JP (1) JP2005511736A (fr)
KR (1) KR20050044673A (fr)
CN (1) CN1630631A (fr)
AR (1) AR037744A1 (fr)
AU (1) AU2002348266A1 (fr)
BR (1) BR0214742A (fr)
CA (1) CA2467593A1 (fr)
CO (1) CO5580818A2 (fr)
EC (1) ECSP045136A (fr)
HU (1) HUP0402524A2 (fr)
IL (1) IL162255A0 (fr)
MX (1) MXPA04005305A (fr)
NO (1) NO20042681L (fr)
NZ (1) NZ533363A (fr)
PL (1) PL370552A1 (fr)
RU (1) RU2004120285A (fr)
TW (1) TW200301101A (fr)
WO (1) WO2003050075A1 (fr)
ZA (1) ZA200405248B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
EP1330427A1 (fr) * 2000-10-31 2003-07-30 Ciba SC Holding AG Formes cristallines de chlorhydrate de venlafaxine
CN101014337A (zh) * 2004-07-22 2007-08-08 惠氏公司 治疗神经系统障碍和病症的方法
EP1773321A2 (fr) * 2004-07-22 2007-04-18 Wyeth Procede de traitement des pathologies et des troubles du systeme nerveux
CA2574310A1 (fr) * 2004-07-22 2006-02-02 Wyeth Procede pour le traitement de troubles et affections du systeme nerveux
US20070021488A1 (en) * 2005-07-21 2007-01-25 Wyeth Method for treating nervous system disorders and conditions
JP2009511641A (ja) * 2005-10-19 2009-03-19 テバ ファーマシューティカル インダストリーズ リミティド 高純度1−〔2−ジメチルアミノ−(4−メトキシフェニル)エチル〕シクロヘキサノール塩酸塩の調製方法
ES2609264T3 (es) * 2007-02-21 2017-04-19 Sepracor Inc. Formas sólidas que comprenden (-)-O-desmetilvenlafaxina y usos de las mismas
DK2621891T3 (da) * 2010-10-01 2020-02-17 Shan Dong Luye Pharm Co Ltd Polymorfer af 4-[2-dimethylamino-1-(1 hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoathydrochlorid, fremgangsmåder til fremstilling og anvendelse deraf
US9346800B2 (en) 2012-09-18 2016-05-24 Auspex Pharmaceuticals, Inc. Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
KR20240049625A (ko) 2015-03-06 2024-04-16 오스펙스 파마슈티칼스, 인코포레이티드 비정상적 불수의 운동 장애의 치료 방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761501A (en) * 1983-10-26 1988-08-02 American Home Products Corporation Substituted phenylacetamides
US6440457B1 (en) 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
EP1738753B1 (fr) * 1993-06-28 2008-04-23 Wyeth Nouveaux traitements utilisant des dérivés de phenéthyleamine
TW344661B (en) * 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
US5530013A (en) * 1994-02-14 1996-06-25 American Home Products Corporation Venlafaxine in the inducement of cognition enhancement
US5506270A (en) * 1995-01-30 1996-04-09 American Home Products Corporation Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women
US6274171B1 (en) * 1996-03-25 2001-08-14 American Home Products Corporation Extended release formulation of venlafaxine hydrochloride
UA77145C2 (en) * 1997-11-05 2006-11-15 Wyeth Corp Extended release dosage formulation
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
US20020143211A1 (en) 2000-10-19 2002-10-03 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochlorid, processes for preparing thereof
EP1330427A1 (fr) 2000-10-31 2003-07-30 Ciba SC Holding AG Formes cristallines de chlorhydrate de venlafaxine
AU2001235970A1 (en) 2000-12-07 2002-06-18 Dr. Reddy's Research Foundation Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation
UA77234C2 (en) * 2001-12-05 2006-11-15 Wyeth Corp Monohydrate of venlafaxine hydrochloride and methods for its preparation (variants)

Also Published As

Publication number Publication date
CO5580818A2 (es) 2005-11-30
NO20042681L (no) 2004-06-25
EP1451145A1 (fr) 2004-09-01
US20060074131A1 (en) 2006-04-06
US20030109585A1 (en) 2003-06-12
US7030164B2 (en) 2006-04-18
NZ533363A (en) 2005-10-28
ZA200405248B (en) 2005-10-03
KR20050044673A (ko) 2005-05-12
CA2467593A1 (fr) 2003-06-19
MXPA04005305A (es) 2004-09-13
JP2005511736A (ja) 2005-04-28
BR0214742A (pt) 2004-09-14
AU2002348266A1 (en) 2003-06-23
PL370552A1 (en) 2005-05-30
CN1630631A (zh) 2005-06-22
ECSP045136A (es) 2004-07-23
RU2004120285A (ru) 2005-04-10
AR037744A1 (es) 2004-12-01
WO2003050075A1 (fr) 2003-06-19
HUP0402524A2 (hu) 2005-03-29
TW200301101A (en) 2003-07-01

Similar Documents

Publication Publication Date Title
IL162253A0 (en) Venlafaxine hydrochloride monohydrate and methods for the preparation thereof
IL196287A0 (en) Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride and processes for preparing thereof
EP1425279A4 (fr) Procede de preparation de tetrahydrobenzothiepines cristallines
HK1075044A1 (en) Crystalline polymorphic form of irinotecan hydrochloride
IL173736A0 (en) Process for the preparation of renzapride and intermediates thereof
HK1067123A1 (en) Novel crystalline polymorphic forms of lercanidipine hydrochloride and processes for their preparation
AU1234002A (en) Crystalline forms of venlafaxine hydrochloride
IL160721A0 (en) Crystalline forms of valacyclovir hydrochloride
IL162255A0 (en) Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
AU2002305162A1 (en) Polymorphs of fexofenadine hydrochloride
IL162171A0 (en) Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
AU2003298178A1 (en) Process for the preparation of an essentially pure polymorph of an n-pyrazolyl-n'-naphthyl-urea
IL159266A (en) Crystalline forms of fexofenadine and processes for the preparation thereof
IL141690A0 (en) Process for preparation of rasagiline and its salts
ZA200405245B (en) Venlafaxine hydrochloride monohydrate and methods for the preparation thereof
AU2002247945A1 (en) Manufacture of venlafaxine hydrochloride and crystalline polymorphs thereof
IL173887A0 (en) A process for the preparation of cilostazol and of the intermediates thereof
AU2001235970A1 (en) Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation
AU2003262928A8 (en) Crystalline form of nateglinide and process for preparation thereof
PL2181982T3 (pl) Sposób wytwarzania chlorowodorku wenlafaksyny w formie I
AU2002337634A1 (en) Process for the preparation of bupropion hydrochloride
AU2003274608A1 (en) Process for preparation of polymorphic form of sertraline hydrochloride
PL372137A1 (en) A novel polymorph of sertraline hydrochloride and composition containing thereof, novel methods for preparation of sertraline hydrochloride polymorphs and amorphous form
HU0104872D0 (en) New polymorphic forms of venlafaxine
AU2002347399A1 (en) Venlafaxine hydrochloride polymorphs