CO5580818A2 - Polimorfo cristalino novedoso del clorhidrato de venlafaxina y metodos pra la preparcion del mismo - Google Patents

Polimorfo cristalino novedoso del clorhidrato de venlafaxina y metodos pra la preparcion del mismo

Info

Publication number
CO5580818A2
CO5580818A2 CO04050947A CO04050947A CO5580818A2 CO 5580818 A2 CO5580818 A2 CO 5580818A2 CO 04050947 A CO04050947 A CO 04050947A CO 04050947 A CO04050947 A CO 04050947A CO 5580818 A2 CO5580818 A2 CO 5580818A2
Authority
CO
Colombia
Prior art keywords
venlafaxine
same
chlorhydrate
preparation
methods
Prior art date
Application number
CO04050947A
Other languages
English (en)
Inventor
Abdul Ali Nabi Kadum
Jun Han
Yong Jai Lee
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CO5580818A2 publication Critical patent/CO5580818A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1.- El clorhidrato de venlafaxina que tiene un patrón de difracción de rayos X que es sustancialmente el mismo que es mostrado en la Figura 1.5.- Un polimorfo cristalino del clorhidrato de venlafaxina que exhibe un patron de difracción de rayos X en polvo que tiene picos característicos expresados en grados 2? en alrededor de 5.67, 7.28, 9.14, 9.67, 10.77, 11.31, 14.01, 14.54, 14.85, 15.48, 15.81, 16.17, 16.94, 17.68, 18.02, 18.48, 19.29, 19.69, 20.46, 20.74, 21.86, 22.33, 22.67, 22.95, 23.17, 24.06, 24.61, 25.13, 26.62, 26.97, 27.64, 28.25, 29.01, 29.96, 31.01, 31.61, 32.75, 34.54, 35.50, 35.95 y 36.91.7.- Una composición farmacéutica que comprende una cantidad terapéuticamente efectiva del clorhidrato de venlafaxina de cualquiera de las reivindicaciones 1 a 6 y un portador o diluyente farmacéuticamente aceptable.
CO04050947A 2001-12-05 2004-06-01 Polimorfo cristalino novedoso del clorhidrato de venlafaxina y metodos pra la preparcion del mismo CO5580818A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33582201P 2001-12-05 2001-12-05

Publications (1)

Publication Number Publication Date
CO5580818A2 true CO5580818A2 (es) 2005-11-30

Family

ID=23313356

Family Applications (1)

Application Number Title Priority Date Filing Date
CO04050947A CO5580818A2 (es) 2001-12-05 2004-06-01 Polimorfo cristalino novedoso del clorhidrato de venlafaxina y metodos pra la preparcion del mismo

Country Status (21)

Country Link
US (2) US7030164B2 (es)
EP (1) EP1451145A1 (es)
JP (1) JP2005511736A (es)
KR (1) KR20050044673A (es)
CN (1) CN1630631A (es)
AR (1) AR037744A1 (es)
AU (1) AU2002348266A1 (es)
BR (1) BR0214742A (es)
CA (1) CA2467593A1 (es)
CO (1) CO5580818A2 (es)
EC (1) ECSP045136A (es)
HU (1) HUP0402524A2 (es)
IL (1) IL162255A0 (es)
MX (1) MXPA04005305A (es)
NO (1) NO20042681L (es)
NZ (1) NZ533363A (es)
PL (1) PL370552A1 (es)
RU (1) RU2004120285A (es)
TW (1) TW200301101A (es)
WO (1) WO2003050075A1 (es)
ZA (1) ZA200405248B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
US6906087B2 (en) * 2000-10-31 2005-06-14 Ciba Specialty Chemicals Corpation Crystalline forms of venlafaxine hydrochloride
KR20070045278A (ko) * 2004-07-22 2007-05-02 와이어쓰 신경계 질환 및 장애의 치료 방법
MX2007000853A (es) * 2004-07-22 2007-03-26 Wyeth Corp Procedimiento para el tratamiento de trastornos y dolencias del sistema nervioso.
US20060020014A1 (en) * 2004-07-22 2006-01-26 Wyeth Method for treating nervous system disorders and conditions
JP2009502798A (ja) * 2005-07-21 2009-01-29 ワイス 神経系障害および状態の処置方法
EP1824815A2 (en) * 2005-10-19 2007-08-29 Teva Pharmaceutical Industries Ltd. Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
NZ599480A (en) * 2007-02-21 2013-10-25 Sunovion Pharmaceuticals Inc Solid forms comprising (-)-o-desmethylvenlafaxine and uses thereof
CA2812227C (en) 2010-10-01 2015-11-24 Shan Dong Luye Pharmaceutical Co., Ltd. Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same
IN2015DN01662A (es) 2012-09-18 2015-07-03 Auspex Pharmaceuticals Inc
PL3265085T3 (pl) 2015-03-06 2022-11-07 Auspex Pharmaceuticals, Inc. Sposoby leczenia zaburzeń związanych z nieprawidłowymi ruchami mimowolnymi

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761501A (en) * 1983-10-26 1988-08-02 American Home Products Corporation Substituted phenylacetamides
US6440457B1 (en) 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
EP1153603B1 (en) * 1993-06-28 2006-10-18 Wyeth New treatments using phenethylamine derivatives
TW344661B (en) * 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
US5530013A (en) * 1994-02-14 1996-06-25 American Home Products Corporation Venlafaxine in the inducement of cognition enhancement
US5506270A (en) * 1995-01-30 1996-04-09 American Home Products Corporation Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women
US6274171B1 (en) * 1996-03-25 2001-08-14 American Home Products Corporation Extended release formulation of venlafaxine hydrochloride
UA77145C2 (en) * 1997-11-05 2006-11-15 Wyeth Corp Extended release dosage formulation
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
CZ20031298A3 (cs) * 2000-10-19 2003-10-15 Teva Pharmaceutical Industries Ltd. Způsob přípravy krystalické báze venlafaxinu a nových polymorfů hydrochloridu venlafaxinu
US6906087B2 (en) * 2000-10-31 2005-06-14 Ciba Specialty Chemicals Corpation Crystalline forms of venlafaxine hydrochloride
AU2001235970A1 (en) 2000-12-07 2002-06-18 Dr. Reddy's Research Foundation Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation
UA77234C2 (en) * 2001-12-05 2006-11-15 Wyeth Corp Monohydrate of venlafaxine hydrochloride and methods for its preparation (variants)

Also Published As

Publication number Publication date
RU2004120285A (ru) 2005-04-10
IL162255A0 (en) 2005-11-20
PL370552A1 (en) 2005-05-30
MXPA04005305A (es) 2004-09-13
JP2005511736A (ja) 2005-04-28
US20030109585A1 (en) 2003-06-12
ZA200405248B (en) 2005-10-03
TW200301101A (en) 2003-07-01
NO20042681L (no) 2004-06-25
CA2467593A1 (en) 2003-06-19
AR037744A1 (es) 2004-12-01
US7030164B2 (en) 2006-04-18
EP1451145A1 (en) 2004-09-01
US20060074131A1 (en) 2006-04-06
WO2003050075A1 (en) 2003-06-19
BR0214742A (pt) 2004-09-14
CN1630631A (zh) 2005-06-22
AU2002348266A1 (en) 2003-06-23
KR20050044673A (ko) 2005-05-12
HUP0402524A2 (hu) 2005-03-29
NZ533363A (en) 2005-10-28
ECSP045136A (es) 2004-07-23

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