IL160117A0 - Pulsatile release compositions and methods for enhanced gastrointestinal drug absorption - Google Patents
Pulsatile release compositions and methods for enhanced gastrointestinal drug absorptionInfo
- Publication number
- IL160117A0 IL160117A0 IL16011702A IL16011702A IL160117A0 IL 160117 A0 IL160117 A0 IL 160117A0 IL 16011702 A IL16011702 A IL 16011702A IL 16011702 A IL16011702 A IL 16011702A IL 160117 A0 IL160117 A0 IL 160117A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- release compositions
- drug absorption
- pulsatile release
- gastrointestinal drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/944,493 US20030124196A1 (en) | 2001-08-22 | 2001-08-22 | Pulsatile release compositions and methods for enhanced intestinal drug absorption |
PCT/US2002/026924 WO2003017940A2 (en) | 2001-08-22 | 2002-08-22 | Pulsatile release compositions and methods for enhanced gastrointestinal drug absorption |
Publications (1)
Publication Number | Publication Date |
---|---|
IL160117A0 true IL160117A0 (en) | 2004-06-20 |
Family
ID=25481510
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16011702A IL160117A0 (en) | 2001-08-22 | 2002-08-22 | Pulsatile release compositions and methods for enhanced gastrointestinal drug absorption |
IL160117A IL160117A (en) | 2001-08-22 | 2004-01-29 | Delayed release oral formulation for enhanced intestinal oligonucleotide absorption |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL160117A IL160117A (en) | 2001-08-22 | 2004-01-29 | Delayed release oral formulation for enhanced intestinal oligonucleotide absorption |
Country Status (7)
Country | Link |
---|---|
US (3) | US20030124196A1 (xx) |
EP (1) | EP1427289B1 (xx) |
JP (1) | JP4460290B2 (xx) |
AU (1) | AU2002332647B2 (xx) |
CA (1) | CA2458442C (xx) |
IL (2) | IL160117A0 (xx) |
WO (1) | WO2003017940A2 (xx) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
US20020141970A1 (en) * | 2001-03-05 | 2002-10-03 | Pettit Dean K. | Stable aqueous solutions of granulocyte macrophage colony-stimulating factor |
JP4370451B2 (ja) * | 2001-09-28 | 2009-11-25 | 大塚製薬株式会社 | 医薬組成物 |
US7763706B1 (en) * | 2003-07-17 | 2010-07-27 | Campina B.V. | Arginine/lysine-enriched peptides |
AU2004258949B2 (en) | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
AU2004258944B2 (en) | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
AU2004258953B2 (en) | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
JP4388322B2 (ja) * | 2003-07-31 | 2009-12-24 | 花王株式会社 | アポリポプロテインd分解抑制剤 |
AU2004264939A1 (en) | 2003-08-11 | 2005-02-24 | Middlebrook Pharmaceuticals, Inc. | Robust pellet |
CA2535398C (en) | 2003-08-12 | 2013-11-12 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
CA2535780A1 (en) | 2003-08-29 | 2005-03-17 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
AU2004273830B2 (en) | 2003-09-15 | 2011-03-24 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
KR20050104152A (ko) * | 2004-04-28 | 2005-11-02 | 최승호 | 경구용 약물의 흡수를 증진하는 약제학적 조성물 |
EP1744731A1 (en) * | 2004-04-28 | 2007-01-24 | Procarrier, Inc. | Oral formulation for delivery of poorly absorbed drugs |
EP1750862B1 (en) | 2004-06-04 | 2011-01-05 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing irbesartan |
EP1771158A4 (en) | 2004-07-02 | 2008-03-12 | Advancis Pharmaceutical Corp | TABLET FOR PULSED DELIVERY |
US8865197B2 (en) * | 2005-09-06 | 2014-10-21 | Israel Oceanographic And Limnological Research Ltd. | Food formulation for aquatic animals with integrated targeted delivery of bioactive agents |
JP2009511606A (ja) * | 2005-10-14 | 2009-03-19 | ハー・ルンドベック・アクチエゼルスカベット | エスシタロプラムおよびブプロピオンの低用量の併用を用いる中枢神経系障害の治療方法 |
AU2006304889A1 (en) * | 2005-10-14 | 2007-04-26 | H. Lundbeck A/S | Stable pharmaceutical formulations containing escitalopram and bupropion |
US8778924B2 (en) | 2006-12-04 | 2014-07-15 | Shionogi Inc. | Modified release amoxicillin products |
US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
US8299052B2 (en) | 2006-05-05 | 2012-10-30 | Shionogi Inc. | Pharmaceutical compositions and methods for improved bacterial eradication |
US20100226995A1 (en) * | 2007-11-12 | 2010-09-09 | Debrouse Daniel R | Microencapsulated bioactive agents for oral delivery and methods of use thereof |
RS56049B1 (sr) * | 2008-11-13 | 2017-09-29 | Nogra Pharma Ltd | Antisens kompozicije i postupci za pripremu i upotrebu istih |
AU2010306940A1 (en) | 2009-10-12 | 2012-06-07 | Smith, Larry | Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro |
WO2011048125A1 (en) | 2009-10-20 | 2011-04-28 | Santaris Pharma A/S | Oral delivery of therapeutically effective lna oligonucleotides |
AU2010339907A1 (en) | 2009-12-16 | 2012-07-05 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
US20110142889A1 (en) * | 2009-12-16 | 2011-06-16 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
US9101547B2 (en) * | 2011-08-04 | 2015-08-11 | Nano And Advanced Materials Institute Limited | Enteric-coated capsule containing cationic nanoparticles for oral insulin delivery |
EP2946773A1 (en) * | 2014-05-19 | 2015-11-25 | Tillotts Pharma AG | Modified release coated capsules |
US10570169B2 (en) | 2014-05-22 | 2020-02-25 | Ionis Pharmaceuticals, Inc. | Conjugated antisense compounds and their use |
FR3022462B1 (fr) * | 2014-06-18 | 2018-04-27 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Composition orale d'anticorps anti-tnfalpha |
US20180153984A1 (en) * | 2015-04-30 | 2018-06-07 | The Regents Of The University Of California | Adjuvant particles comprising adenosine receptor antagonists |
JP6950958B2 (ja) * | 2015-12-01 | 2021-10-13 | 国立大学法人 東京医科歯科大学 | 核酸を含む経腸投与用組成物 |
KR101741977B1 (ko) * | 2016-04-26 | 2017-05-31 | 한국교통대학교산학협력단 | 경구 투여용 유전자 전달을 위한 나노입자 및 이를 포함하는 약학 조성물 |
CA3043768A1 (en) | 2016-11-29 | 2018-06-07 | PureTech Health LLC | Exosomes for delivery of therapeutic agents |
FR3066115B1 (fr) | 2017-05-10 | 2019-06-28 | Universite de Bordeaux | Comprimes de vecteurs d'acides nucleiques |
EP3638213A4 (en) * | 2017-06-16 | 2021-03-24 | Altibio, Inc. | MODIFIED-RELEASE TIOPRONIN COMPOSITIONS, KITS AND METHODS FOR TREATING CYSTINURIA AND OTHER RELATED DISORDERS |
US10517889B2 (en) | 2017-09-08 | 2019-12-31 | Ionis Pharmaceuticals, Inc. | Modulators of SMAD7 expression |
CN109464703B (zh) * | 2018-11-29 | 2021-02-26 | 浙江瑞谷生物科技有限公司 | 一种骨修复材料及其制备方法和应用 |
CN114340615A (zh) * | 2019-08-12 | 2022-04-12 | 麻省理工学院 | 用于施用治疗剂的制品和方法 |
US20230263739A1 (en) * | 2020-06-26 | 2023-08-24 | Sensient Colors Llc | Enteric coating composition and method of making and using the same |
US20220184112A1 (en) * | 2020-11-10 | 2022-06-16 | Ionis Pharmaceuticals, Inc. | Compositions and methods for enhanced intestinal absorption of conjugated oligomeric compounds |
Family Cites Families (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3687808A (en) | 1969-08-14 | 1972-08-29 | Univ Leland Stanford Junior | Synthetic polynucleotides |
US4773907A (en) * | 1982-12-20 | 1988-09-27 | Alza Corporation | Primary delivery system comprising secondary dosage form |
ATE151286T1 (de) * | 1983-11-14 | 1997-04-15 | Columbia Lab Inc | Bioadhäsive mittel |
USRE33093E (en) * | 1986-06-16 | 1989-10-17 | Johnson & Johnson Consumer Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
US4713243A (en) | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
US5543508A (en) | 1987-12-15 | 1996-08-06 | Gene Shears Pty. Limited | Ribozymes |
GB8826116D0 (en) * | 1988-11-08 | 1988-12-14 | Danbiosyst Ltd | Adhesive drug delivery composition |
US4948580A (en) * | 1988-12-08 | 1990-08-14 | E. R. Squibb & Sons, Inc. | Muco-bioadhesive composition |
US5750136A (en) * | 1989-11-03 | 1998-05-12 | Riker Laboratories, Inc. | Bioadhesive composition and patch |
US5514788A (en) * | 1993-05-17 | 1996-05-07 | Isis Pharmaceuticals, Inc. | Oligonucleotide modulation of cell adhesion |
US5212295A (en) | 1990-01-11 | 1993-05-18 | Isis Pharmaceuticals | Monomers for preparation of oligonucleotides having chiral phosphorus linkages |
US5587361A (en) | 1991-10-15 | 1996-12-24 | Isis Pharmaceuticals, Inc. | Oligonucleotides having phosphorothioate linkages of high chiral purity |
US5284659A (en) | 1990-03-30 | 1994-02-08 | Cherukuri Subraman R | Encapsulated flavor with bioadhesive character in pressed mints and confections |
US5077051A (en) | 1990-04-10 | 1991-12-31 | Warner-Lambert Company | Sustained release of active agents from bioadhesive microcapsules |
CA2085342A1 (en) | 1990-06-14 | 1991-12-15 | Milton R. Kaplan | Stable aqueous drug suspensions |
US6096722A (en) * | 1990-08-14 | 2000-08-01 | Isis Pharmaceuticals Inc. | Antisense modulation of cell adhesion molecule expression and treatment of cell adhesion molecule-associated diseases |
US5595978A (en) * | 1990-08-16 | 1997-01-21 | Isis Pharmaceuticals, Inc. | Composition and method for treatment of CMV retinites |
US5370901A (en) * | 1991-02-15 | 1994-12-06 | Bracco International B.V. | Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients |
US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
IT1250421B (it) * | 1991-05-30 | 1995-04-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive. |
AU664561B2 (en) * | 1991-06-21 | 1995-11-23 | University Of Cincinnati, The | Orally administrable therapeutic proteins and method of making |
DE4125851A1 (de) | 1991-08-03 | 1993-02-04 | Storz E A Kg | Befestigungsvorrichtung fuer einen wagenheber |
US5192802A (en) * | 1991-09-25 | 1993-03-09 | Mcneil-Ppc, Inc. | Bioadhesive pharmaceutical carrier |
US5364634A (en) * | 1991-11-08 | 1994-11-15 | Southwest Research Institute | Controlled-release PH sensitive capsule and adhesive system and method |
US6197346B1 (en) * | 1992-04-24 | 2001-03-06 | Brown Universtiy Research Foundation | Bioadhesive microspheres and their use as drug delivery and imaging systems |
US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
US5330761A (en) * | 1993-01-29 | 1994-07-19 | Edward Mendell Co. Inc. | Bioadhesive tablet for non-systemic use products |
EP0804174A4 (en) * | 1993-07-21 | 1998-09-09 | Univ Kentucky Res Found | MULTI-CHAMBER HARD CAPSULES WITH CONTROLLED DELIVERY CHARACTERISTICS |
US5801154A (en) * | 1993-10-18 | 1998-09-01 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of multidrug resistance-associated protein |
US5876742A (en) * | 1994-01-24 | 1999-03-02 | The Regents Of The University Of California | Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method of preparation thereof |
US5539083A (en) | 1994-02-23 | 1996-07-23 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid combinatorial libraries and improved methods of synthesis |
US6228383B1 (en) * | 1994-03-03 | 2001-05-08 | Gs Development Ab | Use of fatty acid esters as bioadhesive substances |
EP0752855B1 (en) * | 1994-03-30 | 1999-06-09 | Gs Development Ab | Use of fatty acid esters as bioadhesive substances |
US5462728A (en) * | 1994-04-05 | 1995-10-31 | Blank; Izhak | Pharmaceutical compositions |
US5670163A (en) * | 1994-06-20 | 1997-09-23 | Kv Pharmaceuticals Company | Long acting GI and esophageal protectant |
EP0691124A1 (en) * | 1994-07-07 | 1996-01-10 | Sara Lee/DE N.V. | Mouth care products |
US5554380A (en) * | 1994-08-04 | 1996-09-10 | Kv Pharmaceutical Company | Bioadhesive pharmaceutical delivery system |
US6309853B1 (en) * | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
US5614222A (en) * | 1994-10-25 | 1997-03-25 | Kaplan; Milton R. | Stable aqueous drug suspensions and methods for preparation thereof |
US5545729A (en) | 1994-12-22 | 1996-08-13 | Hybridon, Inc. | Stabilized ribozyme analogs |
US5686106A (en) * | 1995-05-17 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form for colonic delivery |
US6248720B1 (en) * | 1996-07-03 | 2001-06-19 | Brown University Research Foundation | Method for gene therapy using nucleic acid loaded polymeric microparticles |
US5770627A (en) * | 1995-08-16 | 1998-06-23 | University Of Washington | Hydrophobically-modified bioadhesive polyelectrolytes and methods relating thereto |
US6130217A (en) * | 1995-09-20 | 2000-10-10 | Pfizer Inc | Compounds enhancing antitumor activity of other cytotoxic agents |
US5942253A (en) * | 1995-10-12 | 1999-08-24 | Immunex Corporation | Prolonged release of GM-CSF |
EP0871489A1 (en) | 1995-10-12 | 1998-10-21 | Gs Development Ab | A pharmaceutical composition for administration of an active substance to or through a skin or mucosal surface |
US5849322A (en) * | 1995-10-23 | 1998-12-15 | Theratech, Inc. | Compositions and methods for buccal delivery of pharmaceutical agents |
KR100459029B1 (ko) * | 1995-12-27 | 2006-03-27 | 얀센 파마슈티카 엔.브이. | 생점착성고체투여형 |
US6368586B1 (en) * | 1996-01-26 | 2002-04-09 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US5985312A (en) * | 1996-01-26 | 1999-11-16 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US5955096A (en) * | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
FR2762513B1 (fr) * | 1997-04-23 | 2003-08-22 | Permatec Pharma Ag | Comprimes bioadhesifs |
DE19718012C1 (de) * | 1997-04-29 | 1998-10-08 | Jenapharm Gmbh | Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe |
JP2000514095A (ja) * | 1997-04-30 | 2000-10-24 | アイシス・ファーマシューティカルス・インコーポレーテッド | 生物学的利用能を向上するためのオリゴヌクレオチド |
US5840329A (en) * | 1997-05-15 | 1998-11-24 | Bioadvances Llc | Pulsatile drug delivery system |
GB9710699D0 (en) * | 1997-05-24 | 1997-07-16 | Danbiosyst Uk | Gastro-retentive controlled release system |
DE69834038D1 (de) | 1997-07-01 | 2006-05-18 | Isis Pharmaceutical Inc | Zusammensetzungen und verfahren zur verabreichung von oligonukleotiden über die speiseröhre |
US5877309A (en) * | 1997-08-13 | 1999-03-02 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotides against JNK |
US5989535A (en) * | 1997-08-15 | 1999-11-23 | Soma Technologies | Polymeric bioadhesive emulsions and suspensions and methods of treatment |
US6187335B1 (en) * | 1997-12-31 | 2001-02-13 | Orasomal Technologies, Inc. | Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom |
US6200604B1 (en) * | 1998-03-27 | 2001-03-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US6350470B1 (en) * | 1998-04-29 | 2002-02-26 | Cima Labs Inc. | Effervescent drug delivery system for oral administration |
JP2003524586A (ja) | 1998-05-21 | 2003-08-19 | アイシス・ファーマシューティカルス・インコーポレーテッド | オリゴヌクレオチドの非−非経口投与のための組成物と方法 |
EP2127642A3 (en) * | 1998-08-13 | 2010-02-24 | Cima Labs, Inc. | Microemulsions as solid dosage forms for oral administration |
US6080580A (en) * | 1998-10-05 | 2000-06-27 | Isis Pharmaceuticals Inc. | Antisense oligonucleotide modulation of tumor necrosis factor-α (TNF-α) expression |
AU2367900A (en) | 1998-12-18 | 2000-07-03 | Bayer Corporation | Chewable drug delivery system |
US6355270B1 (en) * | 1999-01-11 | 2002-03-12 | The Regents Of The University Of California | Particles for oral delivery of peptides and proteins |
AU2547900A (en) | 1999-02-12 | 2000-08-29 | Ben-Gurion University Of The Negev Research & Development Authority | A biocompatible adhesive system and a bioadhesive drug delivery system with controllable release |
US6375963B1 (en) * | 1999-06-16 | 2002-04-23 | Michael A. Repka | Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof |
US6458383B2 (en) * | 1999-08-17 | 2002-10-01 | Lipocine, Inc. | Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin |
US6565873B1 (en) | 2000-10-25 | 2003-05-20 | Salvona Llc | Biodegradable bioadhesive controlled release system of nano-particles for oral care products |
ATE380022T1 (de) | 2001-01-31 | 2007-12-15 | Evonik Roehm Gmbh | Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen |
-
2001
- 2001-08-22 US US09/944,493 patent/US20030124196A1/en not_active Abandoned
-
2002
- 2002-08-22 WO PCT/US2002/026924 patent/WO2003017940A2/en active Application Filing
- 2002-08-22 CA CA2458442A patent/CA2458442C/en not_active Expired - Lifetime
- 2002-08-22 IL IL16011702A patent/IL160117A0/xx unknown
- 2002-08-22 EP EP02796423.8A patent/EP1427289B1/en not_active Expired - Lifetime
- 2002-08-22 JP JP2003522463A patent/JP4460290B2/ja not_active Expired - Lifetime
- 2002-08-22 AU AU2002332647A patent/AU2002332647B2/en not_active Expired
-
2004
- 2004-01-29 IL IL160117A patent/IL160117A/en active IP Right Grant
- 2004-12-01 US US11/000,814 patent/US7576067B2/en not_active Expired - Lifetime
-
2009
- 2009-06-16 US US12/485,675 patent/US20110256217A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP4460290B2 (ja) | 2010-05-12 |
EP1427289A2 (en) | 2004-06-16 |
EP1427289A4 (en) | 2006-06-28 |
WO2003017940A2 (en) | 2003-03-06 |
US7576067B2 (en) | 2009-08-18 |
JP2005505533A (ja) | 2005-02-24 |
WO2003017940A3 (en) | 2003-12-11 |
CA2458442A1 (en) | 2003-03-06 |
EP1427289B1 (en) | 2017-05-10 |
US20050196443A1 (en) | 2005-09-08 |
IL160117A (en) | 2013-03-24 |
CA2458442C (en) | 2012-05-22 |
AU2002332647B2 (en) | 2008-05-15 |
US20030124196A1 (en) | 2003-07-03 |
US20110256217A1 (en) | 2011-10-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL160117A0 (en) | Pulsatile release compositions and methods for enhanced gastrointestinal drug absorption | |
EP1407785A4 (en) | MEDICAL COMPOSITIONS | |
HK1065944A1 (en) | Medicinal compositions | |
IL159532A0 (en) | Enteral formulations | |
TWI319317B (en) | Modified release pharmaceutical formulation | |
EP1411904A4 (en) | PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE | |
SI1458377T1 (sl) | Tegaserodovi farmacevtski sestavki | |
HUP0303163A3 (en) | Tramadol-based pharmaceutical composition | |
GB0117057D0 (en) | Pharmaceutical composition | |
HK1065257A1 (en) | Medicinal composition | |
GB0108470D0 (en) | Pharmaceutical compositions and their use | |
EP1408896A4 (en) | PHARMACEUTICAL COMPOSITION | |
PL376840A1 (pl) | Kompozycja farmaceutyczna o przedłużonym uwalnianiu | |
GB0129117D0 (en) | Pharmaceutical composition | |
IL165069A0 (en) | Immediate release pharmaceutical formulation | |
GB0119848D0 (en) | Delayed and sustained drug release | |
GB0116107D0 (en) | Pharmaceutical composition | |
EP1421954A4 (en) | SLOW DRUG DELIVERY MATERIALS I IN VIVO / I | |
GB0127805D0 (en) | Pharmaceutical composition | |
HUP0401599A3 (en) | Extended release oral dosage form | |
PL370037A1 (en) | Pharmaceutical composition | |
IL153176A (en) | Phenylpiperazines and pharmaceutical compositions comprising them | |
AU2002360790A8 (en) | Compositions and methods for the therapeutic use of an atonal-associated sequence for a gastrointestinal condition | |
AU2002365136A8 (en) | Compositions and methods for controlled release | |
GB0114746D0 (en) | Medicinal composition |