IL160061A0 - Enzymatic resolution of t-butyl taxane derivatives - Google Patents
Enzymatic resolution of t-butyl taxane derivativesInfo
- Publication number
- IL160061A0 IL160061A0 IL16006102A IL16006102A IL160061A0 IL 160061 A0 IL160061 A0 IL 160061A0 IL 16006102 A IL16006102 A IL 16006102A IL 16006102 A IL16006102 A IL 16006102A IL 160061 A0 IL160061 A0 IL 160061A0
- Authority
- IL
- Israel
- Prior art keywords
- butyl
- enzymatic resolution
- taxane derivatives
- taxane
- derivatives
- Prior art date
Links
- 230000002255 enzymatic effect Effects 0.000 title 1
- -1 t-butyl taxane derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31375701P | 2001-08-21 | 2001-08-21 | |
| PCT/US2002/026810 WO2003016543A2 (fr) | 2001-08-21 | 2002-08-21 | Resolution enzymatique de derives t-butyl-taxane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL160061A0 true IL160061A0 (en) | 2004-06-20 |
Family
ID=23217015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16006102A IL160061A0 (en) | 2001-08-21 | 2002-08-21 | Enzymatic resolution of t-butyl taxane derivatives |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7063977B2 (fr) |
| EP (1) | EP1425407A4 (fr) |
| JP (1) | JP2007503201A (fr) |
| KR (1) | KR20040053114A (fr) |
| CN (1) | CN1294274C (fr) |
| AU (1) | AU2002323346B2 (fr) |
| BR (1) | BR0211999A (fr) |
| CZ (1) | CZ2004254A3 (fr) |
| HU (1) | HUP0500645A3 (fr) |
| IL (1) | IL160061A0 (fr) |
| MX (1) | MXPA04001631A (fr) |
| PL (1) | PL374278A1 (fr) |
| WO (1) | WO2003016543A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108084126A (zh) * | 2016-11-21 | 2018-05-29 | 山东国际生物科技园发展有限公司 | 化合物FuramycinsⅠ和Ⅱ及其制备方法和应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY110249A (en) | 1989-05-31 | 1998-03-31 | Univ Florida State | Method for preparation of taxol using beta lactam |
| US5175315A (en) | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| US5274124A (en) | 1991-09-23 | 1993-12-28 | Florida State University | Metal alkoxides |
| US5284865A (en) | 1991-09-23 | 1994-02-08 | Holton Robert A | Cyclohexyl substituted taxanes and pharmaceutical compositions containing them |
| US5243045A (en) | 1991-09-23 | 1993-09-07 | Florida State University | Certain alkoxy substituted taxanes and pharmaceutical compositions containing them |
| US5229526A (en) | 1991-09-23 | 1993-07-20 | Florida State University | Metal alkoxides |
| US5227400A (en) | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
| CA2087359A1 (fr) * | 1992-01-15 | 1993-07-16 | Ramesh N. Patel | Procedes enzymatiques pour la resolution d'un melange enantiometrique de composes utiles comme intermediaires pour la preparation de taxanes |
| US5939561A (en) * | 1992-03-10 | 1999-08-17 | Rhone-Poulence Rorer S.A. | Process for the preparation of β-phenylisoserine and β-lactam and their analogues |
| US5254580A (en) | 1993-01-19 | 1993-10-19 | Bristol-Myers Squibb Company | 7,8-cyclopropataxanes |
| US5294637A (en) | 1992-07-01 | 1994-03-15 | Bristol-Myers Squibb Company | Fluoro taxols |
| CA2100808A1 (fr) | 1992-10-01 | 1994-04-02 | Vittorio Farina | Desoxytaxols |
| US5420337A (en) * | 1992-11-12 | 1995-05-30 | E. R. Squibb & Sons, Inc. | Enzymatic reduction method for the preparation of compounds useful for preparing taxanes |
| US5973160A (en) | 1992-12-23 | 1999-10-26 | Poss; Michael A. | Methods for the preparation of novel sidechain-bearing taxanes |
| ATE309229T1 (de) | 1992-12-23 | 2005-11-15 | Bristol Myers Squibb Co | Seitenkette tragende taxanen und deren zwischenprodukten |
| US5840929A (en) | 1995-04-14 | 1998-11-24 | Bristol-Myers Squibb Company | C4 methoxy ether derivatives of paclitaxel |
| TW354293B (en) | 1995-06-06 | 1999-03-11 | Bristol Myers Squibb Co | Prodrugs of paclitaxel derivatives |
| DE69832173T2 (de) | 1997-05-27 | 2006-08-03 | IVAX RESEARCH, INC., Miami | Zusammensetzungen zur oralen verabreichung von taxanen und deren verwendung |
| US6916942B2 (en) | 2000-02-03 | 2005-07-12 | Bristol-Myers Squibb Company | Process for the preparation of C-4 carbonate taxanes |
| US6750246B1 (en) | 2000-02-03 | 2004-06-15 | Bristol-Myers Squibb Company | C-4 carbonate taxanes |
| US20050020685A1 (en) * | 2003-06-12 | 2005-01-27 | Skonezny Paul M. | Process for recovery of 6-aminopenicillanic acid from an aqueous discharge stream |
-
2002
- 2002-08-20 US US10/223,800 patent/US7063977B2/en not_active Expired - Fee Related
- 2002-08-21 CN CNB028162935A patent/CN1294274C/zh not_active Expired - Fee Related
- 2002-08-21 HU HU0500645A patent/HUP0500645A3/hu unknown
- 2002-08-21 WO PCT/US2002/026810 patent/WO2003016543A2/fr active Application Filing
- 2002-08-21 KR KR10-2004-7002472A patent/KR20040053114A/ko not_active Application Discontinuation
- 2002-08-21 EP EP02757323A patent/EP1425407A4/fr not_active Withdrawn
- 2002-08-21 IL IL16006102A patent/IL160061A0/xx unknown
- 2002-08-21 BR BR0211999-4A patent/BR0211999A/pt not_active IP Right Cessation
- 2002-08-21 MX MXPA04001631A patent/MXPA04001631A/es unknown
- 2002-08-21 PL PL02374278A patent/PL374278A1/xx unknown
- 2002-08-21 JP JP2003521850A patent/JP2007503201A/ja not_active Withdrawn
- 2002-08-21 CZ CZ2004254A patent/CZ2004254A3/cs unknown
- 2002-08-21 AU AU2002323346A patent/AU2002323346B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003016543A3 (fr) | 2003-07-24 |
| AU2002323346B2 (en) | 2007-09-20 |
| JP2007503201A (ja) | 2007-02-22 |
| HUP0500645A2 (hu) | 2005-09-28 |
| US7063977B2 (en) | 2006-06-20 |
| US20030069415A1 (en) | 2003-04-10 |
| PL374278A1 (en) | 2005-10-03 |
| KR20040053114A (ko) | 2004-06-23 |
| CN1545555A (zh) | 2004-11-10 |
| WO2003016543A2 (fr) | 2003-02-27 |
| MXPA04001631A (es) | 2004-07-08 |
| HUP0500645A3 (en) | 2009-03-02 |
| EP1425407A4 (fr) | 2007-02-21 |
| CZ2004254A3 (cs) | 2004-10-13 |
| EP1425407A2 (fr) | 2004-06-09 |
| CN1294274C (zh) | 2007-01-10 |
| BR0211999A (pt) | 2005-08-02 |
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