IL159535A0 - Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapy - Google Patents
Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapyInfo
- Publication number
- IL159535A0 IL159535A0 IL15953502A IL15953502A IL159535A0 IL 159535 A0 IL159535 A0 IL 159535A0 IL 15953502 A IL15953502 A IL 15953502A IL 15953502 A IL15953502 A IL 15953502A IL 159535 A0 IL159535 A0 IL 159535A0
- Authority
- IL
- Israel
- Prior art keywords
- tyr
- poly
- glu
- cells treated
- treated therewith
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 2
- 230000004112 neuroprotection Effects 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 abstract 3
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 2
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/47—Brain; Nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
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- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46432—Nervous system antigens
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Addiction (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/893,344 US6835711B2 (en) | 2001-06-28 | 2001-06-28 | Use of poly-Glu,Tyr for neuroprotective therapy |
PCT/IL2002/000517 WO2003002140A1 (en) | 2001-06-28 | 2002-06-27 | Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
IL159535A0 true IL159535A0 (en) | 2004-06-01 |
Family
ID=25401407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15953502A IL159535A0 (en) | 2001-06-28 | 2002-06-27 | Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapy |
Country Status (16)
Country | Link |
---|---|
US (1) | US6835711B2 (es) |
EP (1) | EP1406650B1 (es) |
JP (1) | JP4434729B2 (es) |
KR (1) | KR20040032825A (es) |
CN (1) | CN1326560C (es) |
AT (1) | ATE412419T1 (es) |
AU (1) | AU2002345323B2 (es) |
CA (1) | CA2451521C (es) |
DE (1) | DE60229639D1 (es) |
DK (1) | DK1406650T3 (es) |
ES (1) | ES2315371T3 (es) |
HK (1) | HK1064951A1 (es) |
IL (1) | IL159535A0 (es) |
MX (1) | MXPA03011926A (es) |
NZ (1) | NZ530261A (es) |
WO (1) | WO2003002140A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004060266A2 (en) * | 2003-01-07 | 2004-07-22 | Yeda Research And Development Co. Ltd. | Eye-drop vaccine containing copolymer poly-ye for therapeutic immunization |
US7399740B2 (en) * | 2001-06-28 | 2008-07-15 | Yeda Research And Development Co. Ltd. | Poly-Glu,Tyr for neuroprotective therapy |
HU228207B1 (hu) * | 2001-12-06 | 2013-01-28 | Yeda Res & Dev | Vakcina és eljárás mozgatóneuron-betegségek kezelésére |
JP4609855B2 (ja) * | 2003-06-16 | 2011-01-12 | 国立大学法人九州大学 | ヒト由来免疫担当細胞の製造方法 |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
WO2005056574A2 (en) * | 2003-12-09 | 2005-06-23 | Yeda Research And Development Co. Ltd. | Method and vaccine comprising copolymer 1 for treatment of psychiatric disorders |
WO2005055920A2 (en) * | 2003-12-09 | 2005-06-23 | Yeda Research And Development Co. Ltd. | Compositions and methods for treatment of psychiatric disorders |
WO2006057003A2 (en) * | 2004-11-29 | 2006-06-01 | Yeda Research And Development Co. Ltd. | Induction of neurogenesis and stem cell therapy in combination with copolymer 1 |
US9220813B2 (en) * | 2005-04-18 | 2015-12-29 | Holy Cross Hospital, Inc. | Cell therapy for limiting overzealous inflammatory reactions in tissue healing |
WO2009081395A1 (en) * | 2007-12-21 | 2009-07-02 | Ben Gurion University Of The Negev Research And Development Authority | A method of treating neurodegenerative diseases |
WO2009124170A1 (en) * | 2008-04-04 | 2009-10-08 | The Cleveland Clinic Foundation | Use of epineural sheath grafts for neural regeneration and protection |
BRPI0923177A2 (pt) * | 2008-12-19 | 2020-08-25 | Advanced Technologies And Regenerative Medicine, Llc | usos de composições para tratar dor neuropática e espacidade, as referidas composições, e kit |
CA2756600C (en) | 2009-03-26 | 2019-08-20 | Advanced Technologies And Regenerative Medicine, Llc | Human umbilical cord tissue cells as therapy for alzheimer's disease |
EP2473193A4 (en) * | 2009-09-04 | 2013-05-01 | Cleveland Clinic Foundation | METHOD OF NERVE TISSUE MANIPULATION |
US8377885B2 (en) | 2010-01-04 | 2013-02-19 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
EP3536333B1 (en) | 2010-01-04 | 2022-08-03 | Mapi Pharma Limited | Depot system comprising glatiramer acetate |
USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
ES2601892T3 (es) | 2011-04-21 | 2017-02-16 | Mapi Pharma Limited | Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes |
US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1039929A1 (en) | 1998-07-21 | 2000-10-04 | YEDA RESEARCH AND DEVELOPMENT Co. Ltd. | Activated t-cells and their uses |
-
2001
- 2001-06-28 US US09/893,344 patent/US6835711B2/en not_active Expired - Fee Related
-
2002
- 2002-06-27 ES ES02743592T patent/ES2315371T3/es not_active Expired - Lifetime
- 2002-06-27 NZ NZ530261A patent/NZ530261A/en not_active IP Right Cessation
- 2002-06-27 AU AU2002345323A patent/AU2002345323B2/en not_active Ceased
- 2002-06-27 KR KR10-2003-7016949A patent/KR20040032825A/ko not_active Application Discontinuation
- 2002-06-27 EP EP02743592A patent/EP1406650B1/en not_active Expired - Lifetime
- 2002-06-27 CA CA2451521A patent/CA2451521C/en not_active Expired - Fee Related
- 2002-06-27 DK DK02743592T patent/DK1406650T3/da active
- 2002-06-27 MX MXPA03011926A patent/MXPA03011926A/es active IP Right Grant
- 2002-06-27 JP JP2003508379A patent/JP4434729B2/ja not_active Expired - Fee Related
- 2002-06-27 IL IL15953502A patent/IL159535A0/xx unknown
- 2002-06-27 WO PCT/IL2002/000517 patent/WO2003002140A1/en active Application Filing
- 2002-06-27 DE DE60229639T patent/DE60229639D1/de not_active Expired - Lifetime
- 2002-06-27 CN CNB028165462A patent/CN1326560C/zh not_active Expired - Fee Related
- 2002-06-27 AT AT02743592T patent/ATE412419T1/de not_active IP Right Cessation
-
2004
- 2004-10-12 HK HK04107851.9A patent/HK1064951A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2451521C (en) | 2011-05-17 |
DE60229639D1 (de) | 2008-12-11 |
CN1547482A (zh) | 2004-11-17 |
KR20040032825A (ko) | 2004-04-17 |
MXPA03011926A (es) | 2004-03-26 |
JP2005502616A (ja) | 2005-01-27 |
AU2002345323B2 (en) | 2006-12-21 |
ATE412419T1 (de) | 2008-11-15 |
DK1406650T3 (da) | 2009-03-02 |
WO2003002140A1 (en) | 2003-01-09 |
EP1406650B1 (en) | 2008-10-29 |
CN1326560C (zh) | 2007-07-18 |
NZ530261A (en) | 2006-06-30 |
EP1406650A1 (en) | 2004-04-14 |
CA2451521A1 (en) | 2003-01-09 |
JP4434729B2 (ja) | 2010-03-17 |
HK1064951A1 (en) | 2005-02-08 |
US6835711B2 (en) | 2004-12-28 |
ES2315371T3 (es) | 2009-04-01 |
US20030003082A1 (en) | 2003-01-02 |
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